{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T05:39:58Z","timestamp":1777354798787,"version":"3.51.4"},"reference-count":27,"publisher":"American Geophysical Union (AGU)","issue":"4","license":[{"start":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:00:00Z","timestamp":1775692800000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["agupubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["GeoHealth"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The Atoyac river basin is one of the most polluted watershed basins in Mexico. Recent studies have reported the presence of organochlorine pesticides (OCPs) in this highly urbanized region through environmental monitoring, raising concerns about potential health risks, particularly for children and adolescents. We still lack information about its human exposure through biological samples that represent a more realistic measure of OCPs body burden. To evaluate, we compared the serum concentrations of OCPs in children and adolescents living within and outside the Atoyac watershed basin. We included 428 individuals under 20\u00a0years old who participated as controls in a population\u2010based study conducted in three central\u2010southern Mexican states (2021\u20132024). We collected sociodemographic characteristics through face\u2010to\u2010face interviews and obtained serum samples in which we quantified 24 OCPs by gas chromatography. To georeference, we classified the participants as living within or outside the Atoyac basin and compared their respective serum concentrations for those OCPs detected over 10% of samples. We found two heterogeneous spatial distribution patterns of OCPs serum concentrations. HCB, dieldrin, oxychlordane, and endosulfan sulfate were higher in the Atoyac basin, with the two formers being statistically significant. In contrast,\n                    <jats:italic>p<\/jats:italic>\n                    ,\n                    <jats:italic>p<\/jats:italic>\n                    \u2032\u2010DDE was significantly higher outside the Atoyac basin. The two patterns of exposure between the two regions emphasized one pattern driven by industry and agriculture, and the second driven by vector\u2010borne disease control. It reinforces the need for regulation and increased monitoring in the Atoyac river basin to provide information about adverse health effects in children and adolescents.\n                  <\/jats:p>","DOI":"10.1029\/2025gh001711","type":"journal-article","created":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T17:10:58Z","timestamp":1775754658000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Spatial Distribution of Organochlorine Pesticide Serum Concentrations in Mexican Children and Adolescents Living in and Out the Polluted Atoyac Watershed Basin"],"prefix":"10.1029","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5360-5861","authenticated-orcid":false,"given":"Sailing Jane Tak","family":"Tang","sequence":"first","affiliation":[{"name":"Division of International Health Department of Environmental Medicine and Public Health Icahn School of Medicine at Mount Sinai  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5164-9534","authenticated-orcid":false,"given":"Rodrigo","family":"Ugalde\u2010Resano","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Salud Poblacional Instituto Nacional de Salud P\u00fablica  Cuernavaca M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5195-5163","authenticated-orcid":false,"given":"\u00c1ngel","family":"M\u00e9rida\u2010Ortega","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Salud Poblacional Instituto Nacional de Salud P\u00fablica  Cuernavaca M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Rodriguez\u2010Montoyo","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Epidemiology School of Public Health University of Puerto Rico Medical Sciences Campus  San Juan PR USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adamarie","family":"M\u00e1rquez\u2010Acevedo","sequence":"additional","affiliation":[{"name":"Department of Animal Veterinary and Food Science College of Agricultural Life Sciences University of Idaho  Moscow ID USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5411-3949","authenticated-orcid":false,"given":"Mariano E.","family":"Cebri\u00e1n","sequence":"additional","affiliation":[{"name":"Departamento de Toxicolog\u00eda Centro de Investigaci\u00f3n y de Estudios Avanzados del Instituto Polit\u00e9cnico Nacional  Ciudad de M\u00e9xico M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8070-9727","authenticated-orcid":false,"given":"Juan C.","family":"N\u00fa\u00f1ez\u2010Enr\u00edquez","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n de Investigaci\u00f3n en Salud Unidad M\u00e9dica de Alta Especialidad Hospital de Pediatr\u00eda Centro M\u00e9dico Nacional Siglo XXI Instituto Mexicano del Seguro Social (IMSS)  Ciudad de M\u00e9xico M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0727-2837","authenticated-orcid":false,"given":"Janet","family":"Flores\u2010Lujano","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n M\u00e9dica en Epidemiolog\u00eda Cl\u00ednica Hospital de Pediatr\u00eda Centro M\u00e9dico Nacional Siglo XXI Instituto Mexicano del Seguro Social (IMSS)  Ciudad de M\u00e9xico M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3245-8337","authenticated-orcid":false,"given":"Lizbeth","family":"L\u00f3pez\u2010Carillo","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Salud Poblacional Instituto Nacional de Salud P\u00fablica  Cuernavaca M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"13","published-online":{"date-parts":[[2026,4,9]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Toxicological profile for endosulfan","author":"Agency for Toxic Substances and Disease Registry (ATSDR)","year":"2015"},{"key":"e_1_2_10_3_1","volume-title":"Toxicological profile for hexachlorobenzene","author":"Agency for Toxic Substances and Disease Registry (ATSDR)","year":"2015"},{"key":"e_1_2_10_4_1","volume-title":"Toxicological profile for Aldrin and Dieldrin","author":"Agency for Toxic Substances and Disease Registry (ATSDR)","year":"2022"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheh.2019.113426"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.8528"},{"key":"e_1_2_10_7_1","unstructured":"Bejarano Gonz\u00e1lez F. 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