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As the world's most populous country located in temperate and subtropical zones, China is highly vulnerable to temperature\u2010related mortality, with distinct yearly and population disparities in health risks. To investigate the impact of non\u2010optimal temperature exposure on China's all\u2010causes mortality during 1990\u20132023 and project future trends (2024\u20132050) under different climate change scenarios. Integrated CN05.1 gridded observational data, CMIP6 climate data (SSP2\u20104.5 and SSP5\u20108.5 scenarios), SimmEX extreme temperature indices data, and GBD 2023 disease burden data. We applied Spearman's correlation analysis, Joinpoint regression, Age\u2010Period\u2010Cohort analysis, and restricted cubic spline models for trend quantification and future projections. Non\u2010optimal temperature\u2010related deaths increased, while age\u2010standardized mortality rate declined significantly. Low\u2010temperature exposure remained the primary risk, but high\u2010temperature\u2010related health impacts intensified notably. The elderly (\u226580\u00a0years) and individuals with cardio\u2010cerebrovascular or respiratory diseases were the most susceptible. Climate warming showed significant correlations with most cause\u2010specific mortalities. Future projections revealed divergent disease risk trends under the two emission scenarios, with some diseases facing elevated risks. Non\u2010optimal temperature exposure exerts heterogeneous impacts on China's all\u2010causes mortality, with high\u2010temperature risks becoming increasingly prominent amid global warming. Targeted prevention and control strategies tailored to age, disease types, and emission scenarios are crucial to mitigate temperature\u2010related health burdens.<\/jats:p>","DOI":"10.1029\/2026gh001897","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T11:52:07Z","timestamp":1789127527000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Climate Warming on All\u2010Causes Mortality in China: The Role of Non\u2010Optimal Temperature Exposure and Multi\u2010Scenario Projections to 2050"],"prefix":"10.1029","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2713-6106","authenticated-orcid":false,"given":"Yujun","family":"He","sequence":"first","affiliation":[{"name":"Department of Traditional Chinese Medicine Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University  Taizhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conglin","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Traditional Chinese Medicine Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University  Taizhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dejun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Spinal Manipulation in Traditional Chinese Medicine Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University  Taizhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"He","sequence":"additional","affiliation":[{"name":"Department of Atmospheric Science China University of Geosciences  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Traditional Chinese Medicine Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University  Taizhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuequan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University  Taizhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoyang","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Acupuncture and Tuina Hunan University of Chinese Medicine  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao\u2010Hsin","family":"Tung","sequence":"additional","affiliation":[{"name":"Evidence\u2010Based Medicine Center Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University  Taizhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"13","published-online":{"date-parts":[[2026,9,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2542\u20105196(25)00054\u20103"},{"key":"e_1_2_9_3_1","article-title":"[Effects of climate change on public health 2015\u20132020. 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