{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T21:35:47Z","timestamp":1775511347235,"version":"3.50.1"},"reference-count":39,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2002,1,15]],"date-time":"2002-01-15T00:00:00Z","timestamp":1011052800000},"content-version":"vor","delay-in-days":259,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Allergy"],"published-print":{"date-parts":[[2001,5]]},"abstract":"<jats:p> <jats:bold>Background:<\/jats:bold> Epidemiologic data on asthma and allergies among adults are mainly based on questionnaires: this study validates the questions on asthma, allergic rhinitis, and conjunctivitis of a new Finnish questionnaire.<\/jats:p><jats:p> <jats:bold>Methods:<\/jats:bold> To validate questions used in a country\u2010wide study among university students aged 18\u201325 years, we examined 150 subjects who had ever reported asthma or wheezing, and 140 without asthma symptoms. Questions were validated in relation to current diseases including<\/jats:p><jats:p>1)\u2003symptoms detected during the preceding year at the physician's interview<\/jats:p><jats:p>2)\u2003objective measurements, such as methacholine challenge, skin prick tests, and specific IgE.<\/jats:p><jats:p>Data were adjusted for original proportions of \u201casthmatics\u201d and \u201cnonasthmatics\u201d in the questionnaire study.<\/jats:p><jats:p> <jats:bold>Results:<\/jats:bold> Questions on \u201creported asthma\u201d and \u201cdoctor\u2010diagnosed asthma\u201d had good positive predictive value (PPV) and specificity in diagnosing current asthma. The question on \u201cattacks of shortness of breath with wheezing\u201d, and especially the question on \u201ccough with wheezing\u201d were most sensitive. Questions on \u201callergic nasal symptoms\u201d and \u201callergic eye symptoms\u201d that were \u201crelated to pollen or animals\u201d were sensitive, but a further question on doctor's diagnosis yielded higher specificity and PPV.<\/jats:p><jats:p> <jats:bold>Conclusions:<\/jats:bold> Diagnosis\u2010based questions were found suitable for risk\u2010factor studies, because of their good specificity and PPV, and symptom\u2010based questions for screening, because they were highest in sensitivity.<\/jats:p>","DOI":"10.1034\/j.1398-9995.2001.056005377.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T01:46:27Z","timestamp":1047347187000},"page":"377-384","source":"Crossref","is-referenced-by-count":113,"title":["Validation of a new questionnaire on asthma, allergic rhinitis, and conjunctivitis in young 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