{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T01:22:12Z","timestamp":1774315332963,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,10,9]],"date-time":"2008-10-09T00:00:00Z","timestamp":1223510400000},"content-version":"vor","delay-in-days":3204,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Allergy"],"published-print":{"date-parts":[[2000,1]]},"abstract":"<jats:p> <jats:bold>Background:<\/jats:bold> The sensitizing potency of formaldehyde and phenol during anatomy dissecting was investigated. The objective was to determine whether exposure induces specific IgE or IgG against formaldehyde\u2010albumin or phenol\u2010albumin.<\/jats:p><jats:p> <jats:bold>Methods:<\/jats:bold> In 27 medical students, specific IgE against formaldehyde\u2010albumin by RAST plus ELISA and specific lgE against phenol\u2010albumin by ELISA were assessed. In addition, specific IgG against formaldehyde\u2010albumin was assessed in 23 students. Symptoms before and during dissecting were assessed, and indoor formaldehyde and phenol were measured.<\/jats:p><jats:p> <jats:bold>Results:<\/jats:bold> Mean indoor formaldehyde was 0.265\u00b10.07 mg\/m<jats:sup>3<\/jats:sup>, and mean indoor phenol was 4.65\u00b12.96 mg\/m3. Specific IgE\/IgG against formaldehyde\u2010albumin was not found at the beginning. Four students developed specific IgE against formaldehyde\u2010albumin (RAST classes of \u22652.0), and all four also had specific IgE in the ELISA, but IgG against formaldehyde\u2010albumin was not found. Specific IgE against phenol\u2010albumin was not seen. Itch and paresthesia of the hands (<jats:italic>P<\/jats:italic>P&lt;0.00001), dizziness (<jats:italic>P<\/jats:italic>&lt;0.008), burning eyes (<jats:italic>P<\/jats:italic>&lt;0.01), headache, sneezing, epistaxis, gingival bleeding, oral or pharyngeal itch, and shortness of breath were experienced.<\/jats:p><jats:p> <jats:bold>Conclusion:<\/jats:bold> Formaldehyde exposure during dissecting may induce specific IgE, but not IgG, against formaldehyde\u2010albumin. Sensitization did not correlate with symptoms.<\/jats:p>","DOI":"10.1034\/j.1398-9995.2000.00307.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T01:41:59Z","timestamp":1047346919000},"page":"84-87","source":"Crossref","is-referenced-by-count":56,"title":["Exposure to formaldehyde and phenol during an anatomy dissecting course: sensitizing potency of formaldehyde in medical students"],"prefix":"10.1111","volume":"55","author":[{"given":"F.","family":"Wantke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Focke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Hemmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Bracun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Wolf\u2010Abdolvahab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"G\u00f6tz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Jarisch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"G\u00f6tz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Tschabitscher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Gann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Tappler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,10,9]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700260106"},{"key":"e_1_2_6_3_2","first-page":"837","article-title":"Formaldehyde and phenol exposure during an anatomy dissecting course: a possible source for IgE\u2010mediated sensitization?","volume":"51","author":"Wantke F","year":"1996","journal-title":"Allergy"},{"key":"e_1_2_6_4_2","first-page":"55","article-title":"Enzyme immunoassays in diagnostic medicine. 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