{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T08:10:03Z","timestamp":1774339803407,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,10,9]],"date-time":"2008-10-09T00:00:00Z","timestamp":1223510400000},"content-version":"vor","delay-in-days":3113,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Allergy"],"published-print":{"date-parts":[[2000,4]]},"abstract":"<jats:p> <jats:bold>Background<\/jats:bold>: Sensitization to pollen and spores of the Southeast Asian tropical region is not well documented. This study evaluated the allergenicity of the tropical airspora in Singapore.<\/jats:p><jats:p> <jats:bold>Methods<\/jats:bold>: On the basis of the results of an aerobiologic survey of the airspora profile of Singapore, crude extracts of 23 main spore (fungal and fern) and pollen types were prepared. A total of 231 patients with asthma and\/or allergic rhinitis and 76 healthy controls were evaluated by skin prick test (SPT). Total and specific IgE levels were also quantified by the fluorescence allergosorbent test (FAST).<\/jats:p><jats:p> <jats:bold>Results<\/jats:bold>: All 23 allergenic extracts tested elicited positive SPT responses. Among the patients with atopic diseases, extracts of oil\u2010palm pollen (<jats:italic>Elaeis guineensis<\/jats:italic>) were observed to have the highest frequency of positive reactions (40%), followed by extracts of resam\u2010fern spores (<jats:italic>Dicranopteris linearis<\/jats:italic>) (34%) and sea\u2010teak pollen (<jats:italic>Podocarpus polystachyus<\/jats:italic>) (33.8%). Fungal spores with the highest SPT responses were <jats:italic>Curvularia<\/jats:italic> spp. (26\u201332%) and <jats:italic>Drechslera<\/jats:italic>\u2010like spores (31%). Positive responses to these extracts correlated with total serum IgE levels of the subjects and were significantly associated with the presence of atopic disease.<\/jats:p><jats:p> <jats:bold>Conclusions<\/jats:bold>: We have documented sensitization to tropical pollen and spores in our population. Its association with atopy suggests that it has a role in allergic diseases in the tropics.<\/jats:p>","DOI":"10.1034\/j.1398-9995.2000.00308.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T01:43:18Z","timestamp":1047346998000},"page":"340-347","source":"Crossref","is-referenced-by-count":65,"title":["Evaluation of the allergenicity of tropical pollen and airborne spores in Singapore"],"prefix":"10.1111","volume":"55","author":[{"given":"F. T.","family":"Chew","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. H.","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. S.","family":"Shang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. D.","family":"Siti Dahlia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. Y. T.","family":"Goh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. W.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. T. W.","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. 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