{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T15:53:50Z","timestamp":1765727630010},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2002,7,1]],"date-time":"2002-07-01T00:00:00Z","timestamp":1025481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2002,8]]},"abstract":"<jats:p>Background:\u2002The epidemiology of nocardiosis in the tropics among renal transplant recipients has not been reported.<\/jats:p><jats:p>Methods:\u2002An evaluation of nocardiosis for 30\u2003yr in one of the large transplant centres in South Asian region.<\/jats:p><jats:p>Results:\u2002Of the 1968 patients who received primary renal allografts at Christian Medical College &amp; Hospital, 27 patients developed nocardiosis over 30\u2003yr. Early nocardiosis (\u2264\u20032\u2003yr) was associated with chronic liver disease and the use of cyclosporin (CsA) as compared with its later occurrence (&gt;2\u2003yr). Seventeen patients (63%) had two or more associated post\u2010transplant infections, of whom 10 had tuberculosis. Mortality in these patients was associated with chronic liver disease.<\/jats:p><jats:p>Conclusions:\u2002Nocardiosis manifests earlier (&lt;2\u2003yr) in CsA treated patients who have chronic liver disease. Among renal transplant recipients of the tropics nocardiosis is a marker of a high susceptibility to tuberculosis and other infections, the association with tuberculosis is stronger in those developing early nocardiosis (&lt;2\u2003yr). Chronic liver disease is a risk factor for death in patients with nocardiosis especially when associated with tuberculosis. This report constitutes the largest single centre experience among renal transplant recipients.<\/jats:p>","DOI":"10.1034\/j.1399-0012.2002.01145.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T13:50:01Z","timestamp":1047390601000},"page":"285-289","source":"Crossref","is-referenced-by-count":15,"title":["Nocardiosis in tropical renal transplant recipients"],"prefix":"10.1111","volume":"16","author":[{"given":"George T","family":"John","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viswanathan","family":"Shankar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abi M","family":"Abraham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary S","family":"Mathews","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulose P","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chakko K","family":"Jacob","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,7]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000182855"},{"key":"e_1_2_6_3_2","doi-asserted-by":"crossref","first-page":"S 264","DOI":"10.1681\/ASN.V212s264","article-title":"Opportunistic fungal and bacterial infection in the renal transplant recipient","volume":"2","author":"TOLKOFF\u2010RUBIN NE","year":"1992","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_6_4_2","first-page":"429","article-title":"A trial of low dose steroid in renal transplantation","volume":"35","author":"HARIHARAN S","year":"1987","journal-title":"J Assoc Phys India"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(87)90169-6"},{"key":"e_1_2_6_6_2","first-page":"779","article-title":"Pulmonary Infections after kidney transplantation","volume":"47","author":"JHA R","year":"1999","journal-title":"J Assoc Physicians India"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198901000-00003"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199603270-00022"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.7.2.213"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.0600031148.x"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/clind\/16.4.505"},{"key":"e_1_2_6_12_2","first-page":"53","article-title":"Prevalence of Nocardia species in the soil of Patiala area","volume":"36","author":"GOEL S","year":"1993","journal-title":"Indian J Pathol Microbiol"},{"key":"e_1_2_6_13_2","first-page":"123","article-title":"An outbreak of Nocardia asteroides infection in a renal transplant unit","volume":"198","author":"LOVETT IS","year":"1981","journal-title":"Q J Med"},{"key":"e_1_2_6_14_2","first-page":"883","article-title":"Clinical and laboratory profile of AIDS in India","volume":"5","author":"KAUR A","year":"1992","journal-title":"J Acquir Immune Defic Syndr"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198901000-00003"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/4.2.315"},{"key":"e_1_2_6_17_2","first-page":"74","article-title":"Nocardiosis in transplant recipients","volume":"5","author":"CHAPMAN SW","year":"1990","journal-title":"Seminars Resp Infect"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199457110-00029"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1399-0012.2002.01145.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1399-0012.2002.01145.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1034\/j.1399-0012.2002.01145.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T22:12:00Z","timestamp":1697580720000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1034\/j.1399-0012.2002.01145.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,7]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2002,8]]}},"alternative-id":["10.1034\/j.1399-0012.2002.01145.x"],"URL":"https:\/\/doi.org\/10.1034\/j.1399-0012.2002.01145.x","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,7]]}}}