{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T11:21:48Z","timestamp":1772018508501,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2003,2,12]],"date-time":"2003-02-12T00:00:00Z","timestamp":1045008000000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2003,2]]},"abstract":"<jats:p><jats:bold>Abstract:<\/jats:bold> The aim of this report is to describe a rare complication of clostridium difficile (CD) disease, the occurrence of an inflammatory pseudotumor that caused intestinal obstruction in a liver transplant recipient. A 9\u2010month\u2010old girl underwent liver transplantation for biliary atresia. She was given tacrolimus as primary immunosuppressive therapy. Three months after liver transplantation, she presented with febrile protracted bloody diarrhea and failure to thrive. A diagnosis of post\u2010transplant lymphoproliferative disease associated with Epstein\u2013Barr virus infection was initially made on histological examination of duodenal biopsies. Tacrolimus was discontinued. Despite treatment with anti\u2010CD20 monoclonal antibodies the child's condition deteriorated and she presented with intestinal occlusion. A mass at the ascending colon was seen on the computed tomography scan mimicking lymphoma and the child underwent surgical laparotomy. Histological examination of the mass showed typical pathological lesions of inflammatory pseudotumor and CD pseudomembranous colitis. Diagnosis of CD disease was confirmed upon the identification of CD toxin A in stools. She was successfully treated by metronidazole and \u03b3\u2010globulin perfusions. Delayed diagnosis and anti\u2010CD20 monoclonal antibodies therapy (associated with hypogammaglobulinemia) possibly played a major role in the severity of CD pseudomembranous colitis and in the occurrence of an inflammatory pseudotumor.<\/jats:p>","DOI":"10.1034\/j.1399-3046.2003.02044.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T18:59:26Z","timestamp":1047495566000},"page":"76-79","source":"Crossref","is-referenced-by-count":24,"title":["Clostridium difficile colitis associated with inflammatory pseudotumor in a liver transplant recipient"],"prefix":"10.1034","volume":"7","author":[{"given":"Panayotis","family":"Lykavieris","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monique","family":"Fabre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Pariente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yves\u2010Marie","family":"Lezeau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominique","family":"Debray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,2,12]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19900401)65:7<1583::AID-CNCR2820650722>3.0.CO;2-L"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.73.856.98"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2001.20045"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026665609461"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19960215)77:4<778::AID-CNCR25>3.0.CO;2-X"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19930515)71:10<2934::AID-CNCR2820711008>3.0.CO;2-Z"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1005441106719"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2000-3811"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-200009000-00021"},{"key":"e_1_2_5_11_2","first-page":"155","article-title":"Detection of Epstein\u2013Barr virus in inflammatory pseudotumor","volume":"15","author":"Arber DA","year":"1998","journal-title":"Semin Diagn Pathol"},{"key":"e_1_2_5_12_2","first-page":"328","article-title":"Pancreatic inflammatory pseudotumor with persistent hyperinsulinemia and hypoglycemia following long term pancreatic transplantation","volume":"71","author":"Remberger K","year":"1987","journal-title":"Verh Dtsch Ges Pathol"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-200009000-00004"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-0012.1999.130407.x"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(98)01287-1"},{"key":"e_1_2_5_16_2","first-page":"606","article-title":"Atypical clostridium difficile colitis in a heart transplant recipient (letter)","volume":"14","author":"Nadir A","year":"1995","journal-title":"J Heart Lung Transplant"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026682131847"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199302000-00038"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1399-3046.2003.02044.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1034\/j.1399-3046.2003.02044.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T19:49:31Z","timestamp":1697226571000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1034\/j.1399-3046.2003.02044.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,2]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2003,2]]}},"alternative-id":["10.1034\/j.1399-3046.2003.02044.x"],"URL":"https:\/\/doi.org\/10.1034\/j.1399-3046.2003.02044.x","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,2]]}}}