{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T17:43:54Z","timestamp":1773078234194,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2002,4,19]],"date-time":"2002-04-19T00:00:00Z","timestamp":1019174400000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2002,4]]},"abstract":"<jats:p><jats:bold>Background:\u2003<\/jats:bold> The study tested the hypothesis that the incidence of hypotension during spinal anaesthesia for caesarean section is less in parturients who remain in the sitting position for 3\u2003min compared with parturients who are placed in the modified supine position immediately after induction of spinal anesthesia.<\/jats:p><jats:p><jats:bold>Methods:\u2003<\/jats:bold> Spinal anaesthesia was induced with the woman in the sitting position using 2.8\u2003ml hyperbaric bupivacaine 0.5% at the L<jats:sub>3\u22124<\/jats:sub> or L<jats:sub>2\u22123<\/jats:sub> interspace. Ninety\u2010eight patients scheduled for elective caesarean section under spinal anaesthesia were randomised to assume the supine position on an operating table tilted 10\u00b0 to the left (modified supine position) immediately after spinal injection (group 0, n=52) or to remain in the sitting position for 3\u2003min before they also assumed the modified supine position (group 3, n=46). Isotonic saline 2\u2013300\u2003ml was given intravenously over 15\u2003min before spinal injection followed by 15\u2003ml\/kg over 15\u201320\u2003min after induction of spinal anaesthesia. If the systolic blood pressure decreased to less than 70% of baseline or to less than 100\u2003mmHg or if there was any complaint of nausea, ephedrine was given in 5\u2003mg boluses intravenously every 2\u2003min.<\/jats:p><jats:p><jats:bold>Results:\u2003<\/jats:bold> The blood pressure decreased significantly in both groups following spinal injection (<jats:italic>P&lt;<\/jats:italic>0.001). Blood pressure variations over time differed significantly between the two groups (<jats:italic>P&lt;<\/jats:italic>0.05). However, the incidence of maternal hypotension before delivery was similar in the two groups. The difference was caused by the time to the blood pressure nadir being significantly shorter in group 0 compared with group 3 (9.1\u00b14.5\u2003min vs. 11.7\u00b13.7\u2003min, <jats:italic>P<\/jats:italic>&lt;0.01). Similar numbers of patients received rescue with ephedrine before delivery: 35 (67%) in group 0 vs. 26 (57%) in group 3 (NS). The mean total dose of ephedrine before delivery was 10.9\u2003mg in group 0 vs. 9.2\u2003mg in group 3 (NS). There were no differences in neonatal outcome between the two groups.<\/jats:p><jats:p><jats:bold>Conclusion:\u2003<\/jats:bold> At elective caesarean section, a 3\u2010min delay before supine positioning does not influence the incidence of maternal hypotension after induction of spinal anaesthesia in the sitting position with 2.8\u2003ml of bupivacaine 0.5% with 8% dextrose.<\/jats:p>","DOI":"10.1034\/j.1399-6576.2002.460419.x","type":"journal-article","created":{"date-parts":[[2003,3,10]],"date-time":"2003-03-10T09:50:00Z","timestamp":1047289800000},"page":"441-446","source":"Crossref","is-referenced-by-count":28,"title":["Effect of delayed supine positioning after induction of spinal anaesthesia for caesarean section"],"prefix":"10.1111","volume":"46","author":[{"given":"F.","family":"K\u00f8hler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. F.","family":"S\u00f8rensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. S.","family":"Helbo\u2010Hansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,4,19]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004311-199432020-00010"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/75.3.257"},{"key":"e_1_2_6_4_2","first-page":"175","article-title":"Neonatal wellbeing after elective caesarean delivery with general, spinal, and epidural anaesthesia","volume":"10","author":"Ratcliffe FM","year":"1993","journal-title":"Eur J Anaesthesiol"},{"key":"e_1_2_6_5_2","first-page":"610","article-title":"Fetal acid\u2010base state following spinal or epidural anaesthesia for cesarean section","volume":"56","author":"Caritis SN","year":"1980","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/68.1.54"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199504000-00009"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365517909108835"},{"key":"e_1_2_6_9_2","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/0002-9378(68)90035-5","article-title":"The influence of inferior vena cava compression on the level of spinal anesthesia","volume":"101","author":"Barclay DL","year":"1968","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1987.tb02631.x"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/77.3.352"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/69.5.457"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199711000-00024"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-199809000-00023"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4471-0435-3_22"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-198666020-00013"},{"issue":"1","key":"e_1_2_6_17_2","first-page":"A534","article-title":"Effect of injection rate on hypotension associated with spinal anaesthesia for caesarean section (Abstract)","volume":"82","author":"Simon L","year":"1999","journal-title":"Br J Anaesth"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1986.tb12913.x"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1995.tb04620.x"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03010097"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-289X(99)80104-6"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1399-6576.2002.460419.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1399-6576.2002.460419.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1034\/j.1399-6576.2002.460419.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T06:33:49Z","timestamp":1697524429000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1034\/j.1399-6576.2002.460419.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,4]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2002,4]]}},"alternative-id":["10.1034\/j.1399-6576.2002.460419.x"],"URL":"https:\/\/doi.org\/10.1034\/j.1399-6576.2002.460419.x","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,4]]}}}