{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T18:50:08Z","timestamp":1784400608672,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2003,4,23]],"date-time":"2003-04-23T00:00:00Z","timestamp":1051056000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2003,4,23]],"date-time":"2003-04-23T00:00:00Z","timestamp":1051056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,5]]},"DOI":"10.1034\/j.1600-0404.2003.02098.x","type":"journal-article","created":{"date-parts":[[2004,12,18]],"date-time":"2004-12-18T22:51:35Z","timestamp":1103410295000},"page":"318-323","source":"Crossref","is-referenced-by-count":28,"title":["Quantification of regional glial fibrillary acidic protein levels in Alzheimer's disease"],"prefix":"10.1155","volume":"107","author":[{"given":"G. W.","family":"Ross","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. P.","family":"O'Callaghan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. S.","family":"Sharp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Petrovitch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. B.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. D.","family":"Abbott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. J.","family":"Launer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. J.","family":"Foley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. M.","family":"Burchfiel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Hardman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. R.","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,4,23]]},"reference":[{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB1|cit2","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/0006-8993(90)91526-M","article-title":"Characterization of the origins of astrocyte response to injury using the dopaminergic neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine","volume":"521","author":"O'Callaghan","year":"1990","journal-title":"Brain Research"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB2|cit3","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1749-6632.1993.tb18299.x","article-title":"Quantitative features of reactive gliosis following toxicant-induced damage of the CNS","volume":"679","author":"O'Callaghan","year":"1993","journal-title":"Ann N Y Acad Sci"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB3|cit4","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/0014-4886(95)90022-5","article-title":"Early association of reactive astrocytes with seniles plaques in Alzheimer's disease","volume":"132","author":"Pike","year":"1995","journal-title":"Exp Neurol"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB4|cit5","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0304-3940(93)90048-P","article-title":"Alterations of glial fibrillary acidic protein mRNA level in the aging brain and in senile dementia of the Alzheimer type","volume":"151","author":"Le Prince","year":"1993","journal-title":"Neuroscience Lett"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB5|cit6","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0197-4580(91)90056-P","article-title":"Age-related changes in glial fibrillary acidic protein mRNA in the mouse brain","volume":"12","author":"Goss","year":"1991","journal-title":"Neurobiol Aging"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB6|cit7","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF00308809","article-title":"Neuropathological staging of Alzheimer related changes","volume":"82","author":"Braak","year":"1991","journal-title":"Acta Neuropathol"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB7|cit8","volume-title":"The honolulu heart program: an epidemiological study of coronary heart disease and stroke","author":"Kagan","year":"1996"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB8|cit9","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1093\/oxfordjournals.aje.a112185","article-title":"Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: introduction","volume":"102","author":"Syme","year":"1975","journal-title":"Am J Epidemiol"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB9|cit10","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1001\/jama.1996.03540120033030","article-title":"Prevalence of dementia in older Japanese-American men in Hawaii: the Honolulu-Asia Aging Study","volume":"276","author":"White","year":"1996","journal-title":"JAMA"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB10|cit11","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1017\/S1041610294001602","article-title":"A practical test for cross-cultural epidemiological studies of dementia","volume":"6","author":"Teng","year":"1994","journal-title":"Int Psychogeriatr"},{"issue":"Suppl. 1","key":"10.1034\/j.1600-0404.2003.02098.x-BIB11|cit12","first-page":":171","article-title":"Estimation of the sensitivity and specificity of a dementia screening test in a population-based survey","volume":"15","author":"White","year":"1994","journal-title":"Neurobiol Aging"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB12|cit13","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1212\/WNL.39.9.1159","article-title":"The Consortium to establish a registry for Alzheimer's disease (CERAD), part 1: clinical and neuropsychological assessment of Alzheimer's disease","volume":"39","author":"Morris","year":"1989","journal-title":"Neurology"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB13|cit14","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1001\/archneur.1991.00530150046016","article-title":"Detection of abnormal memory decline in mild cases of Alzheimer's disease using CERAD neuropsychological measures","volume":"48","author":"Welsh","year":"1991","journal-title":"Arch Neurol"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB14|cit15","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association.","year":"1987"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB15|cit16","first-page":"87","article-title":"Mild senile dementia of the Alzheimer's type: diagnostic criteria and natural history","volume":"55","author":"Berg","year":"1988","journal-title":"Mt Sinai J Med"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB16|cit17","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1212\/WNL.34.7.939","article-title":"Clinical diagnosis of Alzheimer's disease. Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services task force on Alzheimer's disease","volume":"34","author":"McKhann","year":"1984","journal-title":"Neurology"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB17|cit18","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1212\/WNL.49.4.1175","article-title":"Microscope field size and the neuropathologic criteria for Alzheimer's disease","volume":"49","author":"Petrovitch","year":"1997","journal-title":"Neurology"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB18|cit19","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/0892-0362(91)90073-6","article-title":"Quantification of glial fibrillary acidic protein: comparison of slot-immunobinding assays with a novel sandwich ELISA","volume":"13","author":"O'Callaghan","year":"1991","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB19|cit20","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1523\/JNEUROSCI.07-04-00931.1987","article-title":"Quantitative changes in the synaptic vesicle proteins synapsin I and p38 and the astrocyte-specific protein glial fibrillary acidic protein are associated with chemical-induced injury to the rat central nervous system","volume":"7","author":"Brock","year":"1987","journal-title":"J Neurosci"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB20|cit21","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1006\/abio.1999.4260","article-title":"Quantitative immunoblots of proteins resolved from brain homogenates: underestimation of specific protein concentration and of treatment effects","volume":"274","author":"O'Callaghan","year":"1999","journal-title":"Anal Biochem"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB21|cit22","volume-title":"Fundamentals of biostatistics.","author":"Rosner","year":"2000"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB22|cit23","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/glia.440020605","article-title":"Patterns of gliosis in Alzheimer's disease and aging cerebrum","volume":"2","author":"Beach","year":"1989","journal-title":"Glia"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB23|cit24","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/0014-4886(91)90115-S","article-title":"Astrocyte hypertrophy in the Alzheimer's disease hippocampal formation","volume":"112","author":"Vijayan","year":"1991","journal-title":"Exp Neurol"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB24|cit25","first-page":"35","article-title":"Studies in Alzheimer's disease","volume":"4","author":"Kumar","year":"1991","journal-title":"Neuropsychopharmacology"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB25|cit26","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0197-4580(88)80028-9","article-title":"PET\/dementia: an update","volume":"9","author":"Benson","year":"1988","journal-title":"Neurobiol Aging"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB26|cit27","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1093\/brain\/122.8.1519","article-title":"Neocortical and hippocampal glucose hypometabolism following neurotoxic lesions of the entorhinal and perirhinal cortices in the non-human primate as shown by PET. Implications for Alzheimer's disease","volume":"122","author":"Meguro","year":"1999","journal-title":"Brain"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB27|cit28","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/0197-4580(93)90100-P","article-title":"GFAP mRNA increases with age in rat and human brain","volume":"14","author":"Nichols","year":"1993","journal-title":"Neurobiol Aging"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB28|cit29","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0165-0270(94)90011-6","article-title":"A sensitive ELISA for glial fibrillary acidic protein: application in CSF of adults","volume":"51","author":"Rosengren","year":"1994","journal-title":"J Neuroscience Meth"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB29|cit30","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/0166-2236(96)10049-7","article-title":"Microglia: a sensor for pathological events in the CNS","volume":"19","author":"Kreutzberg","year":"1996","journal-title":"Trends Neurosci"},{"key":"10.1034\/j.1600-0404.2003.02098.x-BIB30|cit31","doi-asserted-by":"crossref","unstructured":"Eng LF Lee YL. 1995 650 67","DOI":"10.1049\/cp:19951119"}],"container-title":["Acta Neurologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1600-0404.2003.02098.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1600-0404.2003.02098.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1034\/j.1600-0404.2003.02098.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,21]],"date-time":"2024-12-21T12:56:20Z","timestamp":1734785780000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1034\/j.1600-0404.2003.02098.x"}},"subtitle":["<b>GFAP levels in Alzheimer's disease<\/b>"],"short-title":[],"issued":{"date-parts":[[2003,4,23]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2003,5]]}},"URL":"https:\/\/doi.org\/10.1034\/j.1600-0404.2003.02098.x","archive":["Portico"],"relation":{},"ISSN":["0001-6314"],"issn-type":[{"value":"0001-6314","type":"print"}],"subject":[],"published":{"date-parts":[[2003,4,23]]}}}