{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T05:18:38Z","timestamp":1788412718784,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2002,6,6]],"date-time":"2002-06-06T00:00:00Z","timestamp":1023321600000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Ophthalmologica Scandinavica"],"published-print":{"date-parts":[[2002,6]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title><jats:p><jats:bold>Purpose:\u2002<\/jats:bold> To evaluate the outcome, long\u2010term results and contributing prognostic factors of trabeculectomy in terms of intraocular pressure (IOP) and to compare the results in primary open\u2010angle glaucoma (POAG) and exfoliation glaucoma (EG).<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> This study involved retrospective evaluation of 138 consecutive patients (138 eyes) with either POAG or EG. All patients had undergone primary trabeculectomy performed by the same surgeon between November 1994 and August 1996. Only one eye per patient was included. Operations performed with the use of antimetabolites were excluded. All patients were aged over 40\u2003years and were white. Follow\u2010up for all subjects lasted at least 2\u2003years. Successful control of IOP was defined as achieving IOP\u2003\u2264\u200321\u2003mmHg without medication (complete success) or with a single topical medication (qualified success). Success rates were determined using the Kaplan\u2010Meier survival curve, and risk factors were analysed with proportional hazards regression.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> According to the Kaplan\u2010Meier survival curve, success rates (complete or qualified) were 82% at 1\u2003year, 70% at 2\u2003years, 64% at 3\u2003years and 52% at 4\u2003years. A total of 63% were complete successes at 1\u2003year, 54% at 2\u2003years, 45% at 3\u2003years and 40% at 4\u2003years. Complete success rates were significantly better in the POAG group than in the EG group. Proportional hazards regression analysis showed that the presence of EG and early postoperative IOP\u2003&gt;\u200330\u2003mmHg decreased the possibility of complete success, while a cataract operation performed during follow\u2010up improved it.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> The IOP\u2010reducing effect of trabeculectomy decreases gradually. After 4\u2003years, 52% of operated eyes had IOP\u2003\u2264\u200321\u2003mmHg with or without a single topical medication. Diagnosis of EG implied a worse long\u2010term outcome for trabeculectomy in terms of IOP.<\/jats:p>","DOI":"10.1034\/j.1600-0420.2002.800307.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T03:18:58Z","timestamp":1047352738000},"page":"267-271","source":"Crossref","is-referenced-by-count":80,"title":["Long\u2010term outcome of trabeculectomy in terms of intraocular pressure"],"prefix":"10.1111","volume":"80","author":[{"given":"Pia","family":"Ehrnrooth","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilkka","family":"Lehto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e4ivi","family":"Puska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Laatikainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,3,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1992.tb08570.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1994.01090230060021"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(79)90559-2"},{"key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"637","DOI":"10.3928\/1542-8877-19990901-07","article-title":"Primary trabeculectomy in young adults: long\u2010term clinical results and factors influencing the outcome","volume":"30","author":"Jacobi PC","year":"1999","journal-title":"Ophthalmic Surg Lasers"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1977.tb06094.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1990.01070130045027"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.83.7.814"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.65.11.790"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(95)30796-8"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.83.3.305"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(98)00290-6"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1034715"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(70)93414-8"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1991.tb02021.x"},{"key":"e_1_2_6_16_1","first-page":"249","article-title":"Filtering blebs: Follow up of trabeculectomy","volume":"24","author":"Vesti E","year":"1993","journal-title":"Ophthalmic Surg"},{"key":"e_1_2_6_17_1","doi-asserted-by":"crossref","first-page":"128","DOI":"10.3928\/1542-8877-19970201-08","article-title":"A review of the outcome of trabeculectomy in open\u2010angle glaucoma","volume":"28","author":"Vesti E","year":"1997","journal-title":"Ophthalmic Surg Lasers"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(81)35051-9"}],"container-title":["Acta Ophthalmologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1600-0420.2002.800307.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1600-0420.2002.800307.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1034\/j.1600-0420.2002.800307.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T09:49:34Z","timestamp":1697536174000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1034\/j.1600-0420.2002.800307.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,6]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2002,6]]}},"alternative-id":["10.1034\/j.1600-0420.2002.800307.x"],"URL":"https:\/\/doi.org\/10.1034\/j.1600-0420.2002.800307.x","archive":["Portico"],"relation":{},"ISSN":["1395-3907","1600-0420"],"issn-type":[{"value":"1395-3907","type":"print"},{"value":"1600-0420","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,6]]}}}