{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T22:10:15Z","timestamp":1697580615251},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2002,10,17]],"date-time":"2002-10-17T00:00:00Z","timestamp":1034812800000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Ophthalmologica Scandinavica"],"published-print":{"date-parts":[[2002,10]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title><jats:p><jats:bold>Purpose:\u2002<\/jats:bold> To present a case of ossification of the eyelid, episclera and orbit in a patient with pseudo\u2010pseudohypoparathyroidism (pPHP).<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> A 20\u2010year\u2010old woman diagnosed with pseudo\u2010pseudohypoparathyroidism underwent clinical and histopathological examination of calcified plaques of the right eyelid and orbit. The patient presented with a round face, tousled short hair and retarded speech. She had been diagnosed with pPHP at 3\u2003years of age. During her first decade, calcified plaques developed in the right eyelid and orbit. Gradually, she developed horizontal diplopia, pseudo\u2010ptosis and periorbital pain. Vertical eye movements were reduced to 10\u2003mm, although levator function remained intact. Computer tomography scans of the orbit showed three separate dense structures. Radiographic findings also showed bilateral shortening of the fourth metacarpus and a calcified subcutaneous plaque in the left thigh. The patient's blood status revealed an elevated level of thyroid stimulating hormone, but was otherwise normal. The patient was treated with eltroxin and shortly afterwards regained normal hair and normal speech function.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> The calcified structures were removed surgically and almost normal eye movements were re\u2010established. Histological examination of the excised tissue demonstrated bone formation.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> This is the first reported case of ossification of the eyelid and orbit in a patient with pseudo\u2010pseudohypoparathyroidism.<\/jats:p>","DOI":"10.1034\/j.1600-0420.2002.800516.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T03:19:41Z","timestamp":1047352781000},"page":"543-545","source":"Crossref","is-referenced-by-count":3,"title":["Primary palpebral and orbital ossification in pseudo\u2010pseudohypoparathyroidism"],"prefix":"10.1111","volume":"80","author":[{"given":"Stefan","family":"Klauber","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steffen","family":"Heegaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Ulrik","family":"Prause","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,3,12]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"922","article-title":"Pseudohypoparathyroidism, an example of Seabright\u2013Bantam Syndrome","volume":"30","author":"Albright F","year":"1942","journal-title":"Endocrinology"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.104.6.643"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.30.2.101"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320110104"},{"key":"e_1_2_4_6_1","first-page":"1140","volume-title":"Endocrinology","author":"Levine MA","year":"2001"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0888-7543(91)90164-A"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1992.tb00318.x"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0026-0495(75)90134-1"},{"key":"e_1_2_4_10_1","first-page":"618","article-title":"Pseudo\u2010pseudohypoparatyreoidisme og hypotyreoidisme hos et tre \u00e5r gammelt barn","volume":"147","author":"Storm K","year":"1985","journal-title":"Ugeskr Laeger"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.84.9.3254"}],"container-title":["Acta Ophthalmologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1600-0420.2002.800516.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1600-0420.2002.800516.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1034\/j.1600-0420.2002.800516.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T21:35:03Z","timestamp":1697578503000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1034\/j.1600-0420.2002.800516.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,10]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,10]]}},"alternative-id":["10.1034\/j.1600-0420.2002.800516.x"],"URL":"https:\/\/doi.org\/10.1034\/j.1600-0420.2002.800516.x","archive":["Portico"],"relation":{},"ISSN":["1395-3907","1600-0420"],"issn-type":[{"value":"1395-3907","type":"print"},{"value":"1600-0420","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,10]]}}}