{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T10:08:29Z","timestamp":1776334109323,"version":"3.51.2"},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2002,12,17]],"date-time":"2002-12-17T00:00:00Z","timestamp":1040083200000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Ophthalmologica Scandinavica"],"published-print":{"date-parts":[[2002,12]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title><jats:p><jats:bold>Purpose:\u2002<\/jats:bold> There is increasing evidence that the common respiratory human pathogen <jats:italic>Chlamydia pneumoniae<\/jats:italic> has a causative role in atherosclerosis. We investigated the association of this pathogen with acute central retinal artery occlusion (CRAO).<\/jats:p><jats:p><jats:bold>Patients and Methods:\u2002<\/jats:bold> Sera of 14 consecutive patients with CRAO and of 14 age\u2010 and sex\u2010matched control subjects were examined. Antibodies against chlamydial lipopolysaccharide (LPS) and outer membrane proteins of <jats:italic>C.\u2003pneumoniae<\/jats:italic> were determined by an enzyme\u2010linked immunosorbent assay (ELISA).<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> In the CRAO group, seven patients (50%) were found to be IgA positive, 12 (86%) were IgG positive and one (7%) was IgM positive for chlamydial LPS antibodies. In the control group 36%, 79% and 14% were IgA, IgG and IgM positive, respectively. The results showed no significant difference between the groups. In the CRAO group, IgA, IgG and IgM antibodies to <jats:italic>C.\u2003pneumoniae<\/jats:italic> were found in 43%, 79% and 0% of subjects, respectively. These findings did not differ significantly from those pertaining to matched controls.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> These data do not support an association between acute CRAO and current <jats:italic>C.\u2003pneumoniae<\/jats:italic> infection.<\/jats:p>","DOI":"10.1034\/j.1600-0420.2002.800618.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T03:19:41Z","timestamp":1047352781000},"page":"656-659","source":"Crossref","is-referenced-by-count":4,"title":["Chlamydia pneumoniae in central retinal artery occlusion"],"prefix":"10.1111","volume":"80","author":[{"given":"Pia 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