{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T22:17:36Z","timestamp":1790979456977,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2003,1,13]],"date-time":"2003-01-13T00:00:00Z","timestamp":1042416000000},"content-version":"vor","delay-in-days":257,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2002,5]]},"abstract":"<jats:title>Structured Abstract<\/jats:title><jats:p> <jats:italic>Authors<\/jats:italic>\u2013 Bondarets N, Jones RM, McDonald F.<\/jats:p><jats:p> <jats:italic>Objective<\/jats:italic>\u2013 To examine the craniofacial growth pattern of patients diagnosed with syndromic ectodermal dysplasia.<\/jats:p><jats:p> <jats:italic>&gt;Design<\/jats:italic>\u2013 Mixed longitudinal analysis of lateral cephalograms.<\/jats:p><jats:p> <jats:italic>Setting<\/jats:italic>\u2013 The data were analysed using a multilevel modelling technique with the MLwiN application software and the results presented numerically and graphically.<\/jats:p><jats:p> <jats:italic>Sample Population<\/jats:italic>\u2013 All 61 subjects had severe hypodontia with the number of absent teeth (excluding third molars) ranging from 6 to 28 (mean=15.4). At presentation the subjects had a mean age of 133\u2003months and were followed longitudinally for between one and five subsequent occasions (mean 2.66 occasions; mean age at completion of observation 207\u2003months).<\/jats:p><jats:p> <jats:italic>Outcome Measures<\/jats:italic>\u2013 Lateral cephalograms taken at each visit.<\/jats:p><jats:p> <jats:italic>Experimental Variables<\/jats:italic>\u2013 Analysis of four angular measurements and four linear measurements, together with one calculated ratio.<\/jats:p><jats:p> <jats:italic>Results<\/jats:italic>\u2013 Growth curves are presented showing the trends of craniofacial growth.<\/jats:p><jats:p> <jats:italic>Conclusions<\/jats:italic>\u2013 The most significant findings were for a universal tendency for the individuals to undergo a change in sagittal relationship of the jaws, becoming markedly more Class III with time. We have also demonstrated a significant difference in growth between the anterior and posterior face heights indicating that the subjects have a tendency to an anterior growth rotation.<\/jats:p>","DOI":"10.1034\/j.1600-0544.2002.01159.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T15:45:05Z","timestamp":1047483905000},"page":"71-84","source":"Crossref","is-referenced-by-count":32,"title":["Analysis of facial growth in subjects with syndromic ectodermal dysplasia: a longitudinal analysis"],"prefix":"10.1111","volume":"5","author":[{"given":"N","family":"Bondarets","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RM","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,1,13]]},"reference":[{"key":"e_1_2_6_2_2","unstructured":"GorlinRJ.Syndromes of the Head and Neck. 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