{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T04:56:20Z","timestamp":1784696180526,"version":"3.55.0"},"reference-count":4,"publisher":"Wiley","issue":"s1","license":[{"start":{"date-parts":[[2003,8,11]],"date-time":"2003-08-11T00:00:00Z","timestamp":1060560000000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2003,8]]},"abstract":"Structured Abstract<\/jats:title> \n Authors<\/jats:italic>\u2013<\/jats:bold> Nakano H, Watahiki J, Kubota M, Maki K, Shibasaki Y, Hatcher D, Miller AJ<\/jats:p> \n Objectives \u2013<\/jats:italic>\n <\/jats:bold>To investigate the influence of forced lateral bite on mandibular growth, micro X\u2010ray computed tomography (CT) was used for the purpose evaluating condylar cartilage and cancellous bone formation in 10 male Wister rats (3\u2003weeks of age).<\/jats:p> \n Settings and sample population \u2013<\/jats:italic>\n <\/jats:bold>The rats were divided into two groups \u2013 experimental and control. In experimental group, an inclined crown was cemented onto the maxillary incisors to produce 2.5\u2003mm shift toward the left side during mastication. Right\u2013left differences in whole mandibular length, mandibular height, condylar size, trabecular structure of the condylar head and three\u2010dimensional (3\u2010D) finite element analysis were assessed using 3\u2010D images reconstructed from micro X\u2010ray CT scans when the mice had reached 21\u2003weeks.<\/jats:p> \n Measurements and Results \u2013<\/jats:italic>\n <\/jats:bold>Asymmetrical growth was found in the experimental group, in which the left condylar head became thicker and shorter than the right condylar head during development. When comparing the left and right condyles of the experimental animals, histomorphometric analysis from micro X\u2010ray CT showed that the bone volume (BV) of the cancellous bone, the surface area of the cancellous bone (BS), the BS\/BV ratio, the BV fraction (BV\/TV), and the trabecular thickness and trabecular number were less for the right condyle than for the left condyle.<\/jats:p> \n Conclusions \u2013<\/jats:italic>\n <\/jats:bold>These findings suggested that artificial changes in the mastication do influence the growth of condylar head, condylar bone trabecular structure, and mineralization.<\/jats:p>","DOI":"10.1034\/j.1600-0544.2003.252.x","type":"journal-article","created":{"date-parts":[[2004,11,15]],"date-time":"2004-11-15T13:19:39Z","timestamp":1100524779000},"page":"168-172","source":"Crossref","is-referenced-by-count":24,"title":["Micro X\u2010ray computed tomography analysis for the evaluation of asymmetrical condylar growth in the rat"],"prefix":"10.1111","volume":"6","author":[{"given":"H","family":"Nakano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Watahiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Kubota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Maki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Shibasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Hatcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AJ","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,8,11]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"339","article-title":"Effect of lateral deviation of mandibular position on craniomandibular growth","volume":"69","author":"Kapila S","year":"1990","journal-title":"J Dent Res"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/23.3.217"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1089"},{"key":"e_1_2_5_5_2","doi-asserted-by":"crossref","first-page":"413","DOI":"10.3233\/THC-1998-65-613","article-title":"Assessment of cancellous bone mechanical properties from micro\u2010FE models based on micro\u2010CT, pQCT and MR images","volume":"6","author":"Van Rietbergen B","year":"1998","journal-title":"Technol Health Care"}],"container-title":["Orthodontics & Craniofacial Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1600-0544.2003.252.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1600-0544.2003.252.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1034\/j.1600-0544.2003.252.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T01:04:51Z","timestamp":1695776691000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1034\/j.1600-0544.2003.252.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,8]]},"references-count":4,"journal-issue":{"issue":"s1","published-print":{"date-parts":[[2003,8]]}},"alternative-id":["10.1034\/j.1600-0544.2003.252.x"],"URL":"https:\/\/doi.org\/10.1034\/j.1600-0544.2003.252.x","archive":["Portico"],"relation":{},"ISSN":["1601-6335","1601-6343"],"issn-type":[{"value":"1601-6335","type":"print"},{"value":"1601-6343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,8]]}}}