{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T01:04:56Z","timestamp":1783559096662,"version":"3.55.0"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2002,5,23]],"date-time":"2002-05-23T00:00:00Z","timestamp":1022112000000},"content-version":"vor","delay-in-days":52,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2002,4]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Trichotillomania (TM) is a chronic disorder in which patients traumatically remove their own hair in a bizarre pattern. TM histopathological findings are not well defined.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Twenty\u2010eight scalp biopsies of TM were reviewed. Multiple vertical sections and special stains were used to evaluate the specimens. Twenty\u2010six patients (24 female, 2 male) were in the cohort, 2 patients had 2 sets of biopsies.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Age range was 13^78 years (mean 41 years), most of them presented with chronic TM. Specific histological findings included trichomalacia (57%) and pigmented casts (46%). Non\u2010specific histological findings included: follicular plugging (96%), decreased number of follicles (96%), reversed anagen:telogen ratio (86%), decreased number of sebaceous glands (68%), melanoderma (68%), increased number of fibrous tracts (64%) and vellus hairs (57%), superficial dermal inflammation (57%), evidence of hemorrhage (18%) and presence of hair granulomas (18%).<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> Even though TM is often a disease of the young people, middle aged and elderly patients with TM have more often a biopsy to confirm the diagnosis. This paper suggests diagnostic criteria for TM. Specific histological findings and clinical suspicion of TM were considered major criteria, while the non\u2010specific histological findings were considered minor diagnostic criteria for TM.<\/jats:p>","DOI":"10.1034\/j.1600-0560.2002.290403.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T13:54:46Z","timestamp":1047390886000},"page":"207-214","source":"Crossref","is-referenced-by-count":30,"title":["The combined utilization of clinical and histological findings in the diagnosis of trichotillomania"],"prefix":"10.1111","volume":"29","author":[{"given":"Wilma","family":"Bergfeld","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiane","family":"Mulinari\u2010Brenner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"McCarron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen","family":"Embi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,5,23]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1999.00006.x"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(05)70408-9"},{"key":"e_1_2_7_4_2","first-page":"440","article-title":"Alop\u00e9cie par grattage (trichomanie out trichotillomanie)","volume":"10","author":"Hallopeau H.","year":"1889","journal-title":"Ann Dermatol Syphiligr (Paris)"},{"key":"e_1_2_7_5_2","first-page":"289","article-title":"Trichotillomania","volume":"53","author":"Schneider D","year":"1994","journal-title":"Cutis"},{"key":"e_1_2_7_6_2","first-page":"67","article-title":"Trichotillomania in connection with alopecia areata","volume":"58","author":"Tr\u00fceb R","year":"1996","journal-title":"Cutis"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(90)70186-L"},{"key":"e_1_2_7_8_2","first-page":"618","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association.","year":"1994"},{"key":"e_1_2_7_9_2","first-page":"301","article-title":"Alopecia: histologic changes","volume":"4","author":"Bergfeld W.","year":"1989","journal-title":"Adv Dermatol"},{"key":"e_1_2_7_10_2","first-page":"201","volume-title":"Textbook of Dermatopathology","author":"Whitting DA","year":"1998"},{"key":"e_1_2_7_11_2","first-page":"647","volume-title":"Dermatologic Surgery","author":"Bergfeld WF","year":"1996"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000256114"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1600-0560.2002.290403.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1600-0560.2002.290403.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1034\/j.1600-0560.2002.290403.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T06:38:07Z","timestamp":1697524687000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1034\/j.1600-0560.2002.290403.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,4]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2002,4]]}},"alternative-id":["10.1034\/j.1600-0560.2002.290403.x"],"URL":"https:\/\/doi.org\/10.1034\/j.1600-0560.2002.290403.x","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,4]]}}}