{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T20:31:51Z","timestamp":1762374711201},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2002,9,13]],"date-time":"2002-09-13T00:00:00Z","timestamp":1031875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Periodontal Research"],"published-print":{"date-parts":[[2002,10]]},"abstract":"<jats:p>The terms \u2018early onset periodontitis\u2019 (EOP) and \u2018juvenile periodontitis\u2019 (JP) were replaced by that of \u2018aggressive periodontitis\u2019 in a recent international workshop for the classification of periodontal diseases and conditions. The chief etiologic agent for aggressive periodontitis is considered to be <jats:italic>Actinobacillus actinomycetemcomitans<\/jats:italic> in localized juvenile periodontitis. <jats:italic>Porphyromonas gingivalis<\/jats:italic> is also mentioned as the etiologic agent of the aggressive periodontitis, although to date its role remains questionable. This communication describes three cases of aggressive periodontitis found to be associated with <jats:italic>P.\u2003gingivalis<\/jats:italic> but not <jats:italic>A.\u2003actinomycetemcomitans<\/jats:italic> by polymerase chain reaction (PCR) and enzyme\u2010linked immunosorbent assay (ELISA). Our findings clarify the role of <jats:italic>P.\u2003gingivalis<\/jats:italic> as an etiologic agent in this type of periodontitis and confirm its inclusion in the current definition of aggressive periodontitis.<\/jats:p>","DOI":"10.1034\/j.1600-0765.2002.01613.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T08:55:51Z","timestamp":1047459351000},"page":"324-332","source":"Crossref","is-referenced-by-count":17,"title":["Three case reports of aggressive periodontitis associated with <i>Porphyromonas gingivalis<\/i> in younger patients"],"prefix":"10.1111","volume":"37","author":[{"given":"Isao","family":"Ishikawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoko","family":"Kawashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Oda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takanori","family":"Iwata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichi","family":"Arakawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,9,13]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1902\/annals.1999.4.1.1","article-title":"The new classification for periodontal diseases and conditions","volume":"4","author":"The American Academy of Periodontology.","year":"1999","journal-title":"Ann Periodontol"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1998.69.7.828"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1995.tb00798.x"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/10454411910020020301"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.66.9.4474-4483.1998"},{"key":"e_1_2_7_7_2","doi-asserted-by":"crossref","first-page":"5008","DOI":"10.1128\/IAI.66.10.5008-5019.1998","article-title":"The cell cycle\u2010specific growth\u2010inhibitory factor_produced by Actinobacillus actinomycetemcomitans","volume":"66","author":"Sugai S","year":"1998","journal-title":"Infect Immun"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.66.12.5980-5987.1998"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1986.57.9.537"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1983.54.12.707"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1987.tb00996.x"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1994.65.4.364"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00915793"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1985.tb00446.x"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1985.tb01382.x"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1986.57.2.94"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1993.tb00379.x"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1988.59.6.373"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2000.027008597.x"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1998.tb02419.x"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1990.tb00225.x"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1996.tb00541.x"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1990.tb00030.x"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1999.70.6.574"}],"container-title":["Journal of Periodontal Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1600-0765.2002.01613.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1034%2Fj.1600-0765.2002.01613.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1034\/j.1600-0765.2002.01613.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T01:18:26Z","timestamp":1697505506000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1034\/j.1600-0765.2002.01613.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,9,13]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,10]]}},"alternative-id":["10.1034\/j.1600-0765.2002.01613.x"],"URL":"https:\/\/doi.org\/10.1034\/j.1600-0765.2002.01613.x","archive":["Portico"],"relation":{},"ISSN":["0022-3484","1600-0765"],"issn-type":[{"value":"0022-3484","type":"print"},{"value":"1600-0765","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,9,13]]}}}