{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:46:33Z","timestamp":1791161193773,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2003,1,28]],"date-time":"2003-01-28T00:00:00Z","timestamp":1043712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Periodontal Research"],"published-print":{"date-parts":[[2003,2]]},"abstract":"<jats:p>The aim of the present study was to evaluate the influence of membrane exposure on guided tissue regeneration (GTR). Thirty patients with 2\u2010wall or 3\u2010wall intraosseous defects were treated with GTR. Periodontal index, gingival index, bleeding on probing, probing depth, clinical attachment level and recession were assessed at the baseline examination, as well as immediately prior to and six months after GTR. The numbers of <jats:italic>Porphyromonas gingivalis<\/jats:italic> and <jats:italic>Actinobacillus actinomycetemcomitans<\/jats:italic> on the retrieved expanded polytetrafluoroethylene (e\u2010PTFE) membranes were assessed using polymerase chain reaction. The results showed that 26.3% of the membrane exposure sites had zero attachment gain. The membrane exposure sites tended to achieve a smaller clinical attachment gain and had significantly greater marginal tissue recession (\u200a<jats:italic>p<\/jats:italic>\u2003=\u20030.006). In addition, the exposed membranes harbored significantly more <jats:italic>A.\u2003actinomycetemcomitans<\/jats:italic> than the non\u2010exposed membranes (<jats:italic>p<\/jats:italic>\u2003=\u20030.029). In conclusion, membrane exposure resulted in a poor GTR outcome. The amount of <jats:italic>A.\u2003actinomycetemcomitans<\/jats:italic> on the exposed membrane may be a major contributing factor to the outcome of GTR.<\/jats:p>","DOI":"10.1034\/j.1600-0765.2003.01641.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T08:56:15Z","timestamp":1047459375000},"page":"57-63","source":"Crossref","is-referenced-by-count":43,"title":["The influence of membrane exposure on the outcomes of guided tissue regeneration: clinical and microbiological aspects"],"prefix":"10.1111","volume":"38","author":[{"given":"Li\u2010Jane","family":"Ling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan\u2010Ling","family":"Hung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching\u2010Fang","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yen\u2010Ting","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai\u2010Ming","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,1,28]]},"reference":[{"key":"e_1_2_12_2_2","first-page":"8","article-title":"New attachment after treatment with root isolation procedures: report for treated Class III and Class II furcations and vertical osseous defects","volume":"8","author":"Becker W","year":"1988","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1986.tb00854.x"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1988.tb01578.x"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1991.62.4.264"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1992.63.6.554"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1991.62.6.353"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1992.63.5.431"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1992.63.3.215"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1993.64.11s.1138"},{"key":"e_1_2_12_11_2","first-page":"166","article-title":"Guided tissue regeneration: biologic rationale, surgical technique, and clinical results","volume":"13","author":"Caffesse RG","year":"1992","journal-title":"Compendium"},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1990.61.8.515"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1994.tb00305.x"},{"key":"e_1_2_12_14_2","first-page":"8","article-title":"Combined osseous composite grafting, root conditioning, and guided tissue regeneration","volume":"8","author":"Schallhorn RG","year":"1988","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_12_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1995.tb00151.x"},{"key":"e_1_2_12_16_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1993.64.3.162"},{"key":"e_1_2_12_17_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1993.64.11s.1171"},{"key":"e_1_2_12_18_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1994.65.2.154"},{"key":"e_1_2_12_19_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1992.63.12.974"},{"key":"e_1_2_12_20_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016356408993968"},{"key":"e_1_2_12_21_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016356309011240"},{"key":"e_1_2_12_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.28.2.319-323.1990"},{"key":"e_1_2_12_23_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-302X.2001.160608.x"},{"key":"e_1_2_12_24_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1996.67.10.994"},{"key":"e_1_2_12_25_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1996.67.7.694"},{"key":"e_1_2_12_26_2","first-page":"363","article-title":"Postoperative healing complications associated with Gore\u2010Tex periodontal material. 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