{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T23:29:54Z","timestamp":1778542194765,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2002,9,30]],"date-time":"2002-09-30T00:00:00Z","timestamp":1033344000000},"content-version":"vor","delay-in-days":29,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacology &amp; Toxicology"],"published-print":{"date-parts":[[2002,9]]},"abstract":"<jats:p><jats:bold>Abstract:<\/jats:bold> Systemic bleeding due to consumption coagulopathy and thrombocytopenia due to activation of procoagulants is the leading manifestation and cause of death in Russell's viper systemic envenoming. Thrombotic occlusion of the blood vessels is rare in cases of snakebite. In this report, two adult patients with Russell's viper systemic envenoming presented multiple cerebral infarctions, digital gangrenes and ischaemic organs in addition to typical clinical manifestations of bleeding diathesis and renal involvement. Our findings in these two special cases suggest that the venom\u2010induced coagulopathy and endothelium damage, predisposed by toxin\u2010induced vasoconstriction, might be the possible mechanism of multiple thrombotic vascular occlusions in systemic envenoming of Formosan Russell's viper.<\/jats:p>","DOI":"10.1034\/j.1600-0773.2002.910303.x","type":"journal-article","created":{"date-parts":[[2003,3,12]],"date-time":"2003-03-12T18:55:47Z","timestamp":1047495347000},"page":"106-110","source":"Crossref","is-referenced-by-count":33,"title":["Multiple Thrombotic Occlusions of Vessels after Russell's Viper Envenoming"],"prefix":"10.1111","volume":"91","author":[{"given":"Dong\u2010Zong","family":"Hung","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming\u2010Ling","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jou\u2010Fang","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dar\u2010Yu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoei\u2010Yn","family":"Lin\u2010Shiau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,9,30]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.91.3.776"},{"key":"e_1_2_4_3_1","first-page":"95","article-title":"Middle cerebral occlusion following Russell's viper bite","volume":"75","author":"Ameratunga B.","year":"1972","journal-title":"J. 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