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T cells are not only confined to the uterus. T cells are also present in <jats:italic>cumulus oophorus<\/jats:italic> and are able to produce LIF and IL\u20104.<\/jats:p><jats:p>CONCLUSIONS:\u2002These findings may provide an initial cue in favor of the possibility that different cytokines produced by T cells acting in concert are required to create a suitable microenvironment for the preimplantation embryo development and for the maintenance of pregnancy. T cells could work in parallel with other cells present in the decidua and <jats:italic>cumulus<\/jats:italic> suggesting a complex network of hormones, cytokines and cells.<\/jats:p>","DOI":"10.1034\/j.1600-0897.2002.01104.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T01:26:47Z","timestamp":1047346007000},"page":"289-294","source":"Crossref","is-referenced-by-count":57,"title":["T\u2010cell Cytokines in Pregnancy"],"prefix":"10.1111","volume":"47","author":[{"given":"MARIE\u2010PIERRE","family":"PICCINNI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,4,25]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.07.040189.001045"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(91)90120-I"},{"key":"e_1_2_7_4_2","doi-asserted-by":"crossref","first-page":"128","DOI":"10.4049\/jimmunol.155.1.128","article-title":"Progesterone favors the development of human T helper cells producing Th2\u2010type cytokines and promotes both IL\u20104 production and membrane CD30 expression in established Th1 cells clones","volume":"155","author":"Piccinni M\u2010P","year":"1995","journal-title":"J Immunol"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-4141(199907)29:07<2241::AID-IMMU2241>3.0.CO;2-E"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02918503"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1042\/bst0280212"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(00)00299-X"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0952-7915(96)80087-2"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0952-7915(94)90081-7"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01541085"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.161.5.2241"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.2.462"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64527-0"},{"key":"e_1_2_7_15_2","doi-asserted-by":"crossref","first-page":"4562","DOI":"10.4049\/jimmunol.151.9.4562","article-title":"Synthesis of T helper 2\u2010type cytokines at maternal\u2013fetal interface","volume":"151","author":"Lin H","year":"1993","journal-title":"J Immunol"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(93)90235-D"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/2006"},{"key":"e_1_2_7_18_2","unstructured":"PiccinniM\u2010P BeloniL LiviC MaggiE ScarselliGF RomagnaniS:The maintenance of pregnancy is associated with predominance of Th2 type\u2010cytokines.InThe Embryo from Gametogenesis to Implantation N Colarcurci A Cardone (eds). 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