{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:05:37Z","timestamp":1761764737198},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"5157","license":[{"start":{"date-parts":[[1968,8,1]],"date-time":"1968-08-01T00:00:00Z","timestamp":-44755200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1968,8]]},"DOI":"10.1038\/219947a0","type":"journal-article","created":{"date-parts":[[2006,7,6]],"date-time":"2006-07-06T10:34:26Z","timestamp":1152182066000},"page":"947-949","source":"Crossref","is-referenced-by-count":18,"title":["Allosteric Transitions of Glutamate Dehydrogenase"],"prefix":"10.1038","volume":"219","author":[{"given":"A. D. B.","family":"MALCOLM","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. K.","family":"RADDA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF219947a0_CR1","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/S0022-2836(66)80078-5","volume":"18","author":"E Appella","year":"1966","unstructured":"Appella, E., and Tomkins, G. M., J. Mol. Biol., 18, 77 (1966).","journal-title":"J. Mol. Biol."},{"key":"BF219947a0_CR2","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1042\/bj0980105","volume":"98","author":"PM Bayley","year":"1966","unstructured":"Bayley, P. M., and Radda, G. K., Biochem. J., 98, 105 (1966).","journal-title":"Biochem. J."},{"key":"BF219947a0_CR3","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/S0021-9258(18)81392-8","volume":"237","author":"J Wolff","year":"1962","unstructured":"Wolff, J., J. Biol. Chem., 237, 236 (1962).","journal-title":"J. Biol. Chem."},{"key":"BF219947a0_CR4","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1016\/0006-3002(62)90204-4","volume":"59","author":"C Frieden","year":"1962","unstructured":"Frieden, C., Biochim. Biophys. Acta, 59, 484 (1962).","journal-title":"Biochim. Biophys. Acta"},{"key":"BF219947a0_CR5","doi-asserted-by":"crossref","first-page":"3652","DOI":"10.1016\/S0021-9258(18)99823-6","volume":"241","author":"RF Colman","year":"1966","unstructured":"Colman, R. F., and Frieden, C., J. Biol. Chem., 241, 3652, 3661 (1966).","journal-title":"J. Biol. Chem."},{"key":"BF219947a0_CR6","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1016\/S0006-291X(67)80014-7","volume":"27","author":"GH Dodd","year":"1967","unstructured":"Dodd, G. H., and Radda, G. K., Biochem. Biophys. Res. Commun., 27, 500 (1967).","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"BF219947a0_CR7","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1016\/S0022-5193(62)80037-X","volume":"3","author":"BR Baker","year":"1962","unstructured":"Baker, B. R., Lee, W. W., and Tong, E., J. Theoret. Biol., 3, 459 (1962).","journal-title":"J. Theoret. Biol."},{"key":"BF219947a0_CR8","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1021\/bi00865a047","volume":"5","author":"DE Koshland, jun","year":"1966","unstructured":"Koshland, jun., D. E., and N\u00e9methy, G., and Filmer, D., Biochemistry, 5, 365 (1966).","journal-title":"Biochemistry"},{"key":"BF219947a0_CR9","doi-asserted-by":"crossref","first-page":"4192","DOI":"10.1016\/S0021-9258(18)95797-2","volume":"242","author":"ME Kirtley","year":"1967","unstructured":"Kirtley, M. E., and Koshland, jun., D. E., J. Biol. Chem., 242, 4192 (1967).","journal-title":"J. Biol. Chem."},{"key":"BF219947a0_CR10","first-page":"5P","volume":"108","author":"GH Dodd","year":"1968","unstructured":"Dodd, G. H., and Radda, G. K., Biochem. J., 108, 5P (1968).","journal-title":"Biochem. J."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/219947a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/219947a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/219947a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T20:17:34Z","timestamp":1638389854000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/219947a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1968,8]]},"references-count":10,"journal-issue":{"issue":"5157","published-print":{"date-parts":[[1968,8]]}},"alternative-id":["BF219947a0"],"URL":"https:\/\/doi.org\/10.1038\/219947a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1968,8]]}}}