{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T07:05:37Z","timestamp":1762067137830},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"5219","license":[{"start":{"date-parts":[[1969,11,1]],"date-time":"1969-11-01T00:00:00Z","timestamp":-5270400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1969,11]]},"DOI":"10.1038\/224609a0","type":"journal-article","created":{"date-parts":[[2006,7,6]],"date-time":"2006-07-06T12:12:05Z","timestamp":1152187925000},"page":"609-610","source":"Crossref","is-referenced-by-count":93,"title":["Cyclic 3\u2032,5\u2032-Adenosine Monophosphate in Human Blood Platelets"],"prefix":"10.1038","volume":"224","author":[{"given":"EDWIN W.","family":"SALZMAN","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LENA L.","family":"NERI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF224609a0_CR1","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1161\/01.CIR.37.2.279","volume":"37","author":"EW Sutherland","year":"1968","unstructured":"Sutherland, E. W., Robison, G. A., and Butcher, R. W., Circulation, 37, 279 (1968).","journal-title":"Circulation"},{"key":"BF224609a0_CR2","first-page":"670","volume":"18","author":"NG Ardlie","year":"1967","unstructured":"Ardlie, N. G., Glew, G., Schultz, B. C., and Schwartz, C. J., Thromb. Diath. Haemorrh., 18, 670 (1967).","journal-title":"Thromb. Diath. Haemorrh."},{"key":"BF224609a0_CR3","first-page":"507","volume":"7","author":"EW Salzman","year":"1962","unstructured":"Salzman, E. W., Thromb. Diath. Haemorrh., 7, 507 (1962).","journal-title":"Thromb. Diath. Haemorrh."},{"key":"BF224609a0_CR4","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1016\/S0021-9258(18)60316-3","volume":"237","author":"RW Butcher","year":"1962","unstructured":"Butcher, R. W., and Sutherland, E. W., J. Biol. Chem., 237, 1244 (1962).","journal-title":"J. Biol. Chem."},{"key":"BF224609a0_CR5","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/0005-2787(68)90321-3","volume":"161","author":"F Honda","year":"1968","unstructured":"Honda, F., and Imamura, H., Biochim. Biophys. Acta, 161, 267 (1968).","journal-title":"Biochim. Biophys. Acta"},{"key":"BF224609a0_CR6","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1038\/200763a0","volume":"200","author":"JR O'Brien","year":"1963","unstructured":"O'Brien, J. R., Nature, 200, 763 (1963).","journal-title":"Nature"},{"key":"BF224609a0_CR7","first-page":"623","volume":"21","author":"EW Sutherland","year":"1965","unstructured":"Sutherland, E. W., Oye, I., and Butcher, R. W., Rec. Progr. Hormone Res., 21, 623 (1965).","journal-title":"Rec. Progr. Hormone Res."},{"key":"BF224609a0_CR8","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1111\/j.1365-2141.1964.tb00681.x","volume":"10","author":"JRA Mitchell","year":"1964","unstructured":"Mitchell, J. R. A., and Sharp, A. A., Brit. J. Haematol., 10, 78 (1964).","journal-title":"Brit. J. Haematol."},{"key":"BF224609a0_CR9","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/S0021-9258(18)69547-X","volume":"235","author":"TE Mansour","year":"1960","unstructured":"Mansour, T. E., Sutherland, E. W., Rall, T. W., and Bueding, E., J. Biol. Chem., 235, 466 (1960).","journal-title":"J. Biol. Chem."},{"key":"BF224609a0_CR10","first-page":"241","volume-title":"Proc. Nobel Symposium","author":"J Kloeze","year":"1966","unstructured":"Kloeze, J., Proc. Nobel Symposium II, 241 (Stockholm, 1966)."},{"key":"BF224609a0_CR11","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1016\/S0021-9258(18)93504-0","volume":"243","author":"RW Butcher","year":"1968","unstructured":"Butcher, R. W., and Baird, C. E., J. Biol. Chem., 243, 1713 (1968).","journal-title":"J. Biol. Chem."},{"key":"BF224609a0_CR12","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1038\/192531a0","volume":"192","author":"A Gaarder","year":"1961","unstructured":"Gaarder, A., Jonsen, J., Laland, S., Hellem, A., and Owren, P. A., Nature, 192, 531 (1961).","journal-title":"Nature"},{"key":"BF224609a0_CR13","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1016\/0003-2697(67)90193-5","volume":"21","author":"GL Pauk","year":"1967","unstructured":"Pauk, G. L., and Reddy, W. J., Anal. Biochem., 21, 298 (1967).","journal-title":"Anal. Biochem."},{"key":"BF224609a0_CR14","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1152\/jappl.1950.3.6.365","volume":"3","author":"G Brecher","year":"1950","unstructured":"Brecher, G., and Cronkite, E. P., J. Appl. Physiol., 3, 365 (1950).","journal-title":"J. Appl. Physiol."},{"key":"BF224609a0_CR15","first-page":"195","volume":"56","author":"K Grette","year":"1962","unstructured":"Grette, K., Acta Physiol. Scand., 56, Suppl. 195 (1962).","journal-title":"Acta Physiol. Scand."},{"key":"BF224609a0_CR16","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1038\/211140a0","volume":"211","author":"DC MacMillan","year":"1966","unstructured":"MacMillan, D. C., Nature, 211, 140 (1966).","journal-title":"Nature"},{"key":"BF224609a0_CR17","doi-asserted-by":"publisher","first-page":"1267","DOI":"10.1152\/ajplegacy.1964.206.6.1267","volume":"206","author":"TH Spaet","year":"1964","unstructured":"Spaet, T. H., and Zucker, M. B., Amer. J. Physiol., 206, 1267 (1964).","journal-title":"Amer. J. Physiol."},{"key":"BF224609a0_CR18","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/0006-291X(69)90277-0","volume":"35","author":"SM Wolfe","year":"1969","unstructured":"Wolfe, S. M., and Shulman, N. R., Biochem. Biophys. Res. Commun., 35, 265 (1969).","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"BF224609a0_CR19","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/S0368-1319(69)80052-9","volume":"9","author":"YH Abdulla","year":"1969","unstructured":"Abdulla, Y. H., J. Athero. Res., 9, 171 (1969).","journal-title":"J. Athero. Res."},{"key":"BF224609a0_CR20","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1016\/0006-291X(69)90368-4","volume":"35","author":"PD Zieve","year":"1969","unstructured":"Zieve, P. D., and Greenough, W. B., Biochem. Biophys. Res. Commun., 35, 462 (1969).","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"BF224609a0_CR21","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1111\/j.2042-7158.1968.tb09709.x","volume":"20","author":"K Rysanek","year":"1968","unstructured":"Rysanek, K., Svehla, C., Spankova, H., and Mljnkova, M., J. Pharm. Pharmac., 20, 155 (1968).","journal-title":"J. Pharm. Pharmac."},{"key":"BF224609a0_CR22","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1016\/0006-3002(62)90475-4","volume":"65","author":"T Posternak","year":"1962","unstructured":"Posternak, T., Sutherland, E. W., and Henion, W. F., Biochim. Biophys. Acta, 65, 558 (1962).","journal-title":"Biochim. Biophys. Acta"},{"key":"BF224609a0_CR23","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1016\/0304-4165(69)90323-7","volume":"177","author":"PE Cryer","year":"1969","unstructured":"Cryer, P. E., Jarett, L., and Kipnis, D. M., Biochim. Biophys. Acta, 177, 586 (1969).","journal-title":"Biochim. Biophys. Acta"}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/224609a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/224609a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/224609a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T19:08:09Z","timestamp":1638385689000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/224609a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,11]]},"references-count":23,"journal-issue":{"issue":"5219","published-print":{"date-parts":[[1969,11]]}},"alternative-id":["BF224609a0"],"URL":"https:\/\/doi.org\/10.1038\/224609a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1969,11]]}}}