{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:09:33Z","timestamp":1791356973962,"version":"4.3.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"6745","license":[{"start":{"date-parts":[[1999,8,1]],"date-time":"1999-08-01T00:00:00Z","timestamp":933465600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1999,8]]},"DOI":"10.1038\/23270","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T04:41:22Z","timestamp":1027658482000},"page":"671-675","source":"Crossref","is-referenced-by-count":557,"title":["Time-dependent reorganization of brain circuitry underlying long-term memory storage"],"prefix":"10.1038","volume":"400","author":[{"given":"Bruno","family":"Bontempi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Laurent-Demir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude","family":"Destrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Jaffard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF23270_CR1","doi-asserted-by":"publisher","first-page":"3943","DOI":"10.1523\/JNEUROSCI.18-10-03943.1998","volume":"18","author":"JM Reed","year":"1998","unstructured":"Reed, J. M. & Squire, L. R. Retrograde amnesia for facts and events: findings from four new cases. J. Neurosci. 18, 3943\u20133954 (1998).","journal-title":"J. Neurosci."},{"key":"BF23270_CR2","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1037\/0033-295X.99.2.195","volume":"99","author":"LR Squire","year":"1992","unstructured":"Squire, L. R. Memory and the hippocampus: a synthesis from findings with rats, monkeys and humans. Psychol. Rev. 99, 195\u2013231 (1992).","journal-title":"Psychol. Rev."},{"key":"BF23270_CR3","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1126\/science.2218534","volume":"250","author":"SM Zola-Morgan","year":"1990","unstructured":"Zola-Morgan, S. M. & Squire, L. R. The primate hippocampal formation: evidence for a time-limited role in memory storage. Science 250, 288\u2013290 (1990).","journal-title":"Science"},{"key":"BF23270_CR4","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1523\/JNEUROSCI.19-03-01106.1999","volume":"19","author":"SG Anagnostaras","year":"1999","unstructured":"Anagnostaras, S. G., Maren, S. & Fanselow, M. S. Temporally graded retrograde amnesia of contextual fear after hippocampal damage in rats: within-subjects examination. J. Neurosci. 19, 1106\u20131114 (1999).","journal-title":"J. Neurosci."},{"key":"BF23270_CR5","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/S0959-4388(98)80155-4","volume":"8","author":"M Moscovitch","year":"1998","unstructured":"Moscovitch, M. & Nadel, L. Consolidation and the hippocampal complex revisited: in defense of the multiple-trace model. Curr. Opin. Neurobiol. 8, 297\u2013300 (1998).","journal-title":"Curr. Opin. Neurobiol."},{"key":"BF23270_CR6","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/S0959-4388(98)80154-2","volume":"8","author":"BJ Knowlton","year":"1998","unstructured":"Knowlton, B. J. & Fanselow, M. S. The hippocampus, consolidation and on-line memory. Curr. Opin. Neurobiol. 8, 293\u2013296 (1998).","journal-title":"Curr. Opin. Neurobiol."},{"key":"BF23270_CR7","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1162\/jocn.1991.3.2.95","volume":"3","author":"MR Polster","year":"1991","unstructured":"Polster, M. R., Nadel, L. & Schacter, D. L. Cognitive neuroscience analysis of memory: a historical perspective. J. Cogn. Neurosci. 3, 95\u2013116 (1991).","journal-title":"J. Cogn. Neurosci."},{"key":"BF23270_CR8","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/S0896-6273(00)80168-3","volume":"17","author":"Y Dudai","year":"1996","unstructured":"Dudai, Y. Consolidation: fragility on the road to the engram. Neuron 17, 367\u2013370 (1996).","journal-title":"Neuron"},{"key":"BF23270_CR9","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/0959-4388(95)80023-9","volume":"5","author":"LR Squire","year":"1995","unstructured":"Squire, L. R. & Alvarez, P. Retrograde amnesia and memory consolidation: a neurobiological perspective. Curr. Opin. Neurobiol. 5, 169\u2013177 (1995).","journal-title":"Curr. Opin. Neurobiol."},{"key":"BF23270_CR10","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1111\/j.1471-4159.1977.tb10649.x","volume":"28","author":"L Sokoloff","year":"1977","unstructured":"Sokoloff, L.et al. The 14C-deoxyglucose method for measurement of local cerebral glucose utilization: theory, procedure and normal values in the conscious and anesthetized albino rat. J. Neurochem. 28, 897\u2013916 (1977).","journal-title":"J. Neurochem."},{"key":"BF23270_CR11","doi-asserted-by":"publisher","first-page":"2348","DOI":"10.1111\/j.1460-9568.1996.tb01198.x","volume":"8","author":"B Bontempi","year":"1996","unstructured":"Bontempi, B., Jaffard, R. & Destrade, C. Differential temporal evolution of post-training changes in regional brain glucose metabolism induced by repeated spatial discrimination training in mice: visualization of the memory consolidation process? Eur. J. Neurosci. 8, 2348\u20132360 (1996).","journal-title":"Eur. J. Neurosci."},{"key":"BF23270_CR12","doi-asserted-by":"publisher","first-page":"1759","DOI":"10.1523\/JNEUROSCI.13-04-01759.1993","volume":"13","author":"YH Cho","year":"1993","unstructured":"Cho, Y. H., Beracochea, D. & Jaffard, R. Extended temporal gradient for the retrograde and anterograde amnesia produced by ibotenate entorhinal cortex lesions in mice. J. Neurosci. 13, 1759\u20131766 (1993).","journal-title":"J. Neurosci."},{"key":"BF23270_CR13","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1016\/0014-4886(84)90116-X","volume":"83","author":"DM Finch","year":"1984","unstructured":"Finch, D. M., Derian, E. L. & Babb, T. L. Afferent fibers to rat cingulate cortex. Exp. Neurol. 83, 468\u2013485 (1984).","journal-title":"Exp. Neurol."},{"key":"BF23270_CR14","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/0304-3940(89)90535-1","volume":"101","author":"J Sif","year":"1989","unstructured":"Sif, J., Meunier, M., Messier, C., Calas, A. & Destrade, C. Quantitative (14C)2-deoxyglucose study of a functional dissociation between anterior and posterior cingulate cortices in mice. Neurosci. Lett. 101, 223\u2013228 (1989).","journal-title":"Neurosci. Lett."},{"key":"BF23270_CR15","doi-asserted-by":"publisher","first-page":"3753","DOI":"10.1523\/JNEUROSCI.16-11-03753.1996","volume":"16","author":"L Nyberg","year":"1996","unstructured":"Nyberg, L.et al. Network analysis of positron emission tomography regional cerebral blood flow data: ensemble inhibition during episodic memory retrieval. J. Neurosci. 16, 3753\u20133759 (1996).","journal-title":"J. Neurosci."},{"key":"BF23270_CR16","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1037\/0735-7044.100.2.147","volume":"100","author":"TJ Teyler","year":"1986","unstructured":"Teyler, T. J. & DiScenna, P. The hippocampal memory indexing theory. Behav. Neurosci. 100, 147\u2013154 (1986).","journal-title":"Behav. Neurosci."},{"key":"BF23270_CR17","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/0010-0277(89)90005-X","volume":"33","author":"AR Damasio","year":"1989","unstructured":"Damasio, A. R. Time-locked multiregional retroactivation: a systems-level proposal for the neural substrates of recall and recognition. Cognition 33, 25\u201362 (1989).","journal-title":"Cognition"},{"key":"BF23270_CR18","volume-title":"The Hippocampus as a Cognitive Map","author":"J O'Keefe","year":"1978","unstructured":"O'Keefe, J. & Nadel, L. The Hippocampus as a Cognitive Map (Oxford Univ. Press, 1978)."},{"key":"BF23270_CR19","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/S0166-4328(05)80018-X","volume":"44","author":"M Meunier","year":"1991","unstructured":"Meunier, M., Jaffard, R. & Destrade, C. Differential involvement of anterior and posterior cingulate cortices in spatial discrimination learning in a T-maze in mice. Behav. Brain Res. 44, 133\u2013143 (1991).","journal-title":"Behav. Brain Res."},{"key":"BF23270_CR20","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/0165-0173(95)00007-0","volume":"21","author":"HJ Markowitsch","year":"1995","unstructured":"Markowitsch, H. J. Which brain regions are critically involved in the retrieval of old episodic memory. Brain Res. Rev. 21, 117\u2013127 (1995).","journal-title":"Brain Res. Rev."},{"key":"BF23270_CR21","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1038\/7221","volume":"2","author":"RL Buckner","year":"1999","unstructured":"Buckner, R. L., Kelley, W. M. & Petersen, S. E. Frontal cortex contributes to human memory formation. Nature Neurosci. 2, 311\u2013314 (1999).","journal-title":"Nature Neurosci."},{"key":"BF23270_CR22","doi-asserted-by":"publisher","first-page":"4275","DOI":"10.1523\/JNEUROSCI.16-13-04275.1996","volume":"16","author":"GR Fink","year":"1996","unstructured":"Fink, G. R.et al. Cerebral representation of one's own past: neural networks involved in autobiographical memory. J. Neurosci. 16, 4275\u20134282 (1996).","journal-title":"J. Neurosci."},{"key":"BF23270_CR23","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1126\/science.270.5237.769","volume":"270","author":"LG Ungerleider","year":"1995","unstructured":"Ungerleider, L. G. Functional brain imaging studies of cortical mechanisms for memory. Science 270, 769\u2013775 (1995).","journal-title":"Science"},{"key":"BF23270_CR24","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1073\/pnas.93.1.321","volume":"93","author":"DL Schacter","year":"1996","unstructured":"Schacter, D. L., Alpert, N. M., Savage, C. R., Rauch, S. L. & Albert, M. S. Conscious recollection and the human hippocampal formation: evidence from positron emission tomography. Proc. Natl Acad. Sci. USA 93, 321\u2013325 (1996).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BF23270_CR25","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1146\/annurev.psych.49.1.87","volume":"49","author":"JDE Gabrieli","year":"1998","unstructured":"Gabrieli, J. D. E. Cognitive neuroscience of human memory. Annu. Rev. Psychol. 49, 87\u2013115 (1998).","journal-title":"Annu. Rev. Psychol."},{"key":"BF23270_CR26","doi-asserted-by":"publisher","first-page":"14506","DOI":"10.1073\/pnas.95.24.14506","volume":"95","author":"MT Alkire","year":"1998","unstructured":"Alkire, M. T., Haier, R. J., Fallon, J. H. & Cahill, L. Hippocampal, but not amygdala, activity at encoding correlates with long-term, free recall of nonemotional information. Proc. Natl Acad. Sci. USA 95, 14506\u201314510 (1998).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BF23270_CR27","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1046\/j.1365-2869.7.s1.3.x","volume":"7","author":"G Buzsaki","year":"1998","unstructured":"Buzsaki, G. Memory consolidation during sleep: a neuropsychological perspective. J. Sleep Res. 7, 17\u201323 (1998).","journal-title":"J. Sleep Res."},{"key":"BF23270_CR28","volume-title":"Atlas St\u00e9r\u00e9otaxique du Cerveau de la Souris","author":"A Lehman","year":"1974","unstructured":"Lehman, A. Atlas St\u00e9r\u00e9otaxique du Cerveau de la Souris (Editions du CNRS, Paris, 1974)."},{"key":"BF23270_CR29","doi-asserted-by":"publisher","first-page":"1717","DOI":"10.1152\/jn.1994.72.4.1717","volume":"72","author":"AR McIntosh","year":"1994","unstructured":"McIntosh, A. R. & Gonzalez-Lima, F. Network interactions among limbic cortices, basal forebrain and cerebellum differentiate a tone conditioned as a Pavlovian excitor or inhibitor: fluorodeoxyglucose mapping and covariance structural modelling. J. Neurophysiol. 72, 1717\u20131733 (1994).","journal-title":"J. Neurophysiol."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/23270.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/23270","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/23270.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T19:22:13Z","timestamp":1638386533000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/23270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,8]]},"references-count":29,"journal-issue":{"issue":"6745","published-print":{"date-parts":[[1999,8]]}},"alternative-id":["BF23270"],"URL":"https:\/\/doi.org\/10.1038\/23270","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,8]]}}}