{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T06:43:34Z","timestamp":1791009814016,"version":"4.1.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"5442","license":[{"start":{"date-parts":[[1974,2,1]],"date-time":"1974-02-01T00:00:00Z","timestamp":128908800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1974,2]]},"DOI":"10.1038\/247546a0","type":"journal-article","created":{"date-parts":[[2005,8,3]],"date-time":"2005-08-03T19:56:23Z","timestamp":1123098983000},"page":"546-549","source":"Crossref","is-referenced-by-count":44,"title":["Acid Protease Activity in Plasmodium falciparum and P. knowlesi and Ghosts of Their Respective Host Red Cells"],"prefix":"10.1038","volume":"247","author":[{"given":"MICHAEL R.","family":"LEVY","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. A.","family":"SIDDIQUI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. C.","family":"CHOU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF247546a0_CR1","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/B978-1-4832-3139-6.50010-0","volume-title":"Biochemistry and Physiology of Protozoa","author":"RW McKee","year":"1951","unstructured":"McKee, R. W., in Biochemistry and Physiology of Protozoa (edit. by Lwoff, A.), 251 (Academic Press, New York, 1951)."},{"key":"BF247546a0_CR2","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1042\/bj0630274","volume":"63","author":"JD Fulton","year":"1956","unstructured":"Fulton, J. D., and Grant, P. T., Biochem. J., 63, 274 (1956).","journal-title":"Biochem. J."},{"key":"BF247546a0_CR3","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.3181\/00379727-131-34073","volume":"131","author":"H Polet","year":"1969","unstructured":"Polet, H., Brown, N. D., and Angel, D. R., Proc. Soc. exp. Biol. Med., 131, 1215 (1969).","journal-title":"Proc. Soc. exp. Biol. Med."},{"key":"BF247546a0_CR4","doi-asserted-by":"publisher","first-page":"800","DOI":"10.4269\/ajtmh.1968.17.800","volume":"17","author":"RJ Cenedella","year":"1968","unstructured":"Cenedella, R. J., Rosen, H., Angel, C. R., and Saxes, L. H., Am. J. trop. Med. Hyg., 17, 800 (1968).","journal-title":"Am. J. trop. Med. Hyg."},{"key":"BF247546a0_CR5","first-page":"929","volume":"134","author":"WA Siddiqui","year":"1969","unstructured":"Siddiqui, W. A., and Schnell, J. V., Milit. Med., 134, 929 (1969).","journal-title":"Milit. Med."},{"key":"BF247546a0_CR6","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0021-9258(18)43054-2","volume":"164","author":"JW Moulder","year":"1946","unstructured":"Moulder, J. W., and Evans, E. A., Jr., J. biol. Chem., 164, 145 (1946).","journal-title":"J. biol. Chem."},{"key":"BF247546a0_CR7","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/0014-4894(61)90041-8","volume":"11","author":"L Cook","year":"1961","unstructured":"Cook, L., Grant, P. T., and Kermack, W. O., Expl. Parasit., 11, 372 (1961).","journal-title":"Expl. Parasit."},{"key":"BF247546a0_CR8","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.2307\/3278644","volume":"59","author":"MR Levy","year":"1973","unstructured":"Levy, M. R., and Chou, S. C., J. Parasit., 59, 1064 (1973).","journal-title":"J. Parasit."},{"key":"BF247546a0_CR9","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1093\/milmed\/134.9.866","volume":"134","author":"RT Cook","year":"1969","unstructured":"Cook, R. T., Aikawa, M., Rock, R. C., Little, W., and Spring, H., Milit. Med., 134, 866 (1969).","journal-title":"Milit. Med."},{"key":"BF247546a0_CR10","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1093\/milmed\/134.9.825","volume":"134","author":"RL Ladda","year":"1969","unstructured":"Ladda, R. L., Milit. Med., 134, 825 (1969).","journal-title":"Milit. Med."},{"key":"BF247546a0_CR11","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0021-9258(18)38435-7","volume":"206","author":"W Morrison","year":"1953","unstructured":"Morrison, W., and Neurath, H., J. biol. Chem., 206, 39 (1953).","journal-title":"J. biol. Chem."},{"key":"BF247546a0_CR12","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1038\/newbio233260a0","volume":"233","author":"WJ Martin","year":"1971","unstructured":"Martin, W. J., Finerty, J., and Rosenthal, A., Nature new Biol., 233, 260 (1971).","journal-title":"Nature new Biol."},{"key":"BF247546a0_CR13","doi-asserted-by":"publisher","first-page":"586","DOI":"10.4269\/ajtmh.1970.19.586","volume":"19","author":"WA Siddiqui","year":"1970","unstructured":"Siddiqui, W. A., Schnell, J. V., and Geiman, Q. M., Am. J. trop. Med. Hyg., 19, 586 (1970).","journal-title":"Am. J. trop. Med. Hyg."},{"key":"BF247546a0_CR14","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1016\/0006-3002(60)91281-6","volume":"38","author":"A Torriani","year":"1960","unstructured":"Torriani, A., Biochim. biophys. Acta, 38, 460 (1960).","journal-title":"Biochim. biophys. Acta"},{"key":"BF247546a0_CR15","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"OH Lowry","year":"1951","unstructured":"Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., J. biol. Chem., 193, 265 (1951).","journal-title":"J. biol. Chem."},{"key":"BF247546a0_CR16","doi-asserted-by":"publisher","first-page":"259","DOI":"10.7164\/antibiotics.23.259","volume":"23","author":"H Umezawa","year":"1970","unstructured":"Umezawa, H., Aoyagi, T., Morishima, H., Matsuzaki, M., Hamada, M., and Takeuchi, T., J. Antibiot., 23, 259 (1970).","journal-title":"J. Antibiot."},{"key":"BF247546a0_CR17","doi-asserted-by":"publisher","first-page":"425","DOI":"10.7164\/antibiotics.23.425","volume":"23","author":"H Umezawa","year":"1970","unstructured":"Umezawa, H., Aoyagi, T., Morishima, H., Kunimoto, S., Matsuzaki, M., Hanada, M., and Takeuchi, T., J. Antibiot., 23, 425 (1970).","journal-title":"J. Antibiot."},{"key":"BF247546a0_CR18","doi-asserted-by":"publisher","first-page":"263","DOI":"10.7164\/antibiotics.25.263","volume":"25","author":"H Suda","year":"1972","unstructured":"Suda, H., Aoyagi, T., Hamada, M., Takeuchi, T., and Umezawa, H., J. Antibiot., 25, 263 (1972).","journal-title":"J. Antibiot."},{"key":"BF247546a0_CR19","doi-asserted-by":"publisher","first-page":"283","DOI":"10.7164\/antibiotics.22.283","volume":"22","author":"T Aoyagi","year":"1969","unstructured":"Aoyagi, T., Takeuchi, T., Matsuzaki, A., Kawamura, K., Konda, S., Hamada, M., Maeda, K., and Umezawa, H., J. Antibiot., 22, 283 (1969).","journal-title":"J. Antibiot."},{"key":"BF247546a0_CR20","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/0005-2744(72)90121-0","volume":"289","author":"T Koto","year":"1972","unstructured":"Koto, T., Kojima, K., and Murachi, T., Biochim. biophys. Acta, 289, 187 (1972).","journal-title":"Biochim. biophys. Acta"},{"key":"BF247546a0_CR21","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1042\/bj1270439","volume":"127","author":"AJ Barrett","year":"1972","unstructured":"Barrett, A. J., and Dingle, J. T., Biochem. J., 127, 439 (1972).","journal-title":"Biochem. J."},{"key":"BF247546a0_CR22","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1042\/bj1270443","volume":"127","author":"JT Dingle","year":"1972","unstructured":"Dingle, J. T., Barrett, A. J., and Poole, A. R., Biochem. J., 127, 443 (1972).","journal-title":"Biochem. J."},{"key":"BF247546a0_CR23","doi-asserted-by":"crossref","unstructured":"Davies, M., Lloyd, J. B., and Beck, F., Biochem. J., 121 (1971).","DOI":"10.1042\/bj1210021"},{"key":"BF247546a0_CR24","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1080\/00034983.1972.11686812","volume":"66","author":"JV Scorza","year":"1972","unstructured":"Scorza, J. V., De Scorza, C., and Monteiro, M. C. C., Ann. trop. Med. Parasit., 66, 167 (1972).","journal-title":"Ann. trop. Med. Parasit."},{"key":"BF247546a0_CR25","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1080\/00034983.1973.11686889","volume":"67","author":"RE Howells","year":"1973","unstructured":"Howells, R. E., and Maxwell, L., Ann. trop. Med. Parasit., 67, 285 (1973).","journal-title":"Ann. trop. Med. Parasit."},{"key":"BF247546a0_CR26","first-page":"153","volume":"72","author":"A Voller","year":"1969","unstructured":"Voller, A., Richards, W. H., Hawkey, C. M., and Ridley, D. S., J. trop. Med. Hyg., 72, 153 (1969).","journal-title":"J. trop. Med. Hyg."},{"key":"BF247546a0_CR27","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1093\/milmed\/134.9.1068","volume":"134","author":"JV Schnell","year":"1969","unstructured":"Schnell, J. V., Siddiqui, W. A., and Geiman, Q. M., Milit. Med., 134, 1068 (1969).","journal-title":"Milit. Med."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/247546a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/247546a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/247546a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T23:47:57Z","timestamp":1638402477000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/247546a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,2]]},"references-count":27,"journal-issue":{"issue":"5442","published-print":{"date-parts":[[1974,2]]}},"alternative-id":["BF247546a0"],"URL":"https:\/\/doi.org\/10.1038\/247546a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1974,2]]}}}