{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T10:54:48Z","timestamp":1758279288771},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"5482","license":[{"start":{"date-parts":[[1974,11,1]],"date-time":"1974-11-01T00:00:00Z","timestamp":152496000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1974,11]]},"DOI":"10.1038\/252354a0","type":"journal-article","created":{"date-parts":[[2005,8,3]],"date-time":"2005-08-03T19:00:45Z","timestamp":1123095645000},"page":"354-359","source":"Crossref","is-referenced-by-count":89,"title":["Sequence analysis of immunoglobulin light chain messenger RNA"],"prefix":"10.1038","volume":"252","author":[{"given":"C.","family":"Milstein","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. G.","family":"Brownlee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. M.","family":"Cartwright","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"Jarvis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. J.","family":"Proudfoot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF252354a0_CR1","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1038\/newbio244236a0","volume":"244","author":"GG Brownlee","year":"1973","unstructured":"Brownlee, G. G., Cartwright, E. M., Cowan, N. J., Jarvis, J. M., and Milstein, C., Nature new Biol, 244, 236\u2013240 (1973).","journal-title":"Nature new Biol"},{"key":"BF252354a0_CR2","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/0014-5793(74)80108-0","volume":"38","author":"NJ Proudfoot","year":"1974","unstructured":"Proudfoot, N. J., and Brownlee, G. G., FEBS Lett., 38, 179\u2013183 (1974).","journal-title":"FEBS Lett."},{"key":"BF252354a0_CR3","doi-asserted-by":"publisher","first-page":"2300","DOI":"10.1073\/pnas.71.6.2300","volume":"71","author":"CA Marotta","year":"1974","unstructured":"Marotta, C. A., Forget, B. G., Weissman, S. M., Verma, I. M., McCaffery, R. P., and Baltimore, D., Proc. natn. Acad. Sci. U.S.A., 71, 2300\u20132304 (1974).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF252354a0_CR4","volume-title":"Virus Research","author":"W Salser","year":"1973","unstructured":"Salser, W., Poon, R., Whitcome, P., and Fry, K., in Virus Research, (edit. by Fox, C. F., and Robinson, W. S., Academic Press, New York, 1973)."},{"key":"BF252354a0_CR5","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1038\/252359a0","volume":"252","author":"NJ Proudfoot","year":"1974","unstructured":"Proudfoot, N. J., and Brownlee, G. G. Nature, 252, 359 (1974).","journal-title":"Nature"},{"key":"BF252354a0_CR6","first-page":"199","volume-title":"Defence and Recognition, MTP International Review of Science, Biochemistry","author":"C Milstein","year":"1973","unstructured":"Milstein, C., and Munro, A. J., Defence and Recognition, MTP International Review of Science, Biochemistry (edit. by Porter, R. R.), 10, 199\u2013228 (1973)."},{"key":"BF252354a0_CR7","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1101\/SQB.1967.032.01.034","volume":"32","author":"ES Lennox","year":"1967","unstructured":"Lennox, E. S., Knopf, P. M., Munro, A. J., and Parkhouse, R. M. E., Cold Spring Harb. Symp. quant. Biol., 32, 249\u2013254 (1967).","journal-title":"Cold Spring Harb. Symp. quant. Biol."},{"key":"BF252354a0_CR8","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1038\/newbio230172a0","volume":"230","author":"J Stavnezer","year":"1971","unstructured":"Stavnezer, J., and Huang, R. C. C., Nature new Biol., 230, 172\u2013176 (1971).","journal-title":"Nature new Biol."},{"key":"BF252354a0_CR9","first-page":"245","volume-title":"Cellular Selection and Regulation in the Immune Response","author":"C Milstein","year":"1974","unstructured":"Milstein, C., Secher, D. S., Cowan, N. J., Harrison, T. M., Cotton, R. G. H., and Brownlee, G. G., Cellular Selection and Regulation in the Immune Response (edit. by Edelman, G. M.), 245\u2013264, (Raven Press, New York, 1974)."},{"key":"BF252354a0_CR10","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1111\/j.1432-1033.1974.tb03734.x","volume":"47","author":"TM Harrison","year":"1974","unstructured":"Harrison, T. M., Brownlee, G. G., and Milstein, C., Europ. J. Biochem., 47, 621\u2013627 (1974).","journal-title":"Europ. J. Biochem."},{"key":"BF252354a0_CR11","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1073\/pnas.70.2.451","volume":"70","author":"B Mach","year":"1973","unstructured":"Mach, B., Faust, C., and Vassalli, P., Proc. natn. Acad. Sci. U.S.A., 70, 451\u2013455 (1973).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF252354a0_CR12","doi-asserted-by":"publisher","first-page":"1967","DOI":"10.1073\/pnas.69.7.1967","volume":"69","author":"D Swan","year":"1972","unstructured":"Swan, D., Aviv, H., and Leder, P., Proc. natn. Acad. Sci. U.S.A., 69, 1967\u20131971 (1972).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF252354a0_CR13","doi-asserted-by":"publisher","first-page":"2256","DOI":"10.1073\/pnas.70.8.2256","volume":"70","author":"I Schechter","year":"1973","unstructured":"Schechter, I., Proc. natn. Acad. Sci. U.S.A., 70, 2256\u20132260 (1973).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF252354a0_CR14","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1042\/bj1260837","volume":"126","author":"J Svasti","year":"1972","unstructured":"Svasti, J., and Milstein, C., Biochem. J., 126, 837\u2013850 (1972).","journal-title":"Biochem. J."},{"key":"BF252354a0_CR15","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1038\/newbio241034a0","volume":"241","author":"EB Ziff","year":"1973","unstructured":"Ziff, E. B., Sedat, J. W., and Galibert, F., Nature new Biol., 241, 34\u201337 (1973).","journal-title":"Nature new Biol."},{"key":"BF252354a0_CR16","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1073\/pnas.70.4.1209","volume":"70","author":"F Sanger","year":"1973","unstructured":"Sanger, F., Donelson, J. E., Coulson, A. R., K\u00f6ssel, H., and Fischer, D., Proc. natn. Acad. Sci. U.S.A., 70, 1209\u20131213 (1973).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF252354a0_CR17","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1016\/0014-5793(74)80756-8","volume":"42","author":"TH Rabbitts","year":"1974","unstructured":"Rabbitts, T. H., FEBS Lett., 42, 323\u2013326 (1974).","journal-title":"FEBS Lett."},{"key":"BF252354a0_CR18","first-page":"3","volume-title":"Part I of Laboratory Techniques in Biochemistry and Molecular Biology","author":"GG Brownlee","year":"1972","unstructured":"Brownlee, G. G., Part I of Laboratory Techniques in Biochemistry and Molecular Biology (edit. by Work, T. S. and Work, E.), 3 (North-Holland Publishing Co., Amsterdam and London, 1972)."},{"key":"BF252354a0_CR19","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1038\/newbio239117a0","volume":"239","author":"C Milstein","year":"1972","unstructured":"Milstein, C., Brownlee, G. G., Harrison, T. M., and Mathews, M. B., Nature new Biol., 239, 117\u2013120 (1972).","journal-title":"Nature new Biol."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/252354a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/252354a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/252354a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T07:24:27Z","timestamp":1684221867000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/252354a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,11]]},"references-count":19,"journal-issue":{"issue":"5482","published-print":{"date-parts":[[1974,11]]}},"alternative-id":["BF252354a0"],"URL":"https:\/\/doi.org\/10.1038\/252354a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1974,11]]}}}