{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T20:52:20Z","timestamp":1776804740361,"version":"3.51.2"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"5515","license":[{"start":{"date-parts":[[1975,7,1]],"date-time":"1975-07-01T00:00:00Z","timestamp":173404800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1975,7]]},"DOI":"10.1038\/256273a0","type":"journal-article","created":{"date-parts":[[2005,8,3]],"date-time":"2005-08-03T18:10:30Z","timestamp":1123092630000},"page":"273-278","source":"Crossref","is-referenced-by-count":129,"title":["A-Protein gene of bacteriophage MS2"],"prefix":"10.1038","volume":"256","author":[{"given":"W.","family":"Fiers","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Contreras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Duerinck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Haegmean","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Merregaert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. Min","family":"Jou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Raeymakers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Volckaert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ysebaert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Van de Kerckhove","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Nolf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Van Montagu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF256273a0_CR1","first-page":"271","volume-title":"Handbook of Genetics","author":"W Fiers","year":"1974","unstructured":"Fiers, W., in Handbook of Genetics (edit. by King, R. C.), 1, 271\u2013294 (1974)."},{"key":"BF256273a0_CR2","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1146\/annurev.bi.42.070173.001511","volume":"42","author":"C Weissmann","year":"1973","unstructured":"Weissmann, C., Billeter, M. A., Goodman, H. M., Hindley, J., and Weber, H., A. Rev. Biochem., 42, 303\u2013328 (1973).","journal-title":"A. Rev. Biochem."},{"key":"BF256273a0_CR3","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1038\/226230a0","volume":"226","author":"PGN Jeppesen","year":"1970","unstructured":"Jeppesen, P. G. N., Argetsinger-Steitz, J., Gesteland, R. F., and Spahr, P. F., Nature, 226, 230\u2013237 (1970).","journal-title":"Nature"},{"key":"BF256273a0_CR4","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1016\/0022-2836(68)90329-X","volume":"33","author":"J Argetsinger-Steitz","year":"1968","unstructured":"Argetsinger-Steitz, J., J. molec. Biol., 33, 937\u2013945 (1968).","journal-title":"J. molec. Biol."},{"key":"BF256273a0_CR5","doi-asserted-by":"publisher","first-page":"1844","DOI":"10.1073\/pnas.56.6.1844","volume":"56","author":"D Nathans","year":"1966","unstructured":"Nathans, D., Oeschger, M. P., Eggen, K., and Shimura, Y., Proc. natn. Acad. Sci. U.S.A., 56, 1844\u20131851 (1966).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF256273a0_CR6","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1016\/0022-2836(68)90328-8","volume":"33","author":"J Argetsinger-Steitz","year":"1968","unstructured":"Argetsinger-Steitz, J., J. molec. Biol., 33, 923\u2013936 (1968).","journal-title":"J. molec. Biol."},{"key":"BF256273a0_CR7","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/0022-2836(72)90349-X","volume":"71","author":"E Remaut","year":"1972","unstructured":"Remaut, E., and Fiers, W., J. molec. Biol., 71, 243\u2013261 (1972).","journal-title":"J. molec. Biol."},{"key":"BF256273a0_CR8","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/0042-6822(65)90154-6","volume":"27","author":"HF Lodish","year":"1965","unstructured":"Lodish, H. F., Horiuchi, K., and Zinder, N. D., Virology, 27, 139\u2013155 (1965).","journal-title":"Virology"},{"key":"BF256273a0_CR9","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/0022-2836(66)90016-7","volume":"21","author":"JE Argetsinger","year":"1966","unstructured":"Argetsinger, J. E., and Gussin, G. N., J. molec. Biol., 21, 421\u2013434 (1966).","journal-title":"J. molec. Biol."},{"key":"BF256273a0_CR10","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/S0006-291X(67)80051-2","volume":"27","author":"M Heisenberg","year":"1967","unstructured":"Heisenberg, M., Biochem. biophys. Res. Commun., 27, 131\u2013137 (1967).","journal-title":"Biochem. biophys. Res. Commun."},{"key":"BF256273a0_CR11","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/0014-5793(72)80684-7","volume":"28","author":"E Verbraeken","year":"1972","unstructured":"Verbraeken, E., and Fiers, W., FEBS Lett., 28, 89\u201392 (1972).","journal-title":"FEBS Lett."},{"key":"BF256273a0_CR12","first-page":"209","volume":"234","author":"M Kozak","year":"1971","unstructured":"Kozak, M., and Nathans, D., Nature, 234, 209\u2013211 (1971).","journal-title":"Nature"},{"issue":"3","key":"BF256273a0_CR13","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1016\/0042-6822(72)90552-1","volume":"47","author":"P.M. Krahn","year":"1972","unstructured":"Krahn, P. M., O'Callaghan, R. J., and Paranchych, W., Virology, 47, 628\u2013627 (1972).","journal-title":"Virology"},{"key":"BF256273a0_CR14","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1126\/science.134.3495.2007.a","volume":"134","author":"JE Davis","year":"1961","unstructured":"Davis, J. E., Strauss, J. H., and Sinsheimer, R. L., Science, 134, 1427 (1961).","journal-title":"Science"},{"key":"BF256273a0_CR15","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1038\/224957a0","volume":"224","author":"J Argetsinger-Steitz","year":"1969","unstructured":"Argetsinger-Steitz, J., Nature, 224, 957\u2013964 (1969).","journal-title":"Nature"},{"key":"BF256273a0_CR16","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1073\/pnas.68.3.585","volume":"68","author":"R De Wachter","year":"1971","unstructured":"De Wachter, R., Vandenberghe, A., Merregaert, J., Contreras, R., and Fiers, W., Proc. natn. Acad. Sci. U.S.A., 68, 585\u2013589 (1971).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF256273a0_CR17","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1111\/j.1432-1033.1971.tb01558.x","volume":"22","author":"R De Wachter","year":"1971","unstructured":"De Wachter, R., Merregaert, J., Vandenberghe, A., Contreras, R., and Fiers, W., Eur. J. Biochem., 22, 400\u2013414 (1971).","journal-title":"Eur. J. Biochem."},{"key":"BF256273a0_CR18","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/0014-5793(73)80584-8","volume":"35","author":"G Volckaert","year":"1973","unstructured":"Volckaert, G., and Fiers, W., FEBS Lett., 35, 91\u201396 (1973).","journal-title":"FEBS Lett."},{"key":"BF256273a0_CR19","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1038\/newbio241099a0","volume":"241","author":"R Contreras","year":"1973","unstructured":"Contreras, R., Ysebaert, M., Min Jou, W., and Fiers, W., Nature new Biol., 241, 99\u2013101 (1973).","journal-title":"Nature new Biol."},{"key":"BF256273a0_CR20","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1042\/bj1310593","volume":"131","author":"UFE Rensing","year":"1973","unstructured":"Rensing, U. F. E., Biochem. J., 131, 593\u2013604 (1973).","journal-title":"Biochem. J."},{"key":"BF256273a0_CR21","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1042\/bj1310605","volume":"131","author":"UFE Rensing","year":"1973","unstructured":"Rensing, U. F. E., and Coulson, A., Biochem. J., 131, 605\u2013610 (1973).","journal-title":"Biochem. J."},{"key":"BF256273a0_CR22","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1111\/j.1432-1033.1973.tb02648.x","volume":"33","author":"UFE Rensing","year":"1973","unstructured":"Rensing, U. F. E., and Schoenmakers, J. G. G., Eur. J. Biochem., 33, 8\u201318 (1973).","journal-title":"Eur. J. Biochem."},{"key":"BF256273a0_CR23","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1111\/j.1432-1033.1974.tb03284.x","volume":"41","author":"UFE Rensing","year":"1974","unstructured":"Rensing, U. F. E., Coulson, A., and Schoenmakers, J. G. G., Eur. J. Biochem., 41, 431\u2013438 (1974).","journal-title":"Eur. J. Biochem."},{"key":"BF256273a0_CR24","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1111\/j.1432-1033.1973.tb02893.x","volume":"36","author":"G Haegeman","year":"1973","unstructured":"Haegeman, G., and Fiers, W., Eur. J. Biochem., 36, 135\u2013143 (1973).","journal-title":"Eur. J. Biochem."},{"key":"BF256273a0_CR25","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1038\/newbio241102a0","volume":"241","author":"J Vandekerckhove","year":"1973","unstructured":"Vandekerckhove, J., Nolf, F., and Van Montagu, M., Nature new Biol., 241, 102 (1973).","journal-title":"Nature new Biol."},{"key":"BF256273a0_CR26","first-page":"194","volume":"76","author":"W Min Jou","year":"1968","unstructured":"Min Jou, W., Hindley, J., and Fiers, W., Archs intern. Physiol. Biochim., 76, 194\u2013195 (1968).","journal-title":"Archs intern. Physiol. Biochim."},{"key":"BF256273a0_CR27","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1038\/2231009a0","volume":"223","author":"JM Adams","year":"1969","unstructured":"Adams, J. M., Jeppesen, P. G. N., Sanger, F., and Barrell, B. G., Nature, 223, 1009\u20131014 (1969).","journal-title":"Nature"},{"key":"BF256273a0_CR28","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/0003-2697(67)90018-8","volume":"18","author":"R De Wachter","year":"1967","unstructured":"De Wachter, R., and Fiers, W., Analyt. Biochem., 18, 351\u2013374 (1967).","journal-title":"Analyt. Biochem."},{"key":"BF256273a0_CR29","first-page":"361","volume-title":"Methods in Enzymology","author":"F Sanger","year":"1967","unstructured":"Sanger, F., and Brownlee, G., Methods in Enzymology, 12 A (edit. by Colowick, S. P., and Kaplan, N. O.), 361\u2013381 (Academic, New York and London, 1967)."},{"key":"BF256273a0_CR30","unstructured":"Contreras, R., and Fiers, W., Analyt. Biochem. (in the press)."},{"key":"BF256273a0_CR31","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/0022-2836(69)90494-X","volume":"42","author":"W Min Jou","year":"1969","unstructured":"Min Jou, W., Fiers, W., Goodman, H., and Spahr, P., J. molec. Biol., 42, 143\u2013146 (1969).","journal-title":"J. molec. Biol."},{"key":"BF256273a0_CR32","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/0014-5793(71)80370-8","volume":"16","author":"R Contreras","year":"1971","unstructured":"Contreras, R., and Fiers, W., FEBS Lett., 16, 281\u2013283 (1971).","journal-title":"FEBS Lett."},{"key":"BF256273a0_CR33","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1038\/newbio246040a0","volume":"246","author":"I Tinoco","year":"1973","unstructured":"Tinoco, I., Borer, P. N., Dengler, B., Levine, M. D., Uhlenbeck, O. C., Crothers, D. M., and Gralla, J., Nature new Biol., 246, 40\u201341 (1973).","journal-title":"Nature new Biol."},{"key":"BF256273a0_CR34","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1038\/250546a0","volume":"250","author":"JD Robertus","year":"1974","unstructured":"Robertus, J. D., Ladner, J. E., Finch, J. T., Rhodes, D., Brown, R. S., Clark, B. F. C., and Klug, A., Nature, 250, 546\u2013551 (1974).","journal-title":"Nature"},{"key":"BF256273a0_CR35","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1111\/j.1432-1033.1970.tb01134.x","volume":"17","author":"M Osborn","year":"1970","unstructured":"Osborn, M., Weiner, A. M., and Weber, K., Eur. J. Biochem., 17, 63\u201367 (1970).","journal-title":"Eur. J. Biochem."},{"key":"BF256273a0_CR36","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1042\/bj1100652","volume":"110","author":"C Milstein","year":"1968","unstructured":"Milstein, C., Biochem. J., 110, 652\u2013654 (1968).","journal-title":"Biochem. J."},{"key":"BF256273a0_CR37","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/0022-2836(70)90023-9","volume":"52","author":"CJ Bruton","year":"1970","unstructured":"Bruton, C. J., and Hartley, B. S., J. molec. Biol., 52, 165\u2013173 (1970).","journal-title":"J. molec. Biol."},{"key":"BF256273a0_CR38","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1111\/j.1432-1033.1974.tb03483.x","volume":"44","author":"J Vandekerckhove","year":"1974","unstructured":"Vandekerckhove, J., and Van Montagu, M., Eur. J. Biochem., 44, 279\u2013288 (1974).","journal-title":"Eur. J. Biochem."},{"key":"BF256273a0_CR39","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1038\/249647b0","volume":"249","author":"N Maizels","year":"1974","unstructured":"Maizels, N., Nature, 249, 647\u2013649 (1974).","journal-title":"Nature"},{"key":"BF256273a0_CR40","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1073\/pnas.71.3.667","volume":"71","author":"JG Files","year":"1974","unstructured":"Files, J. G., Weber, K., and Miller, J. H., Proc. natn. Acad. Sci. U.S.A., 71, 667\u2013670 (1974).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF256273a0_CR41","doi-asserted-by":"publisher","first-page":"4940","DOI":"10.1073\/pnas.71.12.4940","volume":"71","author":"RE Musso","year":"1974","unstructured":"Musso, R. E., De Crombrugghe, B., Pastan, I., Sklar, J., Yot, P., and Weissman, S., Proc. natn. Acad. Sci. U.S.A., 71, 4940\u20134944 (1974).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF256273a0_CR42","doi-asserted-by":"crossref","first-page":"3242","DOI":"10.1016\/S0021-9258(19)45237-X","volume":"247","author":"AM Weiner","year":"1972","unstructured":"Weiner, A. M., Platt, J., and Weber, K., J. biol. Chem., 247, 3242\u20133251 (1972).","journal-title":"J. biol. Chem."},{"key":"BF256273a0_CR43","doi-asserted-by":"publisher","first-page":"2605","DOI":"10.1073\/pnas.70.9.2605","volume":"70","author":"J Argetsinger-Steitz","year":"1973","unstructured":"Argetsinger-Steitz, J., Proc. natn. Acad. Sci. U.S.A., 70, 2605\u20132609 (1973).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF256273a0_CR44","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1073\/pnas.67.2.710","volume":"67","author":"HD Robertson","year":"1970","unstructured":"Robertson, H. D., and Lodish, H. F., Proc. natn. Acad. Sci. U.S.A., 67, 710\u2013716 (1970).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF256273a0_CR45","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1128\/br.36.1.109-134.1972","volume":"36","author":"M Kozak","year":"1972","unstructured":"Kozak, M., and Nathans, D., Bact. Rev., 36, 109\u2013134 (1972).","journal-title":"Bact. Rev."},{"key":"BF256273a0_CR46","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1101\/SQB.1969.034.01.079","volume":"34","author":"W Fiers","year":"1969","unstructured":"Fiers, W., et al., Cold Spring Harb. Symp. quant. Biol., 34, 697\u2013706 (1969).","journal-title":"Cold Spring Harb. Symp. quant. Biol."},{"key":"BF256273a0_CR47","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1007\/BF00271649","volume":"117","author":"E Vandamme","year":"1972","unstructured":"Vandamme, E., Remaut, E., Van Montagu, M., and Fiers, W., Molec. gen. Genet., 117, 219\u2013228 (1972).","journal-title":"Molec. gen. Genet."},{"key":"BF256273a0_CR48","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1038\/237082a0","volume":"237","author":"W Min Jou","year":"1972","unstructured":"Min Jou, W., Haegeman, G., Ysebaert, M., and Fiers, W., Nature, 237, 82\u201388 (1972).","journal-title":"Nature"}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/256273a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/256273a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/256273a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T00:11:07Z","timestamp":1684282267000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/256273a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,7]]},"references-count":48,"journal-issue":{"issue":"5515","published-print":{"date-parts":[[1975,7]]}},"alternative-id":["BF256273a0"],"URL":"https:\/\/doi.org\/10.1038\/256273a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1975,7]]}}}