{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T05:51:50Z","timestamp":1760853110600},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"5611","license":[{"start":{"date-parts":[[1977,6,1]],"date-time":"1977-06-01T00:00:00Z","timestamp":233971200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1977,6]]},"DOI":"10.1038\/267544a0","type":"journal-article","created":{"date-parts":[[2005,8,3]],"date-time":"2005-08-03T06:05:38Z","timestamp":1123049138000},"page":"544-546","source":"Crossref","is-referenced-by-count":109,"title":["Primary structure of porcine relaxin: homology with insulin and related growth factors"],"prefix":"10.1038","volume":"267","author":[{"given":"ROBERT","family":"JAMES","sequence":"first","affiliation":[]},{"given":"HUGH","family":"NIALL","sequence":"additional","affiliation":[]},{"given":"SIMON","family":"KWOK","sequence":"additional","affiliation":[]},{"given":"GILLIAN","family":"BRYANT-GREENWOOD","sequence":"additional","affiliation":[]}],"member":"297","reference":[{"key":"BF267544a0_CR1","doi-asserted-by":"publisher","first-page":"661","DOI":"10.3181\/00379727-23-3107","volume":"23","author":"FL Hisaw","year":"1926","unstructured":"Hisaw, F. L. Proc. Soc. exp. Biol. Med. 23, 661\u2013663 (1926).","journal-title":"Proc. Soc. exp. Biol. Med."},{"key":"BF267544a0_CR2","doi-asserted-by":"publisher","first-page":"3340","DOI":"10.1021\/ja01371a051","volume":"52","author":"HL Fevold","year":"1930","unstructured":"Fevold, H. L., Hisaw, F. L. & Meyer, R. K. J. Am. Chem. Soc. 52, 3340\u20133348 (1930).","journal-title":"J. Am. Chem. Soc."},{"key":"BF267544a0_CR3","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/S0083-6729(08)60670-6","volume":"8","author":"FL Hisaw","year":"1950","unstructured":"Hisaw, F. L. & Zarrow, M. X. Vit. Horm. 8, 151\u2013155 (1950).","journal-title":"Vit. Horm."},{"key":"BF267544a0_CR4","doi-asserted-by":"publisher","first-page":"272","DOI":"10.3181\/00379727-152-39377","volume":"152","author":"EM O'Byrne","year":"1976","unstructured":"O'Byrne, E. M. & Steinetz, B. G. Proc. Soc. exp. Biol. Med. 152, 272\u2013276 (1976).","journal-title":"Proc. Soc. exp. Biol. Med."},{"key":"BF267544a0_CR5","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1126\/science.982052","volume":"194","author":"G Weiss","year":"1976","unstructured":"Weiss, G., O'Byrne, E. M. & Steinetz, B. G. Science 194, 948\u2013949 (1976).","journal-title":"Science"},{"key":"BF267544a0_CR6","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/S0003-9861(74)80025-1","volume":"160","author":"CD Sherwood","year":"1974","unstructured":"Sherwood, C. D. & O'Byrne, E. M. Archs Biochem. Biophys. 160, 185\u2013196 (1974).","journal-title":"Archs Biochem. Biophys."},{"key":"BF267544a0_CR7","first-page":"481","volume":"2","author":"BG Steinetz","year":"1969","unstructured":"Steinetz, B. G., Beach, V. L. & Kroc, R. L. Meth. Horm. Res. 2A, 481\u2013513 (1969).","journal-title":"Meth. Horm. Res."},{"key":"BF267544a0_CR8","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/S0021-9258(18)81308-4","volume":"238","author":"AM Crestfield","year":"1963","unstructured":"Crestfield, A. M., Moore, S. & Stein, W. H. J. biol. Chem. 238, 622\u2013627 (1963).","journal-title":"J. biol. Chem."},{"key":"BF267544a0_CR9","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/0006-291X(76)91059-7","volume":"70","author":"C Schwabe","year":"1976","unstructured":"Schwabe, C., McDonald, J. K. & Steinetz, B. G. Biochem. biophys. Res. Commun. 70, 397\u2013405 (1976).","journal-title":"Biochem. biophys. Res. Commun."},{"key":"BF267544a0_CR10","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1073\/pnas.64.2.771","volume":"64","author":"HD Niall","year":"1969","unstructured":"Niall, H. D., Keutmann, H. T., Copp, D. H. & Potts, J. T. Proc. natn. Acad. Sci. U.S.A. 64, 771\u2013778 (1969).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF267544a0_CR11","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/S0076-6879(72)25020-0","volume":"25","author":"RF Doolittle","year":"1972","unstructured":"Doolittle, R. F. Meth. Enzym. 25, 231\u2013244 (1972).","journal-title":"Meth. Enzym."},{"key":"BF267544a0_CR12","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/S0065-3233(08)60143-6","volume":"26","author":"T Blundell","year":"1972","unstructured":"Blundell, T., Dodson, G., Hodgkin, D. & Mercola, D. Adv. Protein Chem. 26, 279\u2013402 (1972).","journal-title":"Adv. Protein Chem."},{"key":"BF267544a0_CR13","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1038\/257197a0","volume":"257","author":"TL Blundell","year":"1975","unstructured":"Blundell, T. L. Nature 257, 197\u2013203 (1975).","journal-title":"Nature"},{"key":"BF267544a0_CR14","first-page":"1628","volume":"35","author":"EH Frieden","year":"1976","unstructured":"Frieden, E. H. & Yeh, L. Fedn Proc. 35, 1628 (1976).","journal-title":"Fedn Proc."},{"key":"BF267544a0_CR15","first-page":"414","volume-title":"Growth Hormone and Related Peptides","author":"SCM Kwok","year":"1976","unstructured":"Kwok, S. C. M., McMurtry, J. P. & Bryant, G. D. in Growth Hormone and Related Peptides (eds Pecile, A. & Muller, E. E.) 414\u2013421 (Elsevier, New York, 1976)."},{"key":"BF267544a0_CR16","doi-asserted-by":"publisher","first-page":"461","DOI":"10.2337\/diab.21.2.S461","volume":"21","author":"RE Chance","year":"1972","unstructured":"Chance, R. E. Diabetes 21, Suppl. 2. 461\u2013467 (1972).","journal-title":"Diabetes"},{"key":"BF267544a0_CR17","doi-asserted-by":"publisher","first-page":"725","DOI":"10.2337\/diab.17.12.725","volume":"17","author":"DF Steiner","year":"1968","unstructured":"Steiner, D. F., Hallund, O., Rubenstein, A., Cho, S. & Bayliss, C. Diabetes 17, 725\u2013736 (1968).","journal-title":"Diabetes"},{"key":"BF267544a0_CR18","unstructured":"Rinderknecht, E. & Humbel, R. E. Proc. natn. Acad. Sci. U.S.A. 73 (in the press)."},{"key":"BF267544a0_CR19","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1126\/science.176.4034.482","volume":"176","author":"WA Frazier","year":"1972","unstructured":"Frazier, W. A., Hogue-Angeletti, R. & Bradshaw, R. A. Science 176, 482\u2013488 (1972).","journal-title":"Science"},{"key":"BF267544a0_CR20","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/B978-0-12-027308-9.50015-9","volume":"8","author":"JJ Van Wyk","year":"1975","unstructured":"Van Wyk, J. J. et al. Adv. Metab. Dis. 8, 127\u2013150 (1975).","journal-title":"Adv. Metab. Dis."},{"key":"BF267544a0_CR21","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1002\/jcp.1040840204","volume":"84","author":"G Smith","year":"1974","unstructured":"Smith, G. & Temin, H. M. J. cell. Physiol. 84, 181\u2013192 (1974).","journal-title":"J. cell. Physiol."},{"key":"BF267544a0_CR22","first-page":"89","volume-title":"Atlas of Protein Sequence and Structure","author":"MO Dayhoff","year":"1972","unstructured":"Dayhoff, M. O., Eck, R. V. & Park, C. M. in Atlas of Protein Sequence and Structure (ed Dayhoff, M. D.) 89\u201399 (National Biomedical Research Foundation, Washington 1972)."},{"key":"BF267544a0_CR23","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1016\/0006-291X(77)91070-1","volume":"75","author":"C Schwabe","year":"1977","unstructured":"Schwabe, C., McDonald, J. K. & Steinetz, B.G. Biochem biophys. Res. commun. 75, 503\u2013510 (1977).","journal-title":"Biochem biophys. Res. commun."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/267544a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/267544a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/267544a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T00:28:34Z","timestamp":1684283314000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/267544a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,6]]},"references-count":23,"journal-issue":{"issue":"5611","published-print":{"date-parts":[[1977,6]]}},"alternative-id":["BF267544a0"],"URL":"https:\/\/doi.org\/10.1038\/267544a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,6]]}}}