{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T16:11:49Z","timestamp":1772813509090,"version":"3.50.1"},"reference-count":100,"publisher":"Springer Science and Business Media LLC","issue":"5647","license":[{"start":{"date-parts":[[1978,2,1]],"date-time":"1978-02-01T00:00:00Z","timestamp":255139200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[1978,2,1]],"date-time":"1978-02-01T00:00:00Z","timestamp":255139200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1978,2,23]]},"DOI":"10.1038\/271713a0","type":"journal-article","created":{"date-parts":[[2005,8,2]],"date-time":"2005-08-02T16:44:59Z","timestamp":1123001099000},"page":"713-717","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":401,"title":["Repair deficient human disorders and cancer"],"prefix":"10.1038","volume":"271","author":[{"given":"R. B.","family":"Setlow","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[1978,2,1]]},"reference":[{"key":"BF271713a0_CR1","first-page":"61","volume":"8","author":"J German","year":"1972","unstructured":"German, J. Progr. Med. Genet. 8, 61\u2013101 (1972).","journal-title":"Progr. Med. Genet."},{"key":"BF271713a0_CR2","first-page":"619","volume-title":"Chromosomes and Cancer","author":"DG Harnden","year":"1974","unstructured":"Harnden, D. G. in Chromosomes and Cancer (ed. German, J.) 619\u2013636 (Wiley, New York, 1974)."},{"key":"BF271713a0_CR3","doi-asserted-by":"publisher","first-page":"221","DOI":"10.7326\/0003-4819-80-2-221","volume":"80","author":"JH Robbins","year":"1974","unstructured":"Robbins, J. H., Kraemer, K. H., Lutzner, M. A., Festoff, B. W. & Coon, H. G. Annls int. Med. 80, 221\u2013248 (1974).","journal-title":"Annls int. Med."},{"key":"BF271713a0_CR4","first-page":"490","volume":"37","author":"H Takabe","year":"1977","unstructured":"Takabe, H. et al. Cancer Res. 37, 490\u2013495 (1977).","journal-title":"Cancer Res."},{"key":"BF271713a0_CR5","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1038\/261195a0","volume":"261","author":"BA Bridges","year":"1976","unstructured":"Bridges, B. A. Nature 261, 195\u2013200 (1976).","journal-title":"Nature"},{"key":"BF271713a0_CR6","first-page":"129","volume-title":"Biology of Radiation Carcinogenesis","author":"VW Maher","year":"1976","unstructured":"Maher, V. W. & McCormick, J. J. in Biology of Radiation Carcinogenesis (eds Yuhas, J. M., Tennant, R. W. & Regan, J. D.) 129\u2013145 (Raven, New York, 1976)."},{"key":"BF271713a0_CR7","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1146\/annurev.ge.09.120175.000315","volume":"9","author":"JE Cleaver","year":"1975","unstructured":"Cleaver, J. E. & Bootsma, D. A. Rev. Genet. 9, 19\u201338 (1975).","journal-title":"A. Rev. Genet."},{"key":"BF271713a0_CR8","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1038\/230370a0","volume":"230","author":"M Swift","year":"1971","unstructured":"Swift, M. Nature 230, 370\u2013373 (1971).","journal-title":"Nature"},{"key":"BF271713a0_CR9","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1146\/annurev.bb.01.060172.001453","volume":"1","author":"RB Setlow","year":"1972","unstructured":"Setlow, R. B. & Setlow, J. K. A. Rev. Biophys Bioengng 1, 293\u2013346 (1972).","journal-title":"A. Rev. Biophys Bioengng"},{"key":"BF271713a0_CR10","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1146\/annurev.bi.44.070175.000315","volume":"44","author":"L Grossman","year":"1975","unstructured":"Grossman, L., Braun, A., Feldberg, R. & Mahler, I. A. Rev. Biochem. 44, 19\u201343 (1975).","journal-title":"A. Rev. Biochem."},{"key":"BF271713a0_CR11","unstructured":"Hart, R. W., Setlow, R. B. & Woodhead, A. D. Proc. natn. Acad. Sci. U.S.A. (in the press)."},{"key":"BF271713a0_CR12","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/0165-1161(77)90192-3","volume":"46","author":"BM Sutherland","year":"1977","unstructured":"Sutherland, B. M. & Oliver, R. Mutat. Res. 46, 159\u2013160 (1977).","journal-title":"Mutat. Res."},{"key":"BF271713a0_CR13","doi-asserted-by":"publisher","first-page":"4116","DOI":"10.1021\/bi00663a031","volume":"15","author":"A Braun","year":"1976","unstructured":"Braun, A., Radman, M. & Grossman, L. Biochemistry 15, 4116\u20134120 (1976).","journal-title":"Biochemistry"},{"key":"BF271713a0_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/B978-0-12-035404-7.50008-5","volume":"4","author":"JE Cleaver","year":"1974","unstructured":"Cleaver, J. E. Adv. Radiat. Biol. 4, 1\u201375 (1974).","journal-title":"Adv. Radiat. Biol."},{"key":"BF271713a0_CR15","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1038\/267081a0","volume":"267","author":"R Goth-Goldstein","year":"1977","unstructured":"Goth-Goldstein, R. Nature 267, 81\u201382 (1977).","journal-title":"Nature"},{"key":"BF271713a0_CR16","doi-asserted-by":"publisher","first-page":"2005","DOI":"10.1016\/0024-3205(74)90018-6","volume":"15","author":"AR Lehmann","year":"1975","unstructured":"Lehmann, A. R. Life Sci. 15, 2005\u20132016 (1975).","journal-title":"Life Sci."},{"key":"BF271713a0_CR17","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1128\/br.40.4.869-907.1976","volume":"40","author":"E Witkin","year":"1976","unstructured":"Witkin, E. Bact. Rev. 40, 869\u2013907 (1976).","journal-title":"Bact. Rev."},{"key":"BF271713a0_CR18","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1016\/S0006-291X(76)80204-5","volume":"72","author":"R Waters","year":"1976","unstructured":"Waters, R. & Regan, J. D. Biochem. biophys. Res. Commun. 72, 803\u2013807 (1976).","journal-title":"Biochem. biophys. Res. Commun."},{"key":"BF271713a0_CR19","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/0022-2836(76)90156-X","volume":"101","author":"NP Higgins","year":"1976","unstructured":"Higgins, N. P., Kato, K. & Strauss, B. J. molec. Biol. 101, 417\u2013425 (1976).","journal-title":"J. molec. Biol."},{"key":"BF271713a0_CR20","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/0027-5107(76)90058-0","volume":"37","author":"Y Fujiwara","year":"1976","unstructured":"Fujiwara, Y. & Tatsumi, M. Mutat. Res. 37, 91\u2013110 (1976).","journal-title":"Mutat. Res."},{"key":"BF271713a0_CR21","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1016\/0005-2787(76)90007-1","volume":"425","author":"R Meneghini","year":"1976","unstructured":"Meneghini, R. & Hanawalt, P. C. Biochim. biophys. Acta 425, 428\u2013437 (1976).","journal-title":"Biochim. biophys. Acta"},{"key":"BF271713a0_CR22","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1016\/S0006-3495(76)85764-5","volume":"16","author":"M Clarkson","year":"1976","unstructured":"Clarkson, M. & Hewitt, R. R. Biophys. J. 16, 1155\u20131164 (1976).","journal-title":"Biophys. J."},{"key":"BF271713a0_CR23","first-page":"904","volume":"37","author":"AR Lehmann","year":"1977","unstructured":"Lehmann, A. R., Kirk-Bell, S., Arlett, C. F., Harcourt, S. A., de WeerdKastelen, E. A., Keijzer, W. & Hall-Smith, P. Cancer Res. 37, 904\u2013910 (1977).","journal-title":"Cancer Res."},{"key":"BF271713a0_CR24","unstructured":"Setlow, R. B., Ahmed, F. E. & Grist, E. in Origins of Human Cancer (eds Hiatt, H. H., Watson, J. D. & Winsten, J. A.)(Cold Spring Harbor Laboratory New York, in the press)."},{"key":"BF271713a0_CR25","first-page":"848","volume":"36","author":"SM D' Ambrosio","year":"1977","unstructured":"D' Ambrosio, S. M. & Setlow, R. B. Fedn Proc. 36, 848 (1977).","journal-title":"Fedn Proc."},{"key":"BF271713a0_CR26","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1073\/pnas.74.3.1152","volume":"74","author":"S Meyn","year":"1977","unstructured":"Meyn, S., Rossman, T. & Troll, W. Proc. natn. Acad. Sci. U.S.A. 74 1152\u20131156 (1977).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF271713a0_CR27","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1038\/265347a0","volume":"265","author":"S Wolff","year":"1977","unstructured":"Wolff, S., Rodin, B. & Cleaver, J. E. Nature 265, 347\u2013349 (1977).","journal-title":"Nature"},{"key":"BF271713a0_CR28","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1111\/j.1751-1097.1972.tb06264.x","volume":"15","author":"HG Griggs","year":"1972","unstructured":"Griggs, H. G. & Bender, M. A. Photochem. Photobiol. 15, 517\u2013526 (1972).","journal-title":"Photochem. Photobiol."},{"key":"BF271713a0_CR29","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1111\/j.1469-1809.1956.tb01387.x","volume":"35","author":"JM Parrington","year":"1971","unstructured":"Parrington, J. M., Delhandy, J. D. A. & Baden, H. P. A. hum. Genet. 35, 149\u2013160 (1971).","journal-title":"A. hum. Genet."},{"key":"BF271713a0_CR30","unstructured":"Scott, E. L. & Straf, M. L. in Origins of Human Cancer (eds Hiatt, H. H., Watson, J. D. & Winsten, J. A.) (Cold Spring Harbor Laboratory, New York, in the Press)."},{"key":"BF271713a0_CR31","first-page":"1965","volume":"34","author":"RS Day III","year":"1974","unstructured":"Day, R. S. III Cancer Res. 34, 1965\u20131970 (1974).","journal-title":"Cancer Res."},{"key":"BF271713a0_CR32","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/0027-5107(73)90083-3","volume":"19","author":"MC Paterson","year":"1973","unstructured":"Paterson, M. C., Lohmann, P. H. M. & Sluyter, M. L. Mutat. Res. 19, 245\u2013256 (1973).","journal-title":"Mutat. Res."},{"key":"BF271713a0_CR33","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1007\/978-1-4613-4160-4_47","volume-title":"Research in Photobiology","author":"D Bootsma","year":"1977","unstructured":"Bootsma, D. in Research in Photobiology (ed. Castellani, A.) 455\u2013468 (Plenum, New York, 1977)."},{"key":"BF271713a0_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0074-7696(08)60076-5","volume":"45","author":"MW Lieberman","year":"1976","unstructured":"Lieberman, M. W. Int. Rev. Cytol. 45, 1\u201323 (1976).","journal-title":"Int. Rev. Cytol."},{"key":"BF271713a0_CR35","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1073\/pnas.73.1.39","volume":"73","author":"J Fornace Jr.","year":"1976","unstructured":"Fornace, J. Jr., Kohn, K. W. & Kann, H. E. Jr Proc. natn. Acad. Sci. U.S.A. 73, 39\u201343 (1976).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF271713a0_CR36","doi-asserted-by":"publisher","first-page":"2958","DOI":"10.1073\/pnas.74.7.2958","volume":"74","author":"K Tanaka","year":"1977","unstructured":"Tanaka, K., Hayakawa, H., Sekiguchi, M. & Okado, Y. Proc. natn. Acad. Sci. U.S.A. 74, 2958\u20132962 (1977).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF271713a0_CR37","doi-asserted-by":"publisher","first-page":"2757","DOI":"10.1073\/pnas.73.8.2757","volume":"73","author":"K Mortelmans","year":"1976","unstructured":"Mortelmans, K., Friedberg, E. C., Slor, H., Thomas, G. & Cleaver, J. E. Proc. natn. Acad. Sci. U.S.A. 73, 2757\u20132761 (1976).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF271713a0_CR38","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1038\/253748a0","volume":"253","author":"RS Day","year":"1975","unstructured":"Day, R. S. Nature 253, 748\u2013749 (1975).","journal-title":"Nature"},{"key":"BF271713a0_CR39","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1038\/261593a0","volume":"261","author":"VM Maher","year":"1976","unstructured":"Maher, V. M., Ouellette, L. M., Curren, R. D. & McCormick, J. J. Nature 261, 593\u2013595 (1976).","journal-title":"Nature"},{"key":"BF271713a0_CR40","doi-asserted-by":"publisher","first-page":"63","DOI":"10.2307\/3572983","volume":"40","author":"W Harm","year":"1969","unstructured":"Harm, W. Radiat. Res. 40, 63\u201369 (1969).","journal-title":"Radiat. Res."},{"key":"BF271713a0_CR41","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1038\/257132a0","volume":"257","author":"BM Sutherland","year":"1975","unstructured":"Sutherland, B. M. & Oliver, R. Nature 257, 132\u2013134 (1975).","journal-title":"Nature"},{"key":"BF271713a0_CR42","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1016\/0005-2787(76)90310-5","volume":"442","author":"BM Sutherland","year":"1976","unstructured":"Sutherland, B. M. & Oliver, R. Biochim. biophys. Acta 442, 358\u2013367 (1976).","journal-title":"Biochim. biophys. Acta"},{"key":"BF271713a0_CR43","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1038\/bjc.1977.93","volume":"35","author":"S Kondo","year":"1977","unstructured":"Kondo, S. Br. J. Cancer 35, 595\u2013601 (1977).","journal-title":"Br. J. Cancer"},{"key":"BF271713a0_CR44","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/S0065-230X(08)60545-X","volume":"23","author":"M Nagao","year":"1976","unstructured":"Nagao, M. & Sugimura, T. Adv. Cancer Res. 23, 131\u2013169 (1976).","journal-title":"Adv. Cancer Res."},{"key":"BF271713a0_CR45","unstructured":"Stich, H. F. in Origins of Human Cancer (eds Hiatt, H. H., Watson, J. D. & Winsten, J. A.) (Cold Spring Harbor Laboratory, New York, in the press)."},{"key":"BF271713a0_CR46","first-page":"362","volume":"33","author":"JE Cleaver","year":"1973","unstructured":"Cleaver, J. E. Cancer Res. 33, 362\u2013369 (1973).","journal-title":"Cancer Res."},{"key":"BF271713a0_CR47","first-page":"3318","volume":"34","author":"JD Regan","year":"1974","unstructured":"Regan, J. D. & Setlow, R. B. Cancer Res. 34, 3318\u20133325 (1974).","journal-title":"Cancer Res."},{"key":"BF271713a0_CR48","first-page":"103","volume-title":"Biology of Radiation Carcinogenesis","author":"JD Regan","year":"1976","unstructured":"Regan, J. D. & Setlow, R. B. in Biology of Radiation Carcinogenesis (eds Yuhas, J. M., Tennant, R. W. & Regan, J. D.) 103\u2013113 (Raven, New York, 1976)."},{"key":"BF271713a0_CR49","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1073\/pnas.73.4.1169","volume":"73","author":"Y Kuhnlein","year":"1976","unstructured":"Kuhnlein, Y., Penhoet, E. E. & Linn, S. Proc. natn. Acad. Sci. U.S.A. 73, 1169\u20131173 (1976).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF271713a0_CR50","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/0005-2787(76)90196-9","volume":"435","author":"AJ Fornace Jr","year":"1976","unstructured":"Fornace, A. J. Jr & Kohn, K. W. Biochim. biophys. Acta 435, 95\u2013103 (1976).","journal-title":"Biochim. biophys. Acta"},{"key":"BF271713a0_CR51","first-page":"55","volume":"30","author":"CW Dingman","year":"1976","unstructured":"Dingman, C. W. & Kakunaga, T. Int. J. Radiat. Biol. 30, 55\u201366 (1976).","journal-title":"Int. J. Radiat. Biol."},{"key":"BF271713a0_CR52","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/0165-1161(76)90153-9","volume":"38","author":"JD Regan","year":"1976","unstructured":"Regan, J. D., Setlow, R. B., Francis, A. A. & Lijinsky, W. Mutat. Res. 38, 293\u2013302 (1976).","journal-title":"Mutat. Res."},{"key":"BF271713a0_CR53","first-page":"2097","volume":"33","author":"MW Lieberman","year":"1973","unstructured":"Lieberman, M. W. & Poirier, M. C. Cancer Res. 33, 2097\u20132103 (1973).","journal-title":"Cancer Res."},{"key":"BF271713a0_CR54","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1111\/j.1751-1097.1977.tb07353.x","volume":"25","author":"JD Regan","year":"1976","unstructured":"Regan, J. D. & Setlow, R. B. Photochem. Photobiol. 25, 345\u2013346 (1976).","journal-title":"Photochem. Photobiol."},{"key":"BF271713a0_CR55","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/0027-5107(75)90206-7","volume":"33","author":"RS Day III","year":"1975","unstructured":"Day, R. S. III, Giuffrida, A. S. & Dingman, C. W. Mutat. Res. 33, 311\u2013320 (1975).","journal-title":"Mutat. Res."},{"key":"BF271713a0_CR56","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/0009-2797(77)90074-6","volume":"17","author":"RS Day III","year":"1977","unstructured":"Day, R. S. III & Dimattino, M. Chem.-Biol. Interact. 17, 89\u201397 (1977).","journal-title":"Chem.-Biol. Interact."},{"key":"BF271713a0_CR57","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/0027-5107(75)90298-5","volume":"27","author":"RS Day III","year":"1975","unstructured":"Day, R. S. III Mutat. Res. 27, 407\u2013409 (1975).","journal-title":"Mutat. Res."},{"key":"BF271713a0_CR58","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1016\/0022-2836(77)90227-3","volume":"113","author":"Y Fujiwara","year":"1977","unstructured":"Fujiwara, Y., Tatsumi, M. & Sasaki, M. S. J. molec. Biol. 113, 635\u2013649 (1977).","journal-title":"J. molec. Biol."},{"key":"BF271713a0_CR59","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1002\/1097-0142(197308)32:2<380::AID-CNCR2820320214>3.0.CO;2-2","volume":"32","author":"M Higurashi","year":"1973","unstructured":"Higurashi, M. & Conen, P. E. Cancer 32, 380\u2013383 (1973).","journal-title":"Cancer"},{"key":"BF271713a0_CR60","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1038\/258427a0","volume":"258","author":"AMR Taylor","year":"1975","unstructured":"Taylor, A. M. R. et al. Nature 258 427\u2013429 (1975).","journal-title":"Nature"},{"key":"BF271713a0_CR61","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/0005-2787(77)90213-1","volume":"474","author":"AR Lehmann","year":"1977","unstructured":"Lehmann, A. R. & Stevens, S. Biochim. biophys. Acta 474, 49\u201360 (1977).","journal-title":"Biochim. biophys. Acta"},{"key":"BF271713a0_CR62","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1007\/978-1-4613-4160-4_22","volume-title":"Research in Photobiology","author":"MC Paterson","year":"1977","unstructured":"Paterson, M. C., Smith, B. P., Knight, P. A. & Anderson, A. K. in Research in Photobiology (ed. Castellani, A.) 207\u2013218 (Plenum, New York, 1977)."},{"key":"BF271713a0_CR63","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1038\/261590a0","volume":"261","author":"DI Hoar","year":"1976","unstructured":"Hoar, D. I. & Sargent, P. Nature 261, 590\u2013592 (1976).","journal-title":"Nature"},{"key":"BF271713a0_CR64","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/0165-1161(77)90119-4","volume":"46","author":"CF Arlett","year":"1977","unstructured":"Arlett, C. F. Mutat. Res. 46, 106 (1977).","journal-title":"Mutat. Res."},{"key":"BF271713a0_CR65","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/0006-291X(77)91406-1","volume":"74","author":"DE Amacher","year":"1977","unstructured":"Amacher, D. E. & Lieberman, M. W. Biochem. biophys. Res. Commun. 74, 285\u2013290 (1977).","journal-title":"Biochem. biophys. Res. Commun."},{"key":"BF271713a0_CR66","first-page":"1829","volume":"33","author":"MS Sasaki","year":"1973","unstructured":"Sasaki, M. S. & Tonomura, A. Cancer Res. 33, 1829\u20131836 (1973).","journal-title":"Cancer Res."},{"key":"BF271713a0_CR67","first-page":"191","volume":"31","author":"AJ Rainbow","year":"1977","unstructured":"Rainbow, A. J. & Howes, M. Int. J. Radiat. Biol. 31, 191\u2013195 (1977).","journal-title":"Int. J. Radiat. Biol."},{"key":"BF271713a0_CR68","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1038\/250223a0","volume":"250","author":"PK Poon","year":"1974","unstructured":"Poon, P. K., O'Brien, R. L. & Parker, J. W. Nature 250, 223\u2013225 (1974).","journal-title":"Nature"},{"key":"BF271713a0_CR69","doi-asserted-by":"publisher","first-page":"1548","DOI":"10.1073\/pnas.74.4.1548","volume":"74","author":"FE Ahmed","year":"1977","unstructured":"Ahmed, F. E. & Setlow, R. B. Proc. natn. Acad. Sci. U.S.A. 74, 1548\u20131552 (1977).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF271713a0_CR70","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1001\/archopht.1975.01010020626012","volume":"93","author":"DA Newsome","year":"1975","unstructured":"Newsome, D. A., Kraemer, K. H. & Robbins, J. H. Archs Opthalmol. 93, 660\u2013662 (1975).","journal-title":"Archs Opthalmol."},{"key":"BF271713a0_CR71","doi-asserted-by":"publisher","first-page":"509","DOI":"10.2307\/3574332","volume":"68","author":"J Berliner","year":"1976","unstructured":"Berliner, J., Mello, R. S. & Norman, A. Radiat. Res. 68, 509\u2013513 (1976).","journal-title":"Radiat. Res."},{"key":"BF271713a0_CR72","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1038\/247035a0","volume":"247","author":"RJ Wilkins","year":"1974","unstructured":"Wilkins, R. J. & Hart, R. W. Nature 247, 35\u201336 (1974).","journal-title":"Nature"},{"key":"BF271713a0_CR73","first-page":"1397","volume":"36","author":"D Scudiero","year":"1976","unstructured":"Scudiero, D., Norin, A., Karren, P. & Strauss, B. Cancer Res. 36, 1397\u20131403 (1976).","journal-title":"Cancer Res."},{"key":"BF271713a0_CR74","first-page":"1930","volume":"36","author":"AH Chalmers","year":"1976","unstructured":"Chalmers, A. H., Lavin, M., Atisoontorkul, S., Mansbridge, J. & Kidson, C. Cancer Res. 36, 1930\u20131934 (1976).","journal-title":"Cancer Res."},{"key":"BF271713a0_CR75","doi-asserted-by":"publisher","first-page":"2169","DOI":"10.1073\/pnas.71.6.2169","volume":"71","author":"RW Hart","year":"1974","unstructured":"Hart, R. W. & Setlow, R. B. Proc. natn. Acad. Sci. U.S.A. 71, 2169\u20132173 (1974).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF271713a0_CR76","first-page":"3243","volume":"37","author":"RD Ley","year":"1977","unstructured":"Ley, R. D., Sedita, B. A., Grube, D. D. & Fry, R. J. M. Cancer Res. 37, 3243\u20133248 (1977).","journal-title":"Cancer Res."},{"key":"BF271713a0_CR77","first-page":"3599","volume":"35","author":"GT Bowden","year":"1975","unstructured":"Bowden, G. T., Trosko, J. E., Shapas, B. G. & Boutwell, R. K. Cancer Res. 35, 3599\u20133607 (1975).","journal-title":"Cancer Res."},{"key":"BF271713a0_CR78","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/0014-4827(77)90095-7","volume":"104","author":"L Peleg","year":"1976","unstructured":"Peleg, L., Raz, E. & Ben-Ishal, R. Expl Cell Res. 104, 301\u2013307 (1976).","journal-title":"Expl Cell Res."},{"key":"BF271713a0_CR79","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1016\/0014-4827(75)90276-1","volume":"96","author":"JJ Lampidis","year":"1975","unstructured":"Lampidis, J. J. & Shaiberger, G. E. Expl Cell Res. 96, 412\u2013416 (1975).","journal-title":"Expl Cell Res."},{"key":"BF271713a0_CR80","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/0027-5107(77)90138-5","volume":"43","author":"JF Remsen","year":"1977","unstructured":"Remsen, J. F. & Cerutti, P. A. Mutat. Res. 43, 139\u2013146 (1977).","journal-title":"Mutat. Res."},{"key":"BF271713a0_CR81","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1007\/BF00295817","volume":"32","author":"TM Schroeder","year":"1976","unstructured":"Schroeder, T. M., Tilgen, D., Kr\u00fcger, J. & Vogel, F. Hum. Genet. 32, 257\u2013288 (1976).","journal-title":"Hum. Genet."},{"key":"BF271713a0_CR82","doi-asserted-by":"publisher","first-page":"4066","DOI":"10.1073\/pnas.72.10.4066","volume":"72","author":"SA Latt","year":"1975","unstructured":"Latt, S. A., Stetten, G., Juergens, L. A., Buchanan, G. R. & Gerlad, P,S. Proc. natn. Acad. Sci. U.S.A. 72, 4066\u20134070 (1975).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF271713a0_CR83","doi-asserted-by":"publisher","first-page":"2419","DOI":"10.1073\/pnas.73.7.2419","volume":"73","author":"JF Remsen","year":"1976","unstructured":"Remsen, J. F. & Cerutti, P. A. Proc. natn. Acad. Sci. U.S.A. 73, 2419\u20132248 (1976).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF271713a0_CR84","first-page":"248","volume":"29","author":"J German","year":"1977","unstructured":"German, J., Schonberg, S., Louie, E. & Chaganti, R. S. K. Am. J. hum. Genet. 29, 248ndash;255 (1977).","journal-title":"Am. J. hum. Genet."},{"key":"BF271713a0_CR85","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1038\/265466a0","volume":"265","author":"F Gianelli","year":"1977","unstructured":"Gianelli, F., Benson, P. F., Pawsey, S. A. & Polani, P. E. Nature 265, 466\u2013469 (1977).","journal-title":"Nature"},{"key":"BF271713a0_CR86","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1073\/pnas.72.2.758","volume":"72","author":"H Hand","year":"1975","unstructured":"Hand, H. & German, J. Proc. natn. Acad. Sci. U.S.A. 72, 758\u2013762 (1975).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF271713a0_CR87","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1111\/1523-1747.ep12280225","volume":"54","author":"JE Cleaver","year":"1970","unstructured":"Cleaver, J. E. J. invest. Dermatol. 54, 181\u2013195 (1970).","journal-title":"J. invest. Dermatol."},{"key":"BF271713a0_CR88","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1111\/1523-1747.ep12541694","volume":"67","author":"B Lambert","year":"1976","unstructured":"Lambert, B., Ringborg, U. & Swanbeck, J. J. invest. Dermatol. 67, 594\u2013598 (1976).","journal-title":"J. invest. Dermatol."},{"key":"BF271713a0_CR89","doi-asserted-by":"publisher","first-page":"2496","DOI":"10.1073\/pnas.73.7.2496","volume":"73","author":"RW Pero","year":"1976","unstructured":"Pero, R. W., Bryngelsson, C., Mitelman, F., Thulin, T. & Norden, \u00c5. Proc. natn. Acad. Sci. U.S.A. 73, 2496\u20132500 (1976).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF271713a0_CR90","first-page":"80","volume":"46","author":"MH Wade","year":"1977","unstructured":"Wade, M. H., Chu, E. H. Y. & Schmickel, R. D. Mutat. Res. 46, 80 (1977).","journal-title":"Mutat. Res."},{"key":"BF271713a0_CR91","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1038\/266726a0","volume":"266","author":"RR Weichselbaum","year":"1977","unstructured":"Weichselbaum, R. R., Nove, J. & Little, J. B. Nature 266, 726\u2013727 (1977).","journal-title":"Nature"},{"key":"BF271713a0_CR92","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1148\/121.2.479","volume":"121","author":"RR Weichselbaum","year":"1976","unstructured":"Weichselbaum, R. R., Epstein, J. & Little, J. B. Radiology 121, 479\u2013482 (1976).","journal-title":"Radiology"},{"key":"BF271713a0_CR93","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1073\/pnas.70.4.977","volume":"70","author":"J Epstein","year":"1973","unstructured":"Epstein, J., Williams, J. R. & Little, J. B. Proc. natn. Acad. Sci. U.S.A. 70, 977\u2013981 (1973).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF271713a0_CR94","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1016\/S0006-291X(74)80058-6","volume":"59","author":"JD Regan","year":"1974","unstructured":"Regan, J. D. & Setlow, R. B. Biochem. biophys. Res. Commun. 59, 858\u2013864 (1974).","journal-title":"Biochem. biophys. Res. Commun."},{"key":"BF271713a0_CR95","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/0027-5107(76)90042-7","volume":"37","author":"MO Bradley","year":"1976","unstructured":"Bradley, M. O., Erickson, L. C. & Kohn, K. W. Mutat. Res. 37, 279\u2013292 (1976).","journal-title":"Mutat. Res."},{"key":"BF271713a0_CR96","first-page":"181","volume":"59","author":"MA Bender","year":"1974","unstructured":"Bender, M. A. & Rary, J. M. Radiat. Res. 59, 181 (1974).","journal-title":"Radiat. Res."},{"key":"BF271713a0_CR97","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1016\/0006-291X(77)90361-8","volume":"74","author":"AH Rainbow","year":"1977","unstructured":"Rainbow, A. H. & Howes, M. Biochem. biophys. Res. Commun. 74, 714\u2013719 (1977).","journal-title":"Biochem. biophys. Res. Commun."},{"key":"BF271713a0_CR98","doi-asserted-by":"publisher","first-page":"560","DOI":"10.2307\/3573725","volume":"56","author":"RB Painter","year":"1973","unstructured":"Painter, R. B., Clarkson, J. M. & Young, B. R. Radiat. Res. 56, 560\u2013564 (1973).","journal-title":"Radiat. Res."},{"key":"BF271713a0_CR99","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/0027-5107(74)90165-1","volume":"23","author":"JM Clarkson","year":"1974","unstructured":"Clarkson, J. M. & Painter, R. B. Mutat. Res. 23, 107\u2013112 (1974).","journal-title":"Mutat. Res."},{"key":"BF271713a0_CR100","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/0047-6374(76)90009-9","volume":"5","author":"RW Hart","year":"1976","unstructured":"Hart, R. W. & Setlow, R. B. Mech. Aging Devel. 5, 67\u201377 (1976).","journal-title":"Mech. Aging Devel."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/271713a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/271713a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/271713a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,18]],"date-time":"2022-04-18T23:07:47Z","timestamp":1650323267000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/271713a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,2,1]]},"references-count":100,"journal-issue":{"issue":"5647","published-print":{"date-parts":[[1978,2,23]]}},"alternative-id":["BF271713a0"],"URL":"https:\/\/doi.org\/10.1038\/271713a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,2,1]]},"assertion":[{"value":"1 February 1978","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}