{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:25:33Z","timestamp":1759541133899},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"5695","license":[{"start":{"date-parts":[[1979,2,1]],"date-time":"1979-02-01T00:00:00Z","timestamp":286675200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1979,2]]},"DOI":"10.1038\/277399a0","type":"journal-article","created":{"date-parts":[[2005,8,2]],"date-time":"2005-08-02T12:54:05Z","timestamp":1122987245000},"page":"399-400","source":"Crossref","is-referenced-by-count":39,"title":["Opiate antagonist reverses the cardiovascular effects of inhalation anaesthesia"],"prefix":"10.1038","volume":"277","author":[{"given":"J. O.","family":"ARNDT","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"FREYE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF277399a0_CR1","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1126\/science.982058","volume":"194","author":"BA Berkowitz","year":"1976","unstructured":"Berkowitz, B. A., Ngai, S. H. & Finck, A. D. Science 194, 967 (1976).","journal-title":"Science"},{"key":"BF277399a0_CR2","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1097\/00000542-197704000-00003","volume":"46","author":"AD Finck","year":"1977","unstructured":"Finck, A. D., Ngai, S. H. & Berkowitz, B. A. Anesthesiology 46, 241 (1977).","journal-title":"Anesthesiology"},{"key":"BF277399a0_CR3","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1097\/00000542-197605000-00008","volume":"44","author":"SH Ngai","year":"1976","unstructured":"Ngai, S. H., Berkowitz, B. A., Yang, J. C., Hempstead, J. & Spector, S. Anesthesiology 44, 398 (1976).","journal-title":"Anesthesiology"},{"key":"BF277399a0_CR4","doi-asserted-by":"publisher","first-page":"219","DOI":"10.2165\/00003088-197601030-00004","volume":"1","author":"BA Berkowitz","year":"1976","unstructured":"Berkowitz, B. A. Clin. Pharmacokinet. 1, 219 (1976).","journal-title":"Clin. Pharmacokinet."},{"key":"BF277399a0_CR5","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1097\/00000542-197807000-00002","volume":"49","author":"MH Harper","year":"1978","unstructured":"Harper, M. H., Winter, P. M., Johnson, B. H. & Eger, E. I. II. Anesthesiology 49, 3 (1978).","journal-title":"Anesthesiology"},{"key":"BF277399a0_CR6","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1097\/00000542-197807000-00003","volume":"49","author":"RA Smith","year":"1978","unstructured":"Smith, R. A., Wilson, M. & Miller, K. W. Anesthesiology 49, 6 (1978).","journal-title":"Anesthesiology"},{"key":"BF277399a0_CR7","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1097\/00000542-197807000-00004","volume":"49","author":"PB Benett","year":"1978","unstructured":"Benett, P. B. Anesthesiology 49, 9 (1978).","journal-title":"Anesthesiology"},{"key":"BF277399a0_CR8","first-page":"79","volume":"6","author":"A Herz","year":"1971","unstructured":"Herz, A. & Teschemacher, H. J. Adv. Drug Res. 6, 79 (1971).","journal-title":"Adv. Drug Res."},{"key":"BF277399a0_CR9","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1038\/245447a0","volume":"245","author":"MJ Kuhar","year":"1973","unstructured":"Kuhar, M. J., Pert, C. B. & Snyder, S. H. Nature 245, 447 (1973).","journal-title":"Nature"},{"key":"BF277399a0_CR10","doi-asserted-by":"publisher","first-page":"3729","DOI":"10.1073\/pnas.73.10.3729","volume":"73","author":"CB Pert","year":"1976","unstructured":"Pert, C. B., Kuhar, M. J. & Snyder, S. H. Proc. natn. Acad. Sci. U.S.A. 73, 3729 (1976).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF277399a0_CR11","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1016\/0028-3908(70)90004-3","volume":"9","author":"A Herz","year":"1970","unstructured":"Herz, A., Albus, K., Met\u0177s, J., Schubert, P. & Teschemacherm, H. Neuropharmacology 9, 539 (1970).","journal-title":"Neuropharmacology"},{"key":"BF277399a0_CR12","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1007\/BF00306105","volume":"22","author":"P Schubert","year":"1970","unstructured":"Schubert, P., Teschemacher, H., Kreutzberg, G. W. & Herz, A. Histochemie 22, 277 (1970).","journal-title":"Histochemie"},{"key":"BF277399a0_CR13","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/0006-8993(74)90731-8","volume":"80","author":"A Pert","year":"1974","unstructured":"Pert, A. & Yaksh, T. Brain Res. 80, 135 (1974).","journal-title":"Brain Res."},{"key":"BF277399a0_CR14","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/0304-3959(76)90080-4","volume":"2","author":"DJ Mayer","year":"1976","unstructured":"Mayer, D. J. & Price, D. D. Pain 2, 379 (1976).","journal-title":"Pain"},{"key":"BF277399a0_CR15","doi-asserted-by":"publisher","first-page":"2895","DOI":"10.1073\/pnas.73.8.2895","volume":"73","author":"HH Loh","year":"1976","unstructured":"Loh, H. H., Tseng, L. F., Wei, E. & Li, C. H. Proc. natn. Acad. Sci. U.S.A. 73, 2895 (1976).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF277399a0_CR16","first-page":"1081","volume":"119","author":"H Akil","year":"1976","unstructured":"Akil, H., Mayer, D. J. & Liebeskind, J. C. Science 119, 1081 (1976).","journal-title":"Science"},{"key":"BF277399a0_CR17","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1073\/pnas.74.2.774","volume":"74","author":"M Meglio","year":"1977","unstructured":"Meglio, M., Hosobuchi, Y., Loh, H. H., Adams, J. E. & Li, C. H. Proc. natn. Acad. Sci. U.S.A. 74, 774 (1977).","journal-title":"Proc. natn. Acad. Sci. U.S.A."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/277399a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/277399a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/277399a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T00:37:34Z","timestamp":1684283854000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/277399a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,2]]},"references-count":17,"journal-issue":{"issue":"5695","published-print":{"date-parts":[[1979,2]]}},"alternative-id":["BF277399a0"],"URL":"https:\/\/doi.org\/10.1038\/277399a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,2]]}}}