{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T10:13:06Z","timestamp":1775815986978,"version":"3.50.1"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"5757","license":[{"start":{"date-parts":[[1980,4,1]],"date-time":"1980-04-01T00:00:00Z","timestamp":323395200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1980,4]]},"DOI":"10.1038\/284632a0","type":"journal-article","created":{"date-parts":[[2004,11,17]],"date-time":"2004-11-17T17:52:26Z","timestamp":1100713946000},"page":"632-635","source":"Crossref","is-referenced-by-count":109,"title":["A novel \u03b1-globin gene arrangement in man"],"prefix":"10.1038","volume":"284","author":[{"given":"D. R.","family":"Higgs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"Old","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Pressley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. B.","family":"Clegg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. J.","family":"Weatherall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF284632a0_CR1","unstructured":"Hunt, D. M. et al. Br. J. Haemat. (in the press)."},{"key":"BF284632a0_CR2","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/0092-8674(79)90292-7","volume":"17","author":"SH Orkin","year":"1979","unstructured":"Orkin, S. H. et al. Cell. 17, 33\u201342 (1979).","journal-title":"Cell."},{"key":"BF284632a0_CR3","first-page":"1439","volume":"54","author":"JA Phillips","year":"1979","unstructured":"Phillips, J. A. III et al. Blood 54, 1439\u20131445 (1979).","journal-title":"Blood"},{"key":"BF284632a0_CR4","doi-asserted-by":"publisher","first-page":"1880","DOI":"10.1073\/pnas.48.11.1880","volume":"48","author":"C Baglioni","year":"1962","unstructured":"Baglioni, C. Proc. natn. Acad. Sci. U.S.A. 48, 1880\u20131886 (1962).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF284632a0_CR5","doi-asserted-by":"publisher","first-page":"5950","DOI":"10.1073\/pnas.75.12.5950","volume":"75","author":"SH Orkin","year":"1978","unstructured":"Orkin, S. H. Proc. natn. Acad. Sci. U.S.A. 75, 5950\u20135954 (1978).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF284632a0_CR6","doi-asserted-by":"publisher","first-page":"1307","DOI":"10.1172\/JCI109426","volume":"63","author":"SH Embury","year":"1979","unstructured":"Embury, S. H. et al. J. Clin. Invest. 63, 1307\u20131310 (1979).","journal-title":"J. Clin. Invest."},{"key":"BF284632a0_CR7","volume-title":"The Thalassaemia Syndromes","author":"DJ Weatherall","year":"1972","unstructured":"Weatherall, D. J. & Clegg, J. B. The Thalassaemia Syndromes 2nd edn (Blackwell, Oxford, 1972)."},{"key":"BF284632a0_CR8","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1056\/NEJM196912112812403","volume":"281","author":"E Schwartz","year":"1969","unstructured":"Schwartz, E. New Engl. J. Med. 281, 1327\u20131333 (1969).","journal-title":"New Engl. J. Med."},{"key":"BF284632a0_CR9","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1111\/j.1432-1033.1973.tb02881.x","volume":"36","author":"M Gross-Bellard","year":"1973","unstructured":"Gross-Bellard, M., Oudet, P. & Chambon, P. Eur. J. Biochem. 36, 21\u201338 (1973).","journal-title":"Eur. J. Biochem."},{"key":"BF284632a0_CR10","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1016\/S0022-2836(75)80083-0","volume":"98","author":"EM Southern","year":"1975","unstructured":"Southern, E. M. J. molec. Biol 98, 503\u2013517 (1975).","journal-title":"J. molec. Biol"},{"key":"BF284632a0_CR11","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1093\/nar\/5.2.563","volume":"5","author":"JT Wilson","year":"1978","unstructured":"Wilson, J. T. et al. Nucleic Acids Res. 5, 563\u2013581 (1978).","journal-title":"Nucleic Acids Res."},{"key":"BF284632a0_CR12","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.1073\/pnas.72.3.1184","volume":"72","author":"T Maniatis","year":"1975","unstructured":"Maniatis, T., Jeffrey, A. & Kleid, D. G. Proc. natn. Acad. Sci. U.S.A. 72, 1184\u20131188 (1975).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF284632a0_CR13","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/0014-5793(77)80609-1","volume":"82","author":"RA Laskey","year":"1977","unstructured":"Laskey, R. A., & Mills, A. D. FEBS Lett. 82, 314\u2013316 (1977).","journal-title":"FEBS Lett."},{"key":"BF284632a0_CR14","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1038\/2081061a0","volume":"208","author":"DJ Weatherall","year":"1965","unstructured":"Weatherall, D. J., Clegg, J. B. & Naughton, M. A. Nature 208, 1061\u20131065 (1965).","journal-title":"Nature"},{"key":"BF284632a0_CR15","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1073\/pnas.77.1.518","volume":"77","author":"M Goossens","year":"1980","unstructured":"Goossens, M. et al. Proc. natn. Acad. Sci. U.S.A. 77, 518\u2013521 (1980).","journal-title":"Proc. natn. Acad. Sci. U.S.A."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/284632a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/284632a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/284632a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T00:33:22Z","timestamp":1684283602000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/284632a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,4]]},"references-count":15,"journal-issue":{"issue":"5757","published-print":{"date-parts":[[1980,4]]}},"alternative-id":["BF284632a0"],"URL":"https:\/\/doi.org\/10.1038\/284632a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,4]]}}}