{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T08:57:30Z","timestamp":1762160250166},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"5809","license":[{"start":{"date-parts":[[1981,4,1]],"date-time":"1981-04-01T00:00:00Z","timestamp":354931200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1981,4]]},"DOI":"10.1038\/290787a0","type":"journal-article","created":{"date-parts":[[2004,11,17]],"date-time":"2004-11-17T19:20:18Z","timestamp":1100719218000},"page":"787-789","source":"Crossref","is-referenced-by-count":112,"title":["Acceleration of \u03b2-receptor desensitization in combined administration of antidepressants and phenoxybenzamine"],"prefix":"10.1038","volume":"290","author":[{"given":"Fulton T.","family":"Crews","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven M.","family":"Paul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederick K.","family":"Goodwin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF290787a0_CR1","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1192\/bjp.120.559.673","volume":"120","author":"I Oswald","year":"1972","unstructured":"Oswald, I., Brezinova, V. & Dunleavy, D. L. F. Br. J. Psychiat. 120, 673\u2013677 (1972).","journal-title":"Br. J. Psychiat."},{"key":"BF290787a0_CR2","unstructured":"Klein, D. F. & Davis, J. M. Diagnosis and Drug Treatment of Psychiatric Disorders (Williams & Wilkins, Baltimore, 1969)."},{"key":"BF290787a0_CR3","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/0006-2952(78)90226-5","volume":"27","author":"F Sulser","year":"1978","unstructured":"Sulser, F., Vetulani, J. & Mobley, P. L. Biochem. Pharmac. 27, 257\u2013261 (1978).","journal-title":"Biochem. Pharmac."},{"key":"BF290787a0_CR4","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1038\/268455a0","volume":"268","author":"SP Banerjee","year":"1977","unstructured":"Banerjee, S. P., King, L. S., Riggi, S. J. & Chanda, S. K. Nature 268, 455\u2013456 (1977).","journal-title":"Nature"},{"key":"BF290787a0_CR5","first-page":"592","volume":"28","author":"MM Sellinger","year":"1979","unstructured":"Sellinger, M. M., Frayer, A. & Mendels, J. Fedn Proc. 28, 592 (1979).","journal-title":"Fedn Proc."},{"key":"BF290787a0_CR6","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1007\/BF00499215","volume":"293","author":"J Vetulani","year":"1976","unstructured":"Vetulani, J., Stawary, R. J., Dingell, J. V. & Sulser, F. Naunyn-Schmiedebergs Archs Pharmak. 293, 109\u2013114 (1976).","journal-title":"Naunyn-Schmiedebergs Archs Pharmak."},{"key":"BF290787a0_CR7","first-page":"446","volume":"207","author":"BB Wolfe","year":"1978","unstructured":"Wolfe, B. B., Harden, T. K., Sporn, J. R. & Molinoff, P. B. J. Pharmac. exp. Ther. 207, 446\u2013457 (1978).","journal-title":"J. Pharmac. exp. Ther."},{"key":"BF290787a0_CR8","unstructured":"Crews, F. T. & Smith, C. B., 202, 322\u2013324 (1978)."},{"key":"BF290787a0_CR9","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/0014-2999(80)90104-1","volume":"62","author":"S Paul","year":"1980","unstructured":"Paul, S. & Crews, F. T. Eur. J. Pharmac. 62, 349\u2013350 (1980).","journal-title":"Eur. J. Pharmac."},{"key":"BF290787a0_CR10","first-page":"368","volume":"188","author":"LX Cubeddu","year":"1974","unstructured":"Cubeddu, L. X., Langer, S. Z. & Weiner, N. J. Pharmac. exp. Ther. 188, 368\u2013385 (1974).","journal-title":"J. Pharmac. exp. Ther."},{"key":"BF290787a0_CR11","first-page":"568","volume":"12","author":"DB Bylund","year":"1976","unstructured":"Bylund, D. B. & Snyder, S. H. Molec. Pharmac. 12, 568\u2013580 (1976).","journal-title":"Molec. Pharmac."},{"key":"BF290787a0_CR12","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/0014-2999(75)90297-6","volume":"32","author":"H Nyback","year":"1975","unstructured":"Nyback, H., Walters, J. R., Aghajanian, G. K. & Roth, R. H. Eur. J. Pharmac. 32, 302\u2013312 (1975).","journal-title":"Eur. J. Pharmac."},{"key":"BF290787a0_CR13","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1126\/science.213833","volume":"202","author":"TH Svensson","year":"1978","unstructured":"Svensson, T. H. & Usdin, T. Science 202, 1089\u20131091 (1978).","journal-title":"Science"},{"key":"BF290787a0_CR14","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/0014-2999(80)90019-9","volume":"67","author":"RW Johnson","year":"1980","unstructured":"Johnson, R. W. et al. Eur. J. Pharmac. 67, 123\u2013127 (1980).","journal-title":"Eur. J. Pharmac."},{"key":"BF290787a0_CR15","unstructured":"Maggi, A., U'Prichard, D. C. & Enna, S. J., 207, 645\u2013647 (1980)."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/290787a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/290787a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/290787a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T00:20:44Z","timestamp":1684282844000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/290787a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,4]]},"references-count":15,"journal-issue":{"issue":"5809","published-print":{"date-parts":[[1981,4]]}},"alternative-id":["BF290787a0"],"URL":"https:\/\/doi.org\/10.1038\/290787a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,4]]}}}