{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T20:29:15Z","timestamp":1784752155344,"version":"3.55.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"5936","license":[{"start":{"date-parts":[[1983,10,1]],"date-time":"1983-10-01T00:00:00Z","timestamp":433814400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1983,10]]},"DOI":"10.1038\/305738a0","type":"journal-article","created":{"date-parts":[[2004,11,18]],"date-time":"2004-11-18T01:13:14Z","timestamp":1100740394000},"page":"738-740","source":"Crossref","is-referenced-by-count":94,"title":["Elevation of tubulin levels by microinjection suppresses new tubulin synthesis"],"prefix":"10.1038","volume":"305","author":[{"given":"Don W.","family":"Cleveland","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark F.","family":"Pittenger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James R.","family":"Feramisco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF305738a0_CR1","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/0092-8674(79)90157-0","volume":"17","author":"A Ben Ze'ev","year":"1979","unstructured":"Ben Ze'ev, A., Farmer, S. R. & Penman, S. Cell 17, 319\u2013325 (1979).","journal-title":"Cell"},{"key":"BF305738a0_CR2","doi-asserted-by":"crossref","unstructured":"Cleveland, D. W., Lopata, M. A., Sherline, P. & Kirschner, M. W. Cell 25, 537\u2013546.","DOI":"10.1016\/0092-8674(81)90072-6"},{"key":"BF305738a0_CR3","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1101\/SQB.1982.046.01.020","volume":"44","author":"DW Cleveland","year":"1982","unstructured":"Cleveland, D. W. & Kirschner, M. W. Cold Spring Harb. Symp. quant. Biol. 44, 171\u2013183 (1982).","journal-title":"Cold Spring Harb. Symp. quant. Biol."},{"key":"BF305738a0_CR4","first-page":"353","volume":"15","author":"DW Cleveland","year":"1983","unstructured":"Cleveland, D. W., Pittenger, M. F. & Lopata, M. A. J. submicrosc. Cytol. 15, 353\u2013358 (1983).","journal-title":"J. submicrosc. Cytol."},{"key":"BF305738a0_CR5","doi-asserted-by":"publisher","first-page":"1858","DOI":"10.1073\/pnas.72.5.1858","volume":"72","author":"MD Weingarten","year":"1975","unstructured":"Weingarten, M. D., Lockwood, A. H., Hwo, S.-Y. & Kirschner, M. W. Proc. natn. Acad. Sci. USA 72, 1858\u20131862 (1975).","journal-title":"Proc. natn. Acad. Sci. USA"},{"key":"BF305738a0_CR6","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1016\/0092-8674(78)90335-5","volume":"14","author":"G Hiller","year":"1978","unstructured":"Hiller, G. & Weber, K. Cell 14, 795\u2013804 (1978).","journal-title":"Cell"},{"key":"BF305738a0_CR7","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/0092-8674(77)90259-8","volume":"12","author":"BM Spiegelman","year":"1977","unstructured":"Spiegelman, B. M., Penningroth, S. M. & Kirschner, M. W. Cell 12, 587\u2013595 (1977).","journal-title":"Cell"},{"key":"BF305738a0_CR8","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1083\/jcb.89.3.418","volume":"89","author":"JB Olmsted","year":"1981","unstructured":"Olmsted, J. B. J. Cell Biol. 89, 418\u2013423 (1981).","journal-title":"J. Cell Biol."},{"key":"BF305738a0_CR9","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1016\/S0076-6879(80)65076-9","volume":"65","author":"A Graessmann","year":"1980","unstructured":"Graessmann, A., Graessmann, M. & Mueller, C. Meth. Enzym. 65, 816\u2013825 (1980).","journal-title":"Meth. Enzym."},{"key":"BF305738a0_CR10","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1016\/0092-8674(76)90136-7","volume":"9","author":"DW Stacey","year":"1976","unstructured":"Stacey, D. W. & Allfrey, V. G. Cell 9, 729\u2013737 (1976).","journal-title":"Cell"},{"key":"BF305738a0_CR11","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/0022-2836(77)90213-3","volume":"116","author":"DW Cleveland","year":"1977","unstructured":"Cleveland, D. W., Hwo, S.-Y. & Kirschner, M. W. J. molec. Biol. 116, 207\u2013225 (1977).","journal-title":"J. molec. Biol."},{"key":"BF305738a0_CR12","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/S0022-2836(75)80144-6","volume":"99","author":"MW Kirschner","year":"1975","unstructured":"Kirschner, M. W., Honig, L. & Williams, R. C. J. molec. Biol. 99, 263\u2013276 (1975).","journal-title":"J. molec. Biol."},{"key":"BF305738a0_CR13","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1038\/227680a0","volume":"227","author":"UK Laemmli","year":"1970","unstructured":"Laemmli, U. K. Nature 227, 680\u2013685 (1970).","journal-title":"Nature"},{"key":"BF305738a0_CR14","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1073\/pnas.70.3.765","volume":"70","author":"ML Shelanski","year":"1973","unstructured":"Shelanski, M. L., Gaskin, F. & Cantor, C. R. Proc. natn. Acad. Sci. U.S.A. 70, 765\u2013768 (1973).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF305738a0_CR15","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1016\/0076-6879(82)85050-7","volume":"85","author":"K Wang","year":"1982","unstructured":"Wang, K., Feramisco, J. R. & Ash, J. F. Meth. Enzym. 85, 514\u2013534 (1982).","journal-title":"Meth. Enzym."},{"key":"BF305738a0_CR16","doi-asserted-by":"crossref","first-page":"4007","DOI":"10.1016\/S0021-9258(19)41496-8","volume":"250","author":"PO O'Farrell","year":"1975","unstructured":"O'Farrell, P. O. J. biol. Chem. 250, 4007\u20134021 (1975).","journal-title":"J. biol. Chem."},{"key":"BF305738a0_CR17","doi-asserted-by":"crossref","unstructured":"Bonner, W. M. & Laskey, R. A. Eur. J. Biochem. 46, 83\u201388.","DOI":"10.1111\/j.1432-1033.1974.tb03599.x"}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/305738a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/305738a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/305738a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T00:57:53Z","timestamp":1684285073000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/305738a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,10]]},"references-count":17,"journal-issue":{"issue":"5936","published-print":{"date-parts":[[1983,10]]}},"alternative-id":["BF305738a0"],"URL":"https:\/\/doi.org\/10.1038\/305738a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,10]]}}}