{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T04:28:13Z","timestamp":1784089693901,"version":"3.55.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"6174","license":[{"start":{"date-parts":[[1988,6,1]],"date-time":"1988-06-01T00:00:00Z","timestamp":581126400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1988,6]]},"DOI":"10.1038\/333635a0","type":"journal-article","created":{"date-parts":[[2003,6,12]],"date-time":"2003-06-12T21:57:37Z","timestamp":1055455057000},"page":"635-640","source":"Crossref","is-referenced-by-count":246,"title":["Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein"],"prefix":"10.1038","volume":"333","author":[{"given":"Ian A.","family":"Hope","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subramony","family":"Mahadevan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Struhl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF333635a0_CR1","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1016\/0092-8674(86)90061-9","volume":"46","author":"SL McKnight","year":"1986","unstructured":"McKnight, S. L. & Tjian, R. Cell 46, 795\u2013805 (1986).","journal-title":"Cell"},{"key":"BF333635a0_CR2","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/0092-8674(87)90277-7","volume":"49","author":"K Struhl","year":"1987","unstructured":"Struhl, K. Cell 49, 295\u2013297 (1987).","journal-title":"Cell"},{"key":"BF333635a0_CR3","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1146\/annurev.ge.21.120187.002233","volume":"21","author":"L Guarente","year":"1987","unstructured":"Guarente, L. A. Rev. Genet. 21, 425\u2013452 (1987).","journal-title":"A. Rev. Genet."},{"key":"BF333635a0_CR4","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1126\/science.3080805","volume":"231","author":"L Keegan","year":"1986","unstructured":"Keegan, L., Gill, G. & Ptashne, M. Science 231, 699\u2013704 (1986).","journal-title":"Science"},{"key":"BF333635a0_CR5","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1016\/0092-8674(86)90070-X","volume":"46","author":"IA Hope","year":"1986","unstructured":"Hope, I. A. & Struhl, K. Cell 46, 885\u2013894 (1986).","journal-title":"Cell"},{"key":"BF333635a0_CR6","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/0092-8674(87)90753-7","volume":"49","author":"SM Hollenberg","year":"1987","unstructured":"Hollenberg, S. M., Giguere, V., Segui, P. & Evans, R. M. Cell 49, 39\u201346 (1987).","journal-title":"Cell"},{"key":"BF333635a0_CR7","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1126\/science.3563519","volume":"236","author":"R Miesfeld","year":"1987","unstructured":"Miesfeld, R., Godowski, P., Maler, B. & Yamamoto, K. Science 236, 423\u2013427 (1987).","journal-title":"Science"},{"key":"BF333635a0_CR8","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1016\/0092-8674(87)90581-2","volume":"51","author":"V Kumar","year":"1987","unstructured":"Kumar, V. et al. Cell 51, 941\u2013951 (1987).","journal-title":"Cell"},{"key":"BF333635a0_CR9","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1016\/0092-8674(85)90246-6","volume":"43","author":"R Brent","year":"1985","unstructured":"Brent, R. & Ptashne, M. Cell 43, 729\u2013736 (1985).","journal-title":"Cell"},{"key":"BF333635a0_CR10","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1016\/0092-8674(87)90081-X","volume":"48","author":"J Ma","year":"1987","unstructured":"Ma, J. & Ptashne, M. Cell 48, 847\u2013853 (1987).","journal-title":"Cell"},{"key":"BF333635a0_CR11","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/0092-8674(87)90015-8","volume":"51","author":"J Ma","year":"1987","unstructured":"Ma, J. & Ptashne, M. Cell 51, 113\u2013119 (1987).","journal-title":"Cell"},{"key":"BF333635a0_CR12","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/0092-8674(87)90016-X","volume":"51","author":"G Gill","year":"1987","unstructured":"Gill, G. & Ptashne, M. Cell 51, 121\u2013126 (1987).","journal-title":"Cell"},{"key":"BF333635a0_CR13","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.1126\/science.2825349","volume":"238","author":"D Bohmann","year":"1987","unstructured":"Bohmann, D. et al. Science 238, 1386\u20131392 (1987).","journal-title":"Science"},{"key":"BF333635a0_CR14","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1038\/332166a0","volume":"332","author":"P Angel","year":"1988","unstructured":"Angel, P. et al. Nature 332, 166\u2013171 (1988).","journal-title":"Nature"},{"key":"BF333635a0_CR15","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1038\/332649a0","volume":"332","author":"K Struhl","year":"1988","unstructured":"Struhl, K. Nature 332, 649\u2013650 (1988).","journal-title":"Nature"},{"key":"BF333635a0_CR16","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/0092-8674(85)90022-4","volume":"43","author":"IA Hope","year":"1985","unstructured":"Hope, I. A. & Struhl, K. Cell 43, 177\u2013188 (1985).","journal-title":"Cell"},{"key":"BF333635a0_CR17","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1002\/j.1460-2075.1986.tb04364.x","volume":"5","author":"G vonHeijne","year":"1986","unstructured":"vonHeijne, G. EMBO J. 5, 1335\u20131342 (1986).","journal-title":"EMBO J."},{"key":"BF333635a0_CR18","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1002\/j.1460-2075.1986.tb04363.x","volume":"5","author":"D Roise","year":"1986","unstructured":"Roise, D., Horvath, S. J., Tomich, J. M., Richards, J. H. & Schatz, G. EMBO J. 5, 1327\u20131334 (1986).","journal-title":"EMBO J."},{"key":"BF333635a0_CR19","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1038\/330670a0","volume":"330","author":"E Giniger","year":"1987","unstructured":"Giniger, E. & Ptashne, M. Nature 330, 670\u2013672 (1987).","journal-title":"Nature"},{"key":"BF333635a0_CR20","doi-asserted-by":"publisher","first-page":"2781","DOI":"10.1002\/j.1460-2075.1987.tb02573.x","volume":"6","author":"IA Hope","year":"1987","unstructured":"Hope, I. A. & Struhl, K., EMBO J. 6, 2781\u20132784 (1987).","journal-title":"EMBO J."},{"key":"BF333635a0_CR21","doi-asserted-by":"publisher","first-page":"2301","DOI":"10.1073\/pnas.82.8.2301","volume":"82","author":"JW Little","year":"1985","unstructured":"Little, J. W. & Hill, S. A. Proc. natn. Acad. Sci. U.S.A. 82, 2301\u20132305 (1985).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF333635a0_CR22","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1002\/j.1460-2075.1988.tb02809.x","volume":"7","author":"S Hurstel","year":"1988","unstructured":"Hurstel, S., Granger-Schnarr, M. & Schnarr, M. EMBO J. 7, 269\u2013275 (1988).","journal-title":"EMBO J."},{"key":"BF333635a0_CR23","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1016\/0092-8674(87)90511-3","volume":"50","author":"K Struhl","year":"1987","unstructured":"Struhl, K. Cell 50, 841\u2013846 (1987).","journal-title":"Cell"},{"key":"BF333635a0_CR24","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1016\/0092-8674(87)90171-1","volume":"50","author":"W Chen","year":"1987","unstructured":"Chen, W., Tabor, S. & Struhl, K. Cell 50, 1047\u20131055 (1987).","journal-title":"Cell"},{"key":"BF333635a0_CR25","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1126\/science.3532321","volume":"234","author":"DE Hill","year":"1986","unstructured":"Hill, D. E., Hope, I. A., Macke, J. P. & Struhl, K. Science 234, 451\u2013457 (1986).","journal-title":"Science"}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/333635a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/333635a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/333635a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T01:38:12Z","timestamp":1684287492000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/333635a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,6]]},"references-count":25,"journal-issue":{"issue":"6174","published-print":{"date-parts":[[1988,6]]}},"alternative-id":["BF333635a0"],"URL":"https:\/\/doi.org\/10.1038\/333635a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,6]]}}}