{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T12:13:45Z","timestamp":1779279225153,"version":"3.51.4"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"6297","license":[{"start":{"date-parts":[[1990,11,1]],"date-time":"1990-11-01T00:00:00Z","timestamp":657417600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1990,11]]},"DOI":"10.1038\/348169a0","type":"journal-article","created":{"date-parts":[[2003,6,12]],"date-time":"2003-06-12T22:56:06Z","timestamp":1055458566000},"page":"169-171","source":"Crossref","is-referenced-by-count":165,"title":["Limitation of the size of the vulval primordium of Caenorhabditis elegans by lin-15 expression in surrounding hypodermis"],"prefix":"10.1038","volume":"348","author":[{"given":"Robert K.","family":"Herman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward M.","family":"Hedgecock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF348169a0_CR1","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1016\/0012-1606(80)90353-X","volume":"78","author":"JE Sulston","year":"1980","unstructured":"Sulston, J. E. & White, J. G. Devl Biol. 78, 577\u2013597 (1980).","journal-title":"Devl Biol."},{"key":"BF348169a0_CR2","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1016\/0092-8674(86)90842-1","volume":"44","author":"P Sternberg","year":"1986","unstructured":"Sternberg, P. & Horvitz, H. R. Cell 44, 761\u2013772 (1986).","journal-title":"Cell"},{"key":"BF348169a0_CR3","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/0012-1606(77)90158-0","volume":"56","author":"JE Sulston","year":"1977","unstructured":"Sulston, J. E. & Horvitz, H. R. Devl Biol. 56, 110\u2013156 (1977).","journal-title":"Devl Biol."},{"key":"BF348169a0_CR4","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/0012-1606(81)90152-4","volume":"87","author":"J Kimble","year":"1981","unstructured":"Kimble, J. Devl Biol. 87, 286\u2013300 (1981).","journal-title":"Devl Biol."},{"key":"BF348169a0_CR5","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/genetics\/110.1.17","volume":"110","author":"E Ferguson","year":"1985","unstructured":"Ferguson, E. & Horvitz, H. R. Genetics 110, 17\u201372 (1985).","journal-title":"Genetics"},{"key":"BF348169a0_CR6","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/326259a0","volume":"326","author":"E Ferguson","year":"1987","unstructured":"Ferguson, E., Sternberg, P. W. & Horvitz, H. R. Nature 326, 259\u2013269 (1987).","journal-title":"Nature"},{"key":"BF348169a0_CR7","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1093\/genetics\/123.1.109","volume":"123","author":"E Ferguson","year":"1989","unstructured":"Ferguson, E. & Horvitz, H. R. Genetics 123, 109\u2013121 (1989).","journal-title":"Genetics"},{"key":"BF348169a0_CR8","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1016\/0092-8674(89)90103-7","volume":"58","author":"PW Sternberg","year":"1989","unstructured":"Sternberg, P. W. & Horvitz, H. R. Cell 58, 679\u2013693 (1989).","journal-title":"Cell"},{"key":"BF348169a0_CR9","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1016\/0092-8674(83)90377-X","volume":"34","author":"IS Greenwald","year":"1983","unstructured":"Greenwald, I. S., Sternberg, P. W. & Horvitz, H. R. Cell 34, 435\u2013444 (1983).","journal-title":"Cell"},{"key":"BF348169a0_CR10","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1038\/335551a0","volume":"335","author":"PW Sternberg","year":"1988","unstructured":"Sternberg, P. W. Nature 335, 551\u2013554 (1988).","journal-title":"Nature"},{"key":"BF348169a0_CR11","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1093\/genetics\/108.1.165","volume":"108","author":"RK Herman","year":"1984","unstructured":"Herman, R. K. Genetics 108, 165\u2013180 (1984).","journal-title":"Genetics"},{"key":"BF348169a0_CR12","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/0012-1606(83)90201-4","volume":"100","author":"JE Sulston","year":"1983","unstructured":"Sulston, J. E., Schierenberg, E., White, J. G. & Thomson, J. N. Devl Biol. 100, 64\u2013119 (1983).","journal-title":"Devl Biol."},{"key":"BF348169a0_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3109\/01677068909167261","volume":"5","author":"RK Herman","year":"1989","unstructured":"Herman, R. K., J. Neurogenet. 5, 1\u201324 (1989).","journal-title":"J. Neurogenet."},{"key":"BF348169a0_CR14","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1101\/gad.4.3.357","volume":"4","author":"SK Kim","year":"1990","unstructured":"Kim, S. K. & Horvitz, H. R. Genes Dev. 4, 357\u2013371 (1990).","journal-title":"Genes Dev."},{"key":"BF348169a0_CR15","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1101\/SQB.1985.050.01.014","volume":"50","author":"W Fixsen","year":"1985","unstructured":"Fixsen, W., Sternberg, P., Ellis, H. & Horvitz, R. Cold Spring Harb. Symp. quant. Biol. 50, 99\u2013104 (1985).","journal-title":"Cold Spring Harb. Symp. quant. Biol."},{"key":"BF348169a0_CR16","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/0092-8674(90)90722-Q","volume":"60","author":"DA Waring","year":"1990","unstructured":"Waring, D. A. & Kenyon, C. Cell 60, 123\u2013131 (1990).","journal-title":"Cell"},{"key":"BF348169a0_CR17","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1093\/genetics\/96.1.147","volume":"96","author":"IS Greenwald","year":"1980","unstructured":"Greenwald, I. S. & Horvitz, H. R. Genetics 96, 147\u2013164 (1980).","journal-title":"Genetics"},{"key":"BF348169a0_CR18","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1093\/genetics\/116.3.377","volume":"116","author":"RK Herman","year":"1987","unstructured":"Herman, R. K. Genetics 116, 377\u2013388 (1987).","journal-title":"Genetics"},{"key":"BF348169a0_CR19","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1016\/0012-1606(85)90443-9","volume":"111","author":"EM Hedgecock","year":"1985","unstructured":"Hedgecock, E. M., Culotti, J. G., Thomson, J. N. & Perkins, L. A. Devl. Biol. 111, 158\u2013170 (1985).","journal-title":"Devl. Biol."},{"key":"BF348169a0_CR20","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1016\/0012-1606(86)90314-3","volume":"117","author":"LA Perkins","year":"1986","unstructured":"Perkins, L. A., Hedgecock, E. M., Thomson, J. N. & Culotti, J. G. Devl. Biol. 117, 456\u2013487 (1986).","journal-title":"Devl. Biol."},{"key":"BF348169a0_CR21","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1093\/genetics\/113.1.63","volume":"113","author":"IS Greenwald","year":"1986","unstructured":"Greenwald, I. S. & Horvitz, H. R. Genetics 113, 63\u201372 (1986).","journal-title":"Genetics"},{"key":"BF348169a0_CR22","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1093\/genetics\/124.1.91","volume":"124","author":"AM Villeneuve","year":"1990","unstructured":"Villeneuve, A. M. & Meyer, B. J. Genetics 124, 91\u2013114 (1990).","journal-title":"Genetics"},{"key":"BF348169a0_CR23","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1002\/cne.901980305","volume":"198","author":"P Albert","year":"1981","unstructured":"Albert, P., Brown, S. & Riddle, D. J. comp. Neurol. 198, 436\u2013451 (1981).","journal-title":"J. comp. Neurol."},{"key":"BF348169a0_CR24","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1016\/0092-8674(86)90668-9","volume":"46","author":"C Kenyon","year":"1986","unstructured":"Kenyon, C. Cell 46, 477\u2013487 (1986).","journal-title":"Cell"}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/348169a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/348169a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/348169a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T01:37:06Z","timestamp":1684287426000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/348169a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,11]]},"references-count":24,"journal-issue":{"issue":"6297","published-print":{"date-parts":[[1990,11]]}},"alternative-id":["BF348169a0"],"URL":"https:\/\/doi.org\/10.1038\/348169a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,11]]}}}