{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T19:05:28Z","timestamp":1775243128063,"version":"3.50.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"6387","license":[{"start":{"date-parts":[[1992,8,13]],"date-time":"1992-08-13T00:00:00Z","timestamp":713664000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1992,8,13]],"date-time":"1992-08-13T00:00:00Z","timestamp":713664000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1992,8,13]],"date-time":"1992-08-13T00:00:00Z","timestamp":713664000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[1992,8,13]],"date-time":"1992-08-13T00:00:00Z","timestamp":713664000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1992,8,13]]},"DOI":"10.1038\/358591a0","type":"journal-article","created":{"date-parts":[[2003,6,12]],"date-time":"2003-06-12T23:32:26Z","timestamp":1055460746000},"page":"591-593","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1057,"title":["The catalase\u2014peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis"],"prefix":"10.1038","volume":"358","author":[{"given":"Ying","family":"Zhang","sequence":"first","affiliation":[]},{"given":"Beate","family":"Heym","sequence":"additional","affiliation":[]},{"given":"Bryan","family":"Allen","sequence":"additional","affiliation":[]},{"given":"Douglas","family":"Young","sequence":"additional","affiliation":[]},{"given":"Stewart","family":"Cole","sequence":"additional","affiliation":[]}],"member":"297","reference":[{"key":"BF358591a0_CR1","first-page":"6","volume":"65","author":"CJL Murray","year":"1990","unstructured":"Murray, C. J. L., Styblo, K. & Rouillon, A. Bull. Int. Union against Tuberculosis and Lung Disorders 65, 6\u201324 (1990).","journal-title":"Bull. Int. Union against Tuberculosis and Lung Disorders"},{"key":"BF358591a0_CR2","doi-asserted-by":"publisher","first-page":"750","DOI":"10.1164\/ajrccm\/144.4.750","volume":"144","author":"JH Perriens","year":"1991","unstructured":"Perriens, J. H. et al. Am. Rev. respir. Dis. 144, 750\u2013755 (1991).","journal-title":"Am. Rev. respir. Dis."},{"key":"BF358591a0_CR3","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1056\/NEJM199203053261011","volume":"326","author":"DE Snider","year":"1992","unstructured":"Snider, D. E. & Roper, W. L. New Engl. J. Med. 326, 703\u2013705 (1992).","journal-title":"New Engl. J. Med."},{"key":"BF358591a0_CR4","first-page":"641","volume":"70","author":"ML Cohn","year":"1954","unstructured":"Cohn, M. L., Kovitz, C., Oda, U. & Middlebrook, G. Am. Rev. Tuberc. 70, 641\u2013664 (1954).","journal-title":"Am. Rev. Tuberc."},{"key":"BF358591a0_CR5","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1164\/art.1954.70.6.1102","volume":"70","author":"G Middlebrook","year":"1954","unstructured":"Middlebrook, G., Cohn, M. L. & Scheffer, W. B. Am. Rev. Tuberc. 70, 852\u2013872 (1954).","journal-title":"Am. Rev. Tuberc."},{"key":"BF358591a0_CR6","first-page":"729","volume":"99","author":"J Youatt","year":"1969","unstructured":"Youatt, J. Am. Rev. respir. Dis. 99, 729\u2013749 (1969).","journal-title":"Am. Rev. respir. Dis."},{"key":"BF358591a0_CR7","first-page":"353","volume-title":"The Biology of the Mycobacteria","author":"FG Winder","year":"1982","unstructured":"Winder, F. G. in The Biology of the Mycobacteria Vol. 1 (eds Ratledge, C. & Stanford, J.) 353\u2013438 (Academic, London, 1982)."},{"key":"BF358591a0_CR8","doi-asserted-by":"publisher","first-page":"6987","DOI":"10.1073\/pnas.85.18.6987","volume":"85","author":"SB Snapper","year":"1988","unstructured":"Snapper, S. B. et al. Proc. natn. Acad. Sci. U.S.A. 85, 6987\u20136991 (1988).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF358591a0_CR9","doi-asserted-by":"publisher","first-page":"1911","DOI":"10.1111\/j.1365-2958.1990.tb02040.x","volume":"4","author":"SB Snapper","year":"1990","unstructured":"Snapper, S. B., Melton, R. E., Mustafa, S., Kieser, T. & Jacobs, W. R. Molec. Microbiol. 4, 1911\u20131919 (1990).","journal-title":"Molec. Microbiol."},{"key":"BF358591a0_CR10","unstructured":"Heym, B. & Cole, S. T. Res. Microbiol. (in the press)."},{"key":"BF358591a0_CR11","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1042\/bj1490187","volume":"149","author":"B Gayathri Devi","year":"1975","unstructured":"Gayathri Devi, B., Shaila, M. S., Ramakrishnan, T. & Gopinathan, K. P. Biochem. J. 149, 187\u2013197 (1975).","journal-title":"Biochem. J."},{"key":"BF358591a0_CR12","doi-asserted-by":"publisher","first-page":"4415","DOI":"10.1128\/jb.170.9.4415-4419.1988","volume":"170","author":"BL Triggs-Raine","year":"1988","unstructured":"Triggs-Raine, B. L., Doble, B. W., Mulvey, M. R., Sorby, P. A. & Loewen, P. C. J. Bact. 170, 4415\u20134419 (1988).","journal-title":"J. Bact."},{"key":"BF358591a0_CR13","doi-asserted-by":"publisher","first-page":"4871","DOI":"10.1128\/jb.171.9.4871-4875.1989","volume":"171","author":"S Loprasert","year":"1989","unstructured":"Loprasert, S., Negoro, S. & Okada, H. J. Bact. 171, 4871\u20134875 (1989).","journal-title":"J. Bact."},{"key":"BF358591a0_CR14","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/0378-1119(88)90498-2","volume":"73","author":"MR Mulvey","year":"1988","unstructured":"Mulvey, M. R., Sorby, P. A., Triggs-Raine, B. L. & Loewen, P. C. Gene 73, 337\u2013345 (1988).","journal-title":"Gene"},{"key":"BF358591a0_CR15","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1128\/iai.60.6.2160-2165.1992","volume":"60","author":"Y Zhang","year":"1992","unstructured":"Zhang, Y. et al. Infect. Immun. 60, 2160\u20132165 (1992).","journal-title":"Infect. Immun."},{"key":"BF358591a0_CR16","doi-asserted-by":"publisher","first-page":"1035","DOI":"10.1128\/AAC.35.6.1035","volume":"35","author":"A Quemard","year":"1991","unstructured":"Quemard, A., Lacave, C. & Laneelle, G. Antimicr. Ag. Chemother. 35, 1035\u20131039 (1991).","journal-title":"Antimicr. Ag. Chemother."},{"key":"BF358591a0_CR17","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1128\/AAC.27.3.404","volume":"27","author":"HA Shoeb","year":"1985","unstructured":"Shoeb, H. A., Bowman, B. U., Ottolenghi, A. O. & Merola, A. J. Antimicr. Ag. Chemother. 27, 404\u2013407 (1985).","journal-title":"Antimicr. Ag. Chemother."},{"key":"BF358591a0_CR18","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1111\/j.1365-2958.1991.tb02120.x","volume":"5","author":"Y Zhang","year":"1991","unstructured":"Zhang, Y., Lathigra, R., Garbe, T., Catty, D. & Young, D. Molec. Microbiol. 5, 381\u2013391 (1991).","journal-title":"Molec. Microbiol."},{"key":"BF358591a0_CR19","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/0003-2697(86)90200-9","volume":"157","author":"LG Wayne","year":"1986","unstructured":"Wayne, L. G. & Diaz, G. A. Analyt. Biochem. 157, 89\u201392 (1986).","journal-title":"Analyt. Biochem."},{"key":"BF358591a0_CR20","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1099\/00221287-104-1-37","volume":"104","author":"PS Jackett","year":"1978","unstructured":"Jackett, P. S., Aber, V. & Lowrie, D. J. gen. Microbiol. 104, 37\u201345 (1978).","journal-title":"J. gen. Microbiol."},{"key":"BF358591a0_CR21","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1002\/path.1700860213","volume":"86","author":"DA Mitchison","year":"1963","unstructured":"Mitchison, D. A., Selkon, J. B. & Lloyd, J. J. Path. Bact. 86, 377\u2013386 (1963).","journal-title":"J. Path. Bact."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/358591a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/358591a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/358591a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T11:14:10Z","timestamp":1744283650000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/358591a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,8,13]]},"references-count":21,"journal-issue":{"issue":"6387","published-print":{"date-parts":[[1992,8,13]]}},"alternative-id":["BF358591a0"],"URL":"https:\/\/doi.org\/10.1038\/358591a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,8,13]]},"assertion":[{"value":"13 May 1992","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 July 1992","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}