{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T06:18:48Z","timestamp":1767853128943,"version":"3.49.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"6392","license":[{"start":{"date-parts":[[1992,9,1]],"date-time":"1992-09-01T00:00:00Z","timestamp":715305600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1992,9]]},"DOI":"10.1038\/359237a0","type":"journal-article","created":{"date-parts":[[2003,6,12]],"date-time":"2003-06-12T23:33:39Z","timestamp":1055460819000},"page":"237-241","source":"Crossref","is-referenced-by-count":185,"title":["Evidence that Hensen's node is a site of retinoic acid synthesis"],"prefix":"10.1038","volume":"359","author":[{"given":"Brigid L. M.","family":"Hogan","sequence":"first","affiliation":[]},{"given":"Christina","family":"Thaller","sequence":"additional","affiliation":[]},{"given":"Gregor","family":"Eichele","sequence":"additional","affiliation":[]}],"member":"297","reference":[{"key":"BF359237a0_CR1","volume-title":"The Epigenetics of Birds","author":"CH Waddington","year":"1952","unstructured":"Waddington, C. H. The Epigenetics of Birds (Cambridge Univ. Press, Cambridge, 1952)."},{"key":"BF359237a0_CR2","first-page":"257","volume":"94","author":"A Hornbruch","year":"1986","unstructured":"Hornbruch, A. & Wolpert, L. J. Embryol. exp. Morph. 94, 257\u2013265 (1986).","journal-title":"J. Embryol. exp. Morph."},{"key":"BF359237a0_CR3","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1038\/345819a0","volume":"345","author":"M Wagner","year":"1990","unstructured":"Wagner, M., Thaller, C. Jessell, T. & Eichele, G. Nature 345, 819\u2013822 (1990).","journal-title":"Nature"},{"key":"BF359237a0_CR4","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1038\/296564a0","volume":"296","author":"C Tickle","year":"1982","unstructured":"Tickle, C. et al. Nature 296, 564\u2013566 (1982).","journal-title":"Nature"},{"key":"BF359237a0_CR5","first-page":"269","volume":"78","author":"D Summerbell","year":"1983","unstructured":"Summerbell, D. J. Embryol. exp. Morph. 78, 269\u2013289 (1983).","journal-title":"J. Embryol. exp. Morph."},{"key":"BF359237a0_CR6","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1016\/0168-9525(89)90096-6","volume":"5","author":"G Eichele","year":"1989","unstructured":"Eichele, G. Trends Genet. 5, 246\u2013251 (1989).","journal-title":"Trends Genet."},{"key":"BF359237a0_CR7","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1038\/345815a0","volume":"345","author":"C Thaller","year":"1990","unstructured":"Thaller, C. & Eichele, G. Nature 345, 815\u2013819 (1990).","journal-title":"Nature"},{"key":"BF359237a0_CR8","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1242\/dev.103.3.473","volume":"103","author":"C Thaller","year":"1988","unstructured":"Thaller, C. & Eichele, G. Development 103, 473\u2013483 (1988).","journal-title":"Development"},{"key":"BF359237a0_CR9","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1242\/dev.111.1.45","volume":"111","author":"E Ruberte","year":"1991","unstructured":"Ruberte, E., Doll\u00e9, P., Chambon, P. & Morriss-Kay, G. Development 111, 45\u201360 (1991).","journal-title":"Development"},{"key":"BF359237a0_CR10","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1242\/dev.111.1.245","volume":"111","author":"SM Smith","year":"1991","unstructured":"Smith, S. M. & Eichele, G. Development 111, 245\u2013252 (1991).","journal-title":"Development"},{"key":"BF359237a0_CR11","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1101\/gad.5.8.1333","volume":"5","author":"J Rossant","year":"1991","unstructured":"Rossant, J. et al. Genes Dev. 5, 1333\u20131344 (1991).","journal-title":"Genes Dev."},{"key":"BF359237a0_CR12","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1038\/340140a0","volume":"340","author":"AJ Durston","year":"1989","unstructured":"Durston, A. J. et al. Nature 340, 140\u2013144 (1989).","journal-title":"Nature"},{"key":"BF359237a0_CR13","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1101\/gad.4.6.932","volume":"4","author":"HL Sive","year":"1990","unstructured":"Sive, H. L., Draper, B. W., Harland, R. M. & Weintraub, H. Genes Dev. 4, 932\u2013942 (1990).","journal-title":"Genes Dev."},{"key":"BF359237a0_CR14","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1101\/gad.5.2.175","volume":"5","author":"A Ruiz i Altaba","year":"1991","unstructured":"Ruiz i Altaba, A. & Jessell, T. Genes Dev. 5, 175\u2013187 (1991).","journal-title":"Genes Dev."},{"key":"BF359237a0_CR15","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/0896-6273(91)90262-X","volume":"7","author":"CR Sharpe","year":"1991","unstructured":"Sharpe, C. R. Neuron 7, 239\u2013247 (1991).","journal-title":"Neuron"},{"key":"BF359237a0_CR16","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/0092-8674(91)90574-I","volume":"67","author":"M Kessel","year":"1991","unstructured":"Kessel, M. & Gruss, P. Cell 67, 89\u2013104 (1991).","journal-title":"Cell"},{"key":"BF359237a0_CR17","doi-asserted-by":"publisher","first-page":"2985","DOI":"10.1002\/j.1460-2075.1991.tb07849.x","volume":"10","author":"GM Morriss-Kay","year":"1991","unstructured":"Morriss-Kay, G. M., Murphy, P., Hill, R. E. & Davidson, D. R. EMBO J. 10, 2985\u20132995 (1991).","journal-title":"EMBO J."},{"key":"BF359237a0_CR18","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1242\/dev.114.4.841","volume":"114","author":"OH Sundin","year":"1992","unstructured":"Sundin, O. H. & Eichele, G. Development 114, 841\u2013852 (1992).","journal-title":"Development"},{"key":"BF359237a0_CR19","unstructured":"Conlon, R. A. & Rossant, J. Development (in the press)."},{"key":"BF359237a0_CR20","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1242\/dev.112.2.615","volume":"112","author":"MAJ Selleck","year":"1991","unstructured":"Selleck, M. A. J. & Stern, C. D. Development 112, 615\u2013626 (1991).","journal-title":"Development"},{"key":"BF359237a0_CR21","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1002\/aja.1001930304","volume":"193","author":"GC Schoenwolf","year":"1992","unstructured":"Schoenwolf, G. C., Garcia-Martinez, V. & Dias, M. S. Dev. Dynamics 193, 235\u2013248 (1992).","journal-title":"Dev. Dynamics"},{"key":"BF359237a0_CR22","first-page":"3","volume-title":"Post Implantation Development in the Mouse, Ciba Foundation Symp.","author":"KA Lawson","year":"1992","unstructured":"Lawson, K. A. & Pedersen, R. A. in Post Implantation Development in the Mouse, Ciba Foundation Symp. 165 (eds Chadwick D. J. & Marsh, J.) 3\u201326 (Wiley, Chichester, 1992)."},{"key":"BF359237a0_CR23","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1007\/BF00299630","volume":"156","author":"CD Stern","year":"1979","unstructured":"Stern, C. D. Anat. Embryol. 156, 319\u2013329 (1979).","journal-title":"Anat. Embryol."},{"key":"BF359237a0_CR24","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1038\/346763a0","volume":"346","author":"A Simeone","year":"1990","unstructured":"Simeone, A. et al. Nature 346, 763\u2013766 (1990).","journal-title":"Nature"},{"key":"BF359237a0_CR25","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/0925-4773(91)90029-6","volume":"33","author":"A Simeone","year":"1991","unstructured":"Simeone, A. et al. Mech. Dev. 33, 215\u2013228 (1991).","journal-title":"Mech. Dev."},{"key":"BF359237a0_CR26","doi-asserted-by":"publisher","first-page":"5497","DOI":"10.1093\/nar\/19.20.5497","volume":"19","author":"N Papalopulu","year":"1991","unstructured":"Papalopulu, N., Lovell-Badge, R. & Krumlauf, R. Nucleic Acids Res. 19, 5497\u20135506 (1991).","journal-title":"Nucleic Acids Res."},{"key":"BF359237a0_CR27","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1242\/dev.111.1.61","volume":"111","author":"P Murphy","year":"1991","unstructured":"Murphy, P. & Hill, R. E. Development 111, 61\u201374 (1991).","journal-title":"Development"},{"key":"BF359237a0_CR28","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/0092-8674(92)90471-N","volume":"68","author":"W McGinnis","year":"1992","unstructured":"McGinnis W. & Krumlauf, R. Cell 68, 283\u2013302 (1992).","journal-title":"Cell"},{"key":"BF359237a0_CR29","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/0092-8674(92)90469-S","volume":"68","author":"TM Jessell","year":"1992","unstructured":"Jessell, T. M. & Melton, D. A. Cell 68, 257\u2013270 (1992).","journal-title":"Cell"},{"key":"BF359237a0_CR30","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1038\/254199a0","volume":"254","author":"C Tickle","year":"1975","unstructured":"Tickle, C., Summerbell, D. & Wolpert, L. Nature 254, 199\u2013202 (1975).","journal-title":"Nature"},{"key":"BF359237a0_CR31","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/0165-3806(81)90026-2","volume":"2","author":"HJ Romijn","year":"1982","unstructured":"Romijn, H. J. et al. Devl Brain Res. 2, 583\u2013589 (1982).","journal-title":"Devl Brain Res."},{"key":"BF359237a0_CR32","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/0003-2697(80)90165-7","volume":"102","author":"C Labarca","year":"1980","unstructured":"Labarca, C. & Paigen, K. Analyt. Biochem. 102, 344\u2013352 (1980).","journal-title":"Analyt. Biochem."},{"key":"BF359237a0_CR33","first-page":"208","volume":"6","author":"SJ Gaunt","year":"1990","unstructured":"Gaunt, S. J. & Singh P. B. Trends Genet. 6, 208\u2013212 (1990).","journal-title":"Trends Genet."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/359237a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/359237a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/359237a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T02:17:17Z","timestamp":1684289837000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/359237a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,9]]},"references-count":33,"journal-issue":{"issue":"6392","published-print":{"date-parts":[[1992,9]]}},"alternative-id":["BF359237a0"],"URL":"https:\/\/doi.org\/10.1038\/359237a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,9]]}}}