{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T17:22:51Z","timestamp":1791912171144,"version":"4.3.4"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"6982","license":[{"start":{"date-parts":[[2004,4,1]],"date-time":"2004-04-01T00:00:00Z","timestamp":1080777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2004,4,1]],"date-time":"2004-04-01T00:00:00Z","timestamp":1080777600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[2004,4,1]]},"DOI":"10.1038\/428486a","type":"journal-article","created":{"date-parts":[[2004,4,1]],"date-time":"2004-04-01T09:06:43Z","timestamp":1080810403000},"page":"486-486","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1496,"title":["A marker for Stevens\u2013Johnson syndrome"],"prefix":"10.1038","volume":"428","author":[{"given":"Wen-Hung","family":"Chung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuen-Iu","family":"Hung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Shang","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mo-Song","family":"Hsih","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Cheng","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsin-Chun","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jer-Yuarn","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-Tsong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2004,4,1]]},"reference":[{"issue":"suppl.","key":"BF428486a_CR1","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1111\/1523-1747.ep12388434","volume":"102","author":"J-C Roujeau","year":"1994","unstructured":"Roujeau, J.-C. J. Invest. Dermatol. 102 (suppl.), 28\u201330 (1994).","journal-title":"J. Invest. Dermatol."},{"key":"BF428486a_CR2","doi-asserted-by":"publisher","first-page":"1600","DOI":"10.1056\/NEJM199512143332404","volume":"333","author":"J-C Roujeau","year":"1995","unstructured":"Roujeau, J.-C. et al. N. Engl. J. Med. 333, 1600\u20131607 (1995).","journal-title":"N. Engl. J. Med."},{"key":"BF428486a_CR3","doi-asserted-by":"publisher","first-page":"2190","DOI":"10.1016\/S0140-6736(98)05418-X","volume":"353","author":"B Rzany","year":"1999","unstructured":"Rzany, B. et al. Lancet 353, 2190\u20132194 (1999).","journal-title":"Lancet"},{"key":"BF428486a_CR4","first-page":"357","volume":"53","author":"CK Svensson","year":"2001","unstructured":"Svensson, C. K., Cowen, E. W. & Gaspari, A. A. Pharmacol. Rev. 53, 357\u2013379 (2001).","journal-title":"Pharmacol. Rev."},{"key":"BF428486a_CR5","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1038\/nrg1229","volume":"4","author":"DB Goldstein","year":"2003","unstructured":"Goldstein, D. B., Tate, S. K. & Sisodiya, S. M. Nature Rev. Genet. 4, 937\u2013947 (2003).","journal-title":"Nature Rev. Genet."},{"key":"BF428486a_CR6","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1111\/j.1399-0039.1986.tb00491.x","volume":"28","author":"J-C Roujeau","year":"1986","unstructured":"Roujeau, J. -C. et al. Tissue Antigens 28, 251\u2013254 (1986).","journal-title":"Tissue Antigens"},{"key":"BF428486a_CR7","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/S1074-7613(01)00115-7","volume":"14","author":"HA Erlich","year":"2001","unstructured":"Erlich, H. A., Opelz, G. & Hansen, J. Immunity 14, 347\u2013356 (2001).","journal-title":"Immunity"},{"key":"BF428486a_CR8","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/0305-4179(95)00140-9","volume":"22","author":"AKM Khoo","year":"1996","unstructured":"Khoo, A. K. M. & Foo, C. L. Burns 22, 275\u2013278 (1996).","journal-title":"Burns"},{"key":"BF428486a_CR9","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1046\/j.1365-4362.1998.00490.x","volume":"37","author":"MD Kamaliah","year":"1998","unstructured":"Kamaliah, M. D., Zainal, D., Mokhtar, N. & Nazmi, N. Int. J. Dermatol. 37, 520\u2013523 (1998).","journal-title":"Int. J. Dermatol."},{"key":"BF428486a_CR10","first-page":"327","volume-title":"HLA 1998","author":"L Geer","year":"1998","unstructured":"Geer, L., Terasaki, P. I. & Gjertson, D. W. in HLA 1998 (eds Gjertson, D. W. & Terasaki, P. I.) 327\u2013363 (Am. Soc. Histocompat. Immunogenet., Kansas, 1998)."},{"key":"BF428486a_CR11","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1056\/NEJM197304052881403","volume":"288","author":"Schlosstein","year":"1973","unstructured":"Schlosstein, L., Terasaki, P. I., Bluestone, R. & Pearson, C. M. N. Engl. J. Med. 288, 704\u2013706 (1973).","journal-title":"N. Engl. J. Med."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/428486a.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/428486a","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/428486a.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T21:03:45Z","timestamp":1704920625000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/428486a"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,4,1]]},"references-count":11,"journal-issue":{"issue":"6982","published-print":{"date-parts":[[2004,4,1]]}},"alternative-id":["BF428486a"],"URL":"https:\/\/doi.org\/10.1038\/428486a","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,4,1]]},"assertion":[{"value":"1 April 2004","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing financial interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}