{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T03:59:27Z","timestamp":1791172767416,"version":"4.1.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[1999,10,27]],"date-time":"1999-10-27T00:00:00Z","timestamp":940982400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Cell Biol"],"published-print":{"date-parts":[[1999,12]]},"DOI":"10.1038\/70249","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T08:47:57Z","timestamp":1027673277000},"page":"467-471","source":"Crossref","is-referenced-by-count":54,"title":["Coordination of calcium signalling by endothelial-derived nitric oxide in the intact liver"],"prefix":"10.1038","volume":"1","author":[{"given":"Sandip","family":"Patel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence D.","family":"Robb-Gaspers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerri Anne","family":"Stellato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mimi","family":"Shon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew P.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[1999,10,27]]},"reference":[{"key":"BFncb1299_467_CR1","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1038\/361315a0","volume":"361","author":"MJ Berridge","year":"1993","unstructured":"Berridge, M. J. Inositol trisphosphate and calcium signalling. Nature 361, 315\u2013325 (1993).","journal-title":"Nature"},{"key":"BFncb1299_467_CR2","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1007\/BF00237369","volume":"145","author":"CW Taylor","year":"1995","unstructured":"Taylor, C. W. & Traynor, D. Calcium and inositol trisphosphate receptors. J. Membr. Biol. 145, 109\u2013118 (1995).","journal-title":"J. Membr. Biol."},{"key":"BFncb1299_467_CR3","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1054\/ceca.1999.0021","volume":"25","author":"S Patel","year":"1999","unstructured":"Patel, S., Joseph, S. K. & Thomas, A. P. Molecular properties of inositol 1,4,5-trisphosphate receptors. Cell Calcium 25, 247\u2013264 (1999).","journal-title":"Cell Calcium"},{"key":"BFncb1299_467_CR4","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/0092-8674(95)90430-1","volume":"82","author":"G Hajn\u00f3czky","year":"1995","unstructured":"Hajn\u00f3czky, G., Robb-Gaspers, L. D., Seitz, M. B. & Thomas, A. P. Decoding of cytosolic calcium oscillations in the mitochondria. Cell 82, 415\u2013424 (1995).","journal-title":"Cell"},{"key":"BFncb1299_467_CR5","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1038\/375784a0","volume":"375","author":"X Gu","year":"1995","unstructured":"Gu, X. & Spitzer, N. C. Distinct aspects of neuronal differentiation encoded by frequency of spontaneous Ca2+ transients. Nature 375, 784\u2013787 (1995).","journal-title":"Nature"},{"key":"BFncb1299_467_CR6","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1038\/31960","volume":"392","author":"RE Dolmetsch","year":"1998","unstructured":"Dolmetsch, R. E., Xu, K. & Lewis, R. S. Calcium oscillations increase the efficiency and specificity of gene expression. Nature 392, 933\u2013936 (1998).","journal-title":"Nature"},{"key":"BFncb1299_467_CR7","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1038\/31965","volume":"392","author":"W-H Li","year":"1998","unstructured":"Li, W.-H., llopis, J., Whitney, M., Zlokarnik, G. & Tsien, R. Y. Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression. Nature 392, 936\u2013941 (1998).","journal-title":"Nature"},{"key":"BFncb1299_467_CR8","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1242\/jeb.200.2.315","volume":"200","author":"MJ Berridge","year":"1997","unstructured":"Berridge, M. J. Elementary and global aspects of calcium signalling. J. Exp. Biol. 200, 315\u2013319 (1997).","journal-title":"J. Exp. Biol."},{"key":"BFncb1299_467_CR9","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.1096\/fasebj.10.13.8940296","volume":"10","author":"AP Thomas","year":"1996","unstructured":"Thomas, A. P., Bird, G. St J., Hajn\u00f3czky, G., Robb-Gaspers, L. D. & Putney, J. W. Jr Spatial and temporal aspects of cellular calcium signaling. FASEB J. 10, 1505\u20131517 (1996).","journal-title":"FASEB J."},{"key":"BFncb1299_467_CR10","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/0303-7207(94)90136-8","volume":"98","author":"MJ Sanderson","year":"1994","unstructured":"Sanderson, M. J., Charles, A. C., Boitano, S. & Dirksen, E. R. Mechanisms and function of intercellular calcium signaling. Mol. Cell. Endocrinol. 98, 173\u2013187 (1994).","journal-title":"Mol. Cell. Endocrinol."},{"key":"BFncb1299_467_CR11","first-page":"109","volume":"43","author":"S Moncada","year":"1991","unstructured":"Moncada, S., Palmer, R. M. J. & Higgs, E. A. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43, 109\u2013142 (1991).","journal-title":"Pharmacol. Rev."},{"key":"BFncb1299_467_CR12","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1146\/annurev.bi.63.070194.001135","volume":"63","author":"DS Bredt","year":"1994","unstructured":"Bredt, D. S. & Snyder, S. H. Nitric oxide: a physiologic messenger molecule. Annu. Rev. Biochem. 63, 175\u2013195 (1994).","journal-title":"Annu. Rev. Biochem."},{"key":"BFncb1299_467_CR13","doi-asserted-by":"publisher","first-page":"8102","DOI":"10.1074\/jbc.270.14.8102","volume":"270","author":"LD Robb-Gaspers","year":"1995","unstructured":"Robb-Gaspers, L. D. & Thomas, A. P. Coordination of Ca2+ signaling by intercellular propagation of Ca2+ waves in the intact liver. J. Biol. Chem. 270, 8102\u20138107 (1995).","journal-title":"J. Biol. Chem."},{"key":"BFncb1299_467_CR14","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1038\/281384a0","volume":"281","author":"JD Pearson","year":"1979","unstructured":"Pearson, J. D. & Gordon, J. L. Vascular endothelial and smooth muscle cells in culture selectively release adenine nucleotides. Nature 281, 384\u2013386 (1979).","journal-title":"Nature"},{"key":"BFncb1299_467_CR15","first-page":"13","volume":"4","author":"V Ralevic","year":"1998","unstructured":"Ralevic, V. & Burnstock, G. Receptors for purines and pyrimidines. Pharmacol. Rev. 4, 13\u201392 (1998).","journal-title":"Pharmacol. Rev"},{"key":"BFncb1299_467_CR16","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1042\/bj2690499","volume":"269","author":"CJ Dixon","year":"1990","unstructured":"Dixon, C. J., Woods, N. M., Cuthbertson, K. S. R. & Cobbold, P. H. Evidence for two Ca2+-mobilizing purinoreceptors on rat hepatocytes. Biochem. J. 269, 499\u2013502 (1990).","journal-title":"Biochem. J."},{"key":"BFncb1299_467_CR17","doi-asserted-by":"publisher","first-page":"19817","DOI":"10.1074\/jbc.271.33.19817","volume":"271","author":"TA Rooney","year":"1996","unstructured":"Rooney, T. A., Joseph, S. K., Queen, C. & Thomas, A. P. Cyclic GMP induces oscillatory calcium signals in rat hepatocytes. J. Biol. Chem. 271, 19817\u201319825 (1996).","journal-title":"J. Biol. Chem."},{"key":"BFncb1299_467_CR18","doi-asserted-by":"crossref","unstructured":"Guihard, G., Combettes, L. & Capiod, T. 3\":5\"-cyclic guanosine monophosphate (cGMP) potentiates the inositol 1,4,5-trisphosphate-evoked Ca2+ release in guinea-pig hepatocytes. Biochem. J. 318, 849\u2013855 (1996).","DOI":"10.1042\/bj3180849"},{"key":"BFncb1299_467_CR19","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1021\/bi00054a013","volume":"32","author":"T Akaike","year":"1993","unstructured":"Akaike, T. et al. Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor\/.NO through a radical reaction. Biochemistry 32, 827\u2013832 (1993).","journal-title":"Biochemistry"},{"key":"BFncb1299_467_CR20","doi-asserted-by":"publisher","first-page":"4987","DOI":"10.1093\/emboj\/17.17.4987","volume":"17","author":"LD Robb-Gaspers","year":"1998","unstructured":"Robb-Gaspers, L. D. et al. Integrating cytosolic calcium signals into mitochondrial metabolic responses. EMBO J. 17, 4987\u20135000 (1998).","journal-title":"EMBO J."},{"key":"BFncb1299_467_CR21","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1126\/science.279.5348.227","volume":"279","author":"P De Koninck","year":"1998","unstructured":"De Koninck, P. & Schulman, H. Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations. Science 279, 191\u2013192 (1998).","journal-title":"Science"},{"key":"BFncb1299_467_CR22","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/S0092-8674(00)81763-8","volume":"95","author":"E Oancea","year":"1998","unstructured":"Oancea, E. & Meyer, T. Protein kinase C as a molecular machine for decoding calcium and diacyl glycerol signals. Cell 95, 307\u2013318 (1998).","journal-title":"Cell"},{"key":"BFncb1299_467_CR23","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1002\/(SICI)1098-1136(199812)24:4<398::AID-GLIA5>3.0.CO;2-R","volume":"24","author":"L Leybaert","year":"1998","unstructured":"Leybaert, L., Paemeleire, K., Strahonja, A. & Sanderson, M. J. Inositol-trisphosphate-dependent intercellular calcium signaling in and between astrocytes and endothelial cells. Glia 24, 398\u2013407 (1998).","journal-title":"Glia"},{"key":"BFncb1299_467_CR24","doi-asserted-by":"publisher","first-page":"3121","DOI":"10.1074\/jbc.273.6.3121","volume":"273","author":"S Patel","year":"1998","unstructured":"Patel, S., Santra, M., McQuillan, D. J., Iozzo, R. V. & Thomas, A. P. Decorin activates the epidermal growth factor receptor and elevates cytosolic Ca2+ in A431 carcinoma cells. J. Biol. Chem. 273, 3121\u20133124 (1998).","journal-title":"J. Biol. Chem."},{"key":"BFncb1299_467_CR25","first-page":"93","volume":"114","author":"AJ Morgan","year":"1999","unstructured":"Morgan, A. J. & Thomas, A. P. Single cell and subcellular measurement of intracellular Ca2+ concentration ([Ca2+]i). Methods Mol. Biol. 114, 93\u2013123 (1999).","journal-title":"Methods Mol. Biol."}],"container-title":["Nature Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/ncb1299_467","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ncb1299_467.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ncb1299_467.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T19:27:03Z","timestamp":1684438023000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ncb1299_467"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,10,27]]},"references-count":25,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1999,12]]}},"alternative-id":["BFncb1299_467"],"URL":"https:\/\/doi.org\/10.1038\/70249","relation":{},"ISSN":["1465-7392","1476-4679"],"issn-type":[{"value":"1465-7392","type":"print"},{"value":"1476-4679","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,10,27]]}}}