{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T17:53:32Z","timestamp":1775757212568,"version":"3.50.1"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"7484","license":[{"start":{"date-parts":[[2013,12,18]],"date-time":"2013-12-18T00:00:00Z","timestamp":1387324800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/"},{"start":{"date-parts":[[2013,12,18]],"date-time":"2013-12-18T00:00:00Z","timestamp":1387324800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[2014,1,23]]},"DOI":"10.1038\/nature12817","type":"journal-article","created":{"date-parts":[[2013,12,18]],"date-time":"2013-12-18T10:05:56Z","timestamp":1387361156000},"page":"546-549","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":602,"title":["The genome of the recently domesticated crop plant sugar beet (Beta vulgaris)"],"prefix":"10.1038","volume":"505","author":[{"given":"Juliane C.","family":"Dohm","sequence":"first","affiliation":[]},{"given":"Andr\u00e9 E.","family":"Minoche","sequence":"additional","affiliation":[]},{"given":"Daniela","family":"Holtgr\u00e4we","sequence":"additional","affiliation":[]},{"given":"Salvador","family":"Capella-Guti\u00e9rrez","sequence":"additional","affiliation":[]},{"given":"Falk","family":"Zakrzewski","sequence":"additional","affiliation":[]},{"given":"Hakim","family":"Tafer","sequence":"additional","affiliation":[]},{"given":"Oliver","family":"Rupp","sequence":"additional","affiliation":[]},{"given":"Thomas Rosleff","family":"S\u00f6rensen","sequence":"additional","affiliation":[]},{"given":"Ralf","family":"Stracke","sequence":"additional","affiliation":[]},{"given":"Richard","family":"Reinhardt","sequence":"additional","affiliation":[]},{"given":"Alexander","family":"Goesmann","sequence":"additional","affiliation":[]},{"given":"Thomas","family":"Kraft","sequence":"additional","affiliation":[]},{"given":"Britta","family":"Schulz","sequence":"additional","affiliation":[]},{"given":"Peter F.","family":"Stadler","sequence":"additional","affiliation":[]},{"given":"Thomas","family":"Schmidt","sequence":"additional","affiliation":[]},{"given":"Toni","family":"Gabald\u00f3n","sequence":"additional","affiliation":[]},{"given":"Hans","family":"Lehrach","sequence":"additional","affiliation":[]},{"given":"Bernd","family":"Weisshaar","sequence":"additional","affiliation":[]},{"given":"Heinz","family":"Himmelbauer","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2013,12,18]]},"reference":[{"key":"BFnature12817_CR1","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1007\/BF02672069","volume":"9","author":"K Arumuganathan","year":"1991","unstructured":"Arumuganathan, K. & Earle, E. D. Nuclear DNA content of some important plant species. Plant Mol. Biol. Rep. 9, 208\u2013218 (1991)","journal-title":"Plant Mol. Biol. Rep."},{"key":"BFnature12817_CR2","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1111\/j.1365-313X.2011.04898.x","volume":"70","author":"JC Dohm","year":"2012","unstructured":"Dohm, J. C. et al. Palaeohexaploid ancestry for Caryophyllales inferred from extensive gene-based physical and genetic mapping of the sugar beet genome (Beta vulgaris). Plant J. 70, 528\u2013540 (2012)","journal-title":"Plant J."},{"key":"BFnature12817_CR3","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1007\/BF00022414","volume":"41","author":"HE Fischer","year":"1989","unstructured":"Fischer, H. E. Origin of the \u2018Weisse Schlesische R\u00fcbe\u2019 (white Silesian beet) and resynthesis of sugar beet. Euphytica 41, 75\u201380 (1989)","journal-title":"Euphytica"},{"key":"BFnature12817_CR4","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1007\/BF00485947","volume":"12","author":"RB Flavell","year":"1974","unstructured":"Flavell, R. B., Bennett, M. D., Smith, J. B. & Smith, D. B. Genome size and the proportion of repeated nucleotide sequence DNA in plants. Biochem. Genet. 12, 257\u2013269 (1974)","journal-title":"Biochem. Genet."},{"key":"BFnature12817_CR5","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/978-0-387-92765-7_6","volume-title":"Root Tuber Crops","author":"E Biancardi","year":"2010","unstructured":"Biancardi, E., McGrath, J. M., Panella, L., Lewellen, R. & Stevanato, P. in Root Tuber Crops Vol. 7 (ed. Bradshaw, J. E. ) 173\u2013219 (Springer, 2010)"},{"key":"BFnature12817_CR6","unstructured":"Stevens, P. Angiosperm Phylogeny Website (2012) http:\/\/www.mobot.org\/MOBOT\/research\/APweb\/"},{"key":"BFnature12817_CR7","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1111\/j.1365-313X.2012.05102.x","volume":"72","author":"S Paesold","year":"2012","unstructured":"Paesold, S., Borchardt, D., Schmidt, T. & Dechyeva, D. A sugar beet (Beta vulgaris L.) reference FISH karyotype for chromosome and chromosome-arm identification, integration of genetic linkage groups and analysis of major repeat family distribution. Plant J. 72, 600\u2013611 (2012)","journal-title":"Plant J."},{"key":"BFnature12817_CR8","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1111\/j.1365-313X.2008.03665.x","volume":"57","author":"JC Dohm","year":"2009","unstructured":"Dohm, J. C., Lange, C., Reinhardt, R. & Himmelbauer, H. Haplotype divergence in Beta vulgaris and microsynteny with sequenced plant genomes. Plant J. 57, 14\u201326 (2009)","journal-title":"Plant J."},{"key":"BFnature12817_CR9","doi-asserted-by":"publisher","first-page":"R109","DOI":"10.1186\/gb-2007-8-6-r109","volume":"8","author":"J Huerta-Cepas","year":"2007","unstructured":"Huerta-Cepas, J., Dopazo, H., Dopazo, J. & Gabald\u00f3n, T. The human phylome. Genome Biol. 8, R109 (2007)","journal-title":"Genome Biol."},{"key":"BFnature12817_CR10","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1046\/j.1095-8339.2003.t01-1-00158.x","volume":"141","author":"The Angiosperm Phylogeny Group","year":"2003","unstructured":"The Angiosperm Phylogeny Group An update of the Angiosperm Phylogeny Group classification for the orders and families of flowering plants: APG II. Bot. J. Linn. Soc. 141, 399\u2013436 (2003)","journal-title":"Bot. J. Linn. Soc."},{"key":"BFnature12817_CR11","doi-asserted-by":"crossref","unstructured":"Moore, M. J., Soltis, P. S., Bell, C. D., Burleigh, J. G. & Soltis, D. E. Phylogenetic analysis of 83 plastid genes further resolves the early diversification of eudicots. Proc. Natl Acad. Sci. USA (2010)","DOI":"10.1073\/pnas.0907801107"},{"key":"BFnature12817_CR12","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1139\/g02-106","volume":"46","author":"S Hunger","year":"2003","unstructured":"Hunger, S. et al. Isolation and linkage analysis of expressed disease-resistance gene analogues of sugar beet (Beta vulgaris L.). Genome 46, 70\u201382 (2003)","journal-title":"Genome"},{"key":"BFnature12817_CR13","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1007\/s00239-003-2524-4","volume":"58","author":"Y Tian","year":"2004","unstructured":"Tian, Y., Fan, L., Thurau, T., Jung, C. & Cai, D. The absence of TIR-type resistance gene analogues in the sugar beet (Beta vulgaris L.) genome. J. Mol. Evol. 58, 40\u201353 (2004)","journal-title":"J. Mol. Evol."},{"key":"BFnature12817_CR14","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1007\/s00122-007-0591-4","volume":"115","author":"K Schneider","year":"2007","unstructured":"Schneider, K. et al. Analysis of DNA polymorphisms in sugar beet (Beta vulgaris L.) and development of an SNP-based map of expressed genes. Theor. Appl. Genet. 115, 601\u2013615 (2007)","journal-title":"Theor. Appl. Genet."},{"key":"BFnature12817_CR15","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4614-0842-0","volume-title":"Beta maritima: The Origin of Beets","author":"E Biancardi","year":"2012","unstructured":"Biancardi, E., Panella, L. W. & Lewellen, R. T. Beta maritima: The Origin of Beets (Springer, 2012)"},{"key":"BFnature12817_CR16","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1016\/j.cub.2012.04.007","volume":"22","author":"PA Pin","year":"2012","unstructured":"Pin, P. A. et al. The role of a pseudo-response regulator gene in life cycle adaptation and domestication of beet. Curr. Biol. 22, 1095\u20131101 (2012)","journal-title":"Curr. Biol."},{"key":"BFnature12817_CR17","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1146\/annurev-arplant-042110-103827","volume":"64","author":"PS Schnable","year":"2013","unstructured":"Schnable, P. S. & Springer, N. M. Progress toward understanding heterosis in crop plants. Annu. Rev. Plant Biol. 64, 71\u201388 (2013)","journal-title":"Annu. Rev. Plant Biol."},{"key":"BFnature12817_CR18","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1007\/s00438-003-0821-7","volume":"269","author":"U Hohmann","year":"2003","unstructured":"Hohmann, U. et al. A bacterial artificial chromosome (BAC) library of sugar beet and a physical map of the region encompassing the bolting gene B. Mol. Genet. Genomics 269, 126\u2013136 (2003)","journal-title":"Mol. Genet. Genomics"},{"key":"BFnature12817_CR19","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1139\/G08-071","volume":"51","author":"C Lange","year":"2008","unstructured":"Lange, C., Holtgr\u00e4we, D., Schulz, B., Weisshaar, B. & Himmelbauer, H. Construction and characterization of a sugar beet (Beta vulgaris) fosmid library. Genome 51, 948\u2013951 (2008)","journal-title":"Genome"},{"key":"BFnature12817_CR20","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/2047-217X-1-18","volume":"1","author":"R Luo","year":"2012","unstructured":"Luo, R. et al. SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler. Gigascience 1, 18 (2012)","journal-title":"Gigascience"},{"key":"BFnature12817_CR21","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1093\/bioinformatics\/btq683","volume":"27","author":"M Boetzer","year":"2011","unstructured":"Boetzer, M., Henkel, C. V., Jansen, H. J., Butler, D. & Pirovano, W. Scaffolding pre-assembled contigs using SSPACE. Bioinformatics 27, 578\u2013579 (2011)","journal-title":"Bioinformatics"},{"key":"BFnature12817_CR22","doi-asserted-by":"publisher","first-page":"1754","DOI":"10.1093\/bioinformatics\/btp324","volume":"25","author":"H Li","year":"2009","unstructured":"Li, H. & Durbin, R. Fast and accurate short read alignment with Burrows\u2013Wheeler transform. Bioinformatics 25, 1754\u20131760 (2009)","journal-title":"Bioinformatics"},{"key":"BFnature12817_CR23","doi-asserted-by":"publisher","first-page":"2078","DOI":"10.1093\/bioinformatics\/btp352","volume":"25","author":"H Li","year":"2009","unstructured":"Li, H. et al. The Sequence Alignment\/Map format and SAMtools. Bioinformatics 25, 2078\u20132079 (2009)","journal-title":"Bioinformatics"},{"key":"BFnature12817_CR24","doi-asserted-by":"publisher","first-page":"1269","DOI":"10.1101\/gr.88502","volume":"12","author":"Z Bao","year":"2002","unstructured":"Bao, Z. & Eddy, S. R. Automated de novo identification of repeat sequence families in sequenced genomes. Genome Res. 12, 1269\u20131276 (2002)","journal-title":"Genome Res."},{"key":"BFnature12817_CR25","doi-asserted-by":"publisher","first-page":"i351","DOI":"10.1093\/bioinformatics\/bti1018","volume":"21","author":"AL Price","year":"2005","unstructured":"Price, A. L., Jones, N. C. & Pevzner, P. A. De novo identification of repeat families in large genomes. Bioinformatics 21, i351\u2013i358 (2005)","journal-title":"Bioinformatics"},{"key":"BFnature12817_CR26","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1093\/nar\/27.2.573","volume":"27","author":"G Benson","year":"1999","unstructured":"Benson, G. Tandem repeats finder: a program to analyze DNA sequences. Nucleic Acids Res. 27, 573\u2013580 (1999)","journal-title":"Nucleic Acids Res."},{"key":"BFnature12817_CR27","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1093\/bioinformatics\/btn013","volume":"24","author":"M Stanke","year":"2008","unstructured":"Stanke, M., Diekhans, M., Baertsch, R. & Haussler, D. Using native and syntenically mapped cDNA alignments to improve de novo gene finding. Bioinformatics 24, 637\u2013644 (2008)","journal-title":"Bioinformatics"},{"key":"BFnature12817_CR28","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1093\/nar\/25.5.955","volume":"25","author":"TM Lowe","year":"1997","unstructured":"Lowe, T. M. & Eddy, S. R. tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. Nucleic Acids Res. 25, 955\u2013964 (1997)","journal-title":"Nucleic Acids Res."},{"key":"BFnature12817_CR29","doi-asserted-by":"publisher","first-page":"3100","DOI":"10.1093\/nar\/gkm160","volume":"35","author":"K Lagesen","year":"2007","unstructured":"Lagesen, K. et al. RNAmmer: consistent and rapid annotation of ribosomal RNA genes. Nucleic Acids Res. 35, 3100\u20133108 (2007)","journal-title":"Nucleic Acids Res."},{"key":"BFnature12817_CR30","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","volume":"215","author":"SF Altschul","year":"1990","unstructured":"Altschul, S. F., Gish, W., Miller, W., Myers, E. W. & Lipman, D. J. Basic local alignment search tool. J. Mol. Biol. 215, 403\u2013410 (1990)","journal-title":"J. Mol. Biol."},{"key":"BFnature12817_CR31","doi-asserted-by":"publisher","first-page":"D226","DOI":"10.1093\/nar\/gks1005","volume":"41","author":"SW Burge","year":"2013","unstructured":"Burge, S. W. et al. Rfam 11.0: 10 years of RNA families. Nucleic Acids Res. 41, D226\u2013D232 (2013)","journal-title":"Nucleic Acids Res."},{"key":"BFnature12817_CR32","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1093\/nar\/gkg009","volume":"31","author":"JWS Brown","year":"2003","unstructured":"Brown, J. W. S. et al. Plant snoRNA database. Nucleic Acids Res. 31, 432\u2013435 (2003)","journal-title":"Nucleic Acids Res."},{"key":"BFnature12817_CR33","doi-asserted-by":"publisher","first-page":"D23","DOI":"10.1093\/nar\/gkh045","volume":"32","author":"DA Benson","year":"2004","unstructured":"Benson, D. A., Karsch-Mizrachi, I., Lipman, D. J., Ostell, J. & Wheeler, D. L. GenBank: update. Nucleic Acids Res. 32, D23\u2013D26 (2004)","journal-title":"Nucleic Acids Res."},{"key":"BFnature12817_CR34","doi-asserted-by":"publisher","first-page":"R102","DOI":"10.1186\/gb-2004-5-12-r102","volume":"5","author":"B-B Wang","year":"2004","unstructured":"Wang, B.-B. & Brendel, V. The ASRG database: identification and survey of Arabidopsis thaliana genes involved in pre-mRNA splicing. Genome Biol. 5, R102 (2004)","journal-title":"Genome Biol."},{"key":"BFnature12817_CR35","doi-asserted-by":"publisher","first-page":"1540","DOI":"10.1093\/bioinformatics\/btn230","volume":"24","author":"A Wehe","year":"2008","unstructured":"Wehe, A., Bansal, M. S., Burleigh, J. G. & Eulenstein, O. DupTree: a program for large-scale phylogenetic analyses using gene tree parsimony. Bioinformatics 24, 1540\u20131541 (2008)","journal-title":"Bioinformatics"},{"key":"BFnature12817_CR36","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1093\/sysbio\/syq010","volume":"59","author":"S Guindon","year":"2010","unstructured":"Guindon, S. et al. New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst. Biol. 59, 307\u2013321 (2010)","journal-title":"Syst. Biol."},{"key":"BFnature12817_CR37","doi-asserted-by":"publisher","first-page":"e49","DOI":"10.1093\/nar\/gkr1293","volume":"40","author":"Y Wang","year":"2012","unstructured":"Wang, Y. et al. MCScanX: a toolkit for detection and evolutionary analysis of gene synteny and collinearity. Nucleic Acids Res. 40, e49 (2012)","journal-title":"Nucleic Acids Res."},{"key":"BFnature12817_CR38","first-page":"418","volume":"3","author":"M Nei","year":"1986","unstructured":"Nei, M. & Gojobori, T. Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. Mol. Biol. Evol. 3, 418\u2013426 (1986)","journal-title":"Mol. Biol. Evol."},{"key":"BFnature12817_CR39","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1093\/bioinformatics\/17.9.847","volume":"17","author":"EM Zdobnov","year":"2001","unstructured":"Zdobnov, E. M. & Apweiler, R. InterProScan\u2013an integration platform for the signature-recognition methods in InterPro. Bioinformatics 17, 847\u2013848 (2001)","journal-title":"Bioinformatics"},{"key":"BFnature12817_CR40","doi-asserted-by":"crossref","unstructured":"UniProt Consortium. Reorganizing the protein space at the Universal Protein Resource (UniProt). Nucleic Acids Res. 40, D71\u2013D75 (2012)","DOI":"10.1093\/nar\/gkr981"},{"key":"BFnature12817_CR41","doi-asserted-by":"publisher","first-page":"D109","DOI":"10.1093\/nar\/gkr988","volume":"40","author":"M Kanehisa","year":"2012","unstructured":"Kanehisa, M., Goto, S., Sato, Y., Furumichi, M. & Tanabe, M. KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res. 40, D109\u2013D114 (2012)","journal-title":"Nucleic Acids Res."},{"key":"BFnature12817_CR42","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1186\/1471-2105-4-41","volume":"4","author":"RL Tatusov","year":"2003","unstructured":"Tatusov, R. L. et al. The COG database: an updated version includes eukaryotes. BMC Bioinformatics 4, 41 (2003)","journal-title":"BMC Bioinformatics"},{"key":"BFnature12817_CR43","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1007\/s10059-012-0003-8","volume":"33","author":"J Kim","year":"2012","unstructured":"Kim, J. et al. A genome-wide comparison of NB-LRR type of resistance gene analogs (RGA) in the plant kingdom. Mol. Cells 33, 385\u2013392 (2012)","journal-title":"Mol. Cells"},{"key":"BFnature12817_CR44","doi-asserted-by":"publisher","first-page":"D306","DOI":"10.1093\/nar\/gkr948","volume":"40","author":"S Hunter","year":"2012","unstructured":"Hunter, S. et al. InterPro in 2011: new developments in the family and domain prediction database. Nucleic Acids Res. 40, D306\u2013D312 (2012)","journal-title":"Nucleic Acids Res."},{"key":"BFnature12817_CR45","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1038\/nature10625","volume":"480","author":"ND Young","year":"2011","unstructured":"Young, N. D. et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature 480, 520\u2013524 (2011)","journal-title":"Nature"},{"key":"BFnature12817_CR46","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1016\/j.pbi.2010.02.001","volume":"13","author":"C K\u00fchn","year":"2010","unstructured":"K\u00fchn, C. & Grof, C. P. L. Sucrose transporters of higher plants. Curr. Opin. Plant Biol. 13, 287\u2013297 (2010)","journal-title":"Curr. Opin. Plant Biol."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/nature12817.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/nature12817","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/nature12817.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T04:18:37Z","timestamp":1650341917000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nature12817"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,18]]},"references-count":46,"journal-issue":{"issue":"7484","published-print":{"date-parts":[[2014,1,23]]}},"alternative-id":["BFnature12817"],"URL":"https:\/\/doi.org\/10.1038\/nature12817","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,18]]},"assertion":[{"value":"3 March 2013","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 October 2013","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 December 2013","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing financial interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}