{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T19:35:58Z","timestamp":1772134558087,"version":"3.50.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2004,2,22]],"date-time":"2004-02-22T00:00:00Z","timestamp":1077408000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Cell Biol"],"published-print":{"date-parts":[[2004,3]]},"DOI":"10.1038\/ncb1106","type":"journal-article","created":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T10:00:32Z","timestamp":1078135232000},"page":"244-251","source":"Crossref","is-referenced-by-count":192,"title":["Interactions of GGA3 with the ubiquitin sorting machinery"],"prefix":"10.1038","volume":"6","author":[{"given":"Rosa","family":"Puertollano","sequence":"first","affiliation":[]},{"given":"Juan S.","family":"Bonifacino","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2004,2,22]]},"reference":[{"key":"BFncb1106_CR1","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1091\/mbc.11.4.1241","volume":"11","author":"AL Boman","year":"2000","unstructured":"Boman, A.L., Zhang, C., Zhu, X. & Kahn, R.A. A family of ADP-ribosylation factor effectors that can alter membrane transport through the trans-Golgi. Mol. Biol. Cell. 11, 1241\u20131255 (2000).","journal-title":"Mol. Biol. Cell."},{"key":"BFncb1106_CR2","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1083\/jcb.149.1.81","volume":"149","author":"EC Dell'Angelica","year":"2000","unstructured":"Dell'Angelica, E.C. et al. GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complex. J. Cell Biol. 149, 81\u201394 (2000).","journal-title":"J. Cell Biol."},{"key":"BFncb1106_CR3","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1083\/jcb.149.1.67","volume":"49","author":"J Hirst","year":"2000","unstructured":"Hirst, J. et al. A family of proteins with \u03b3-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole\/lysosome. J. Cell Biol. 49, 67\u201380 (2000).","journal-title":"J. Cell Biol."},{"key":"BFncb1106_CR4","doi-asserted-by":"publisher","first-page":"1712","DOI":"10.1126\/science.1060750","volume":"292","author":"R Puertollano","year":"2001","unstructured":"Puertollano, R., Aguilar, R.C., Gorshkova, I., Crouch, R.J. & Bonifacino, J.S. Sorting of mannose 6-phosphate receptors mediated by the GGAs. Science 292, 1712\u20131716 (2001).","journal-title":"Science"},{"key":"BFncb1106_CR5","doi-asserted-by":"publisher","first-page":"1716","DOI":"10.1126\/science.1060896","volume":"292","author":"Y Zhu","year":"2001","unstructured":"Zhu, Y., Doray, B., Poussu, A., Lehto, V.P. & Kornfeld, S. Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6- phosphate receptor. Science 292, 1716\u20131718 (2001).","journal-title":"Science"},{"key":"BFncb1106_CR6","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1083\/jcb.200308038","volume":"163","author":"P Ghosh","year":"2003","unstructured":"Ghosh, P., Griffith, J., Geuze, H.J. & Kornfeld, S. Mammalian GGAs act together to sort mannose 6-phosphate receptors. J. Cell Biol. 163, 755\u2013766 (2003).","journal-title":"J. Cell Biol."},{"key":"BFncb1106_CR7","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/S0092-8674(01)00299-9","volume":"105","author":"R Puertollano","year":"2001","unstructured":"Puertollano, R., Randazzo, P., Hartnell, L.M., Presley, J. & Bonifacino, J.S. The GGAs promote ARF-dependent recruitment of clathrin to the TGN. Cell. 105, 93\u2013102 (2001).","journal-title":"Cell."},{"key":"BFncb1106_CR8","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1083\/jcb.200205078","volume":"158","author":"S Wasiak","year":"2002","unstructured":"Wasiak, S. et al. Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics. J. Cell Biol. 158, 855\u2013862 (2002).","journal-title":"J. Cell Biol."},{"key":"BFncb1106_CR9","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1093\/emboj\/cdg015","volume":"22","author":"R Mattera","year":"2003","unstructured":"Mattera, R., Arighi, C.N., Lodge, R., Zerial, M. & Bonifacino, J.S. Divalent interaction of the GGAs with the Rabaptin-5\u2013Rabex-5 complex. EMBO J. 22, 78\u201388 (2003).","journal-title":"EMBO J."},{"key":"BFncb1106_CR10","doi-asserted-by":"publisher","first-page":"2385","DOI":"10.1091\/mbc.e02-11-0735","volume":"14","author":"WW Lui","year":"2003","unstructured":"Lui, W.W. et al. Binding partners for the COOH-terminal appendage domains of the GGAs and \u03b3-adaptin. Mol. Biol. Cell 14, 2385\u20132398 (2003).","journal-title":"Mol. Biol. Cell"},{"key":"BFncb1106_CR11","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.1091\/mbc.02-07-0109","volume":"14","author":"R Puertollano","year":"2003","unstructured":"Puertollano, R. et al. Morphology and dynamics of clathrin\/GGA1-coated carriers budding from the trans-Golgi network. Mol. Biol. Cell 14, 1545\u20131557 (2003).","journal-title":"Mol. Biol. Cell"},{"key":"BFncb1106_CR12","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1083\/jcb.121.5.997","volume":"121","author":"J Klumperman","year":"1993","unstructured":"Klumperman, J. et al. Differences in the endosomal distributions of the two mannose 6-phosphate receptors. J. Cell Biol. 121, 997\u20131010 (1993).","journal-title":"J. Cell Biol."},{"key":"BFncb1106_CR13","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1083\/jcb.132.6.1011","volume":"132","author":"CE Futter","year":"1996","unstructured":"Futter, C.E., Pearse, A., Hewlett, L.J. & Hopkins, C.R. Multivesicular endosomes containing internalized EGF\u2013EGF receptor complexes mature and then directly with lysosomes. J. Cell Biol. 132, 1011\u20131023 (1996).","journal-title":"J. Cell Biol."},{"key":"BFncb1106_CR14","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1083\/jcb.200106056","volume":"156","author":"KE Longva","year":"2002","unstructured":"Longva, K.E. et al. Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies. J. Cell Biol. 156, 843\u2013854 (2002).","journal-title":"J. Cell Biol."},{"key":"BFncb1106_CR15","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1083\/jcb.200302131","volume":"162","author":"KG Bache","year":"2003","unstructured":"Bache, K.G., Brech, A., Mehlum, A. & Stenmark, H. Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes. J. Cell Biol. 162, 435\u2013442 (2003).","journal-title":"J. Cell Biol."},{"key":"BFncb1106_CR16","doi-asserted-by":"publisher","first-page":"12513","DOI":"10.1074\/jbc.M210843200","volume":"278","author":"KG Bache","year":"2003","unstructured":"Bache, K.G., Raiborg, C., Mehlum, A. & Stenmark, H. STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes. J. Biol. Chem. 278, 12513\u201312521 (2003).","journal-title":"J. Biol. Chem."},{"key":"BFncb1106_CR17","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1083\/jcb.200112080","volume":"157","author":"N Bishop","year":"2002","unstructured":"Bishop, N., Horman, A. & Woodman, P. Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein\u2013ubiquitin conjugates. J. Cell Biol. 157, 91\u2013101 (2002).","journal-title":"J. Cell Biol."},{"key":"BFncb1106_CR18","doi-asserted-by":"publisher","first-page":"7626","DOI":"10.1073\/pnas.0932599100","volume":"100","author":"Q Lu","year":"2003","unstructured":"Lu Q., Hope L.W., Brasch M., Reinhard C. & Cohen S.N. TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation. Proc. Natl Acad. Sci. USA 100, 7626\u20137631 (2003).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFncb1106_CR19","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/S0092-8674(01)00434-2","volume":"106","author":"DJ Katzmann","year":"2001","unstructured":"Katzmann, D.J., Babst, M. & Emr, S.D. Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 106, 145\u2013155 (2001).","journal-title":"Cell"},{"key":"BFncb1106_CR20","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1038\/ncb790","volume":"4","author":"SC Shih","year":"2002","unstructured":"Shih, S.C. et al. Epsins and Vps27p\/Hrs contain ubiquitin-binding domains that function in receptor endocytosis. Nature Cell Biol. 4, 389\u2013393 (2002).","journal-title":"Nature Cell Biol."},{"key":"BFncb1106_CR21","doi-asserted-by":"publisher","first-page":"3675","DOI":"10.1091\/mbc.e02-12-0823","volume":"14","author":"E Mizuno","year":"2003","unstructured":"Mizuno, E, Kawahata, K., Kato, M., Kitamura, N. & Komada, M. STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif. Mol. Biol. Cell. 14, 3675\u20133689 (2003).","journal-title":"Mol. Biol. Cell."},{"key":"BFncb1106_CR22","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1038\/415933a","volume":"415","author":"S Misra","year":"2002","unstructured":"Misra, S., Puertollano, R., Kato, Y., Bonifacino, J.S. & Hurley, J.H. Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Nature 415, 933\u2013937 (2002).","journal-title":"Nature"},{"key":"BFncb1106_CR23","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/S1534-5807(03)00037-6","volume":"4","author":"BM Collins","year":"2003","unstructured":"Collins, B.M., Watson, P.J. & Owen, D.J. The structure of the GGA1-GAT domain reveals the molecular basis for ARF binding and membrane association of GGAs. Dev. Cell 4, 321\u2013332 (2003).","journal-title":"Dev. Cell"},{"key":"BFncb1106_CR24","doi-asserted-by":"publisher","first-page":"4451","DOI":"10.1073\/pnas.0831133100","volume":"100","author":"S Suer","year":"2003","unstructured":"Suer, S., Misra, S., Saidi, L.F. & Hurley, J.H. Structure of the GAT domain of human GGA1: a syntaxin amino-terminal domain fold in an endosomal trafficking adaptor. Proc. Natl. Acad. Sci. USA 100, 4451\u20134456 (2003).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFncb1106_CR25","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1073\/pnas.93.2.861","volume":"93","author":"R Beal","year":"1996","unstructured":"Beal, R., Deveraux, Q., Xia, G., Rechsteiner, M. & Pickart, C. Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting. Proc. Natl Acad. Sci. USA 93, 861\u2013866 (1996).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFncb1106_CR26","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1093\/emboj\/19.2.187","volume":"19","author":"SC Shih","year":"2000","unstructured":"Shih, S.C., Sloper-Mould, K.E. & Hicke, L. Monoubiquitin carries a novel internalization signal that is appended to activated receptors. EMBO J. 19, 187\u2013198 (2000).","journal-title":"EMBO J."},{"key":"BFncb1106_CR27","doi-asserted-by":"publisher","first-page":"30483","DOI":"10.1074\/jbc.M103248200","volume":"276","author":"KE Sloper-Mould","year":"2001","unstructured":"Sloper-Mould, K.E., Jemc, J.C., Pickart, C.M. & Hicke, L. Distinct functional surface regions on ubiquitin. J. Biol. Chem. 276, 30483\u201330489 (2001).","journal-title":"J. Biol. Chem."},{"key":"BFncb1106_CR28","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/S0092-8674(03)00364-7","volume":"113","author":"G Prag","year":"2003","unstructured":"Prag, G. et al. Mechanism of ubiquitin recognition by the CUE domain of Vps9p. Cell. 113, 609\u2013620 (2003).","journal-title":"Cell."},{"key":"BFncb1106_CR29","doi-asserted-by":"publisher","first-page":"4597","DOI":"10.1093\/emboj\/cdg471","volume":"22","author":"KA Swanson","year":"2003","unstructured":"Swanson, K.A, Kang, R.S, Stamenova, S.D, Hicke, L. & Radhakrishnan, I. Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation. EMBO J. 22, 4597\u2013606 (2003).","journal-title":"EMBO J."},{"key":"BFncb1106_CR30","doi-asserted-by":"crossref","unstructured":"Shiba, Y. et al. GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination. J. Biol. Chem. (in the press).","DOI":"10.1074\/jbc.M311702200"},{"key":"BFncb1106_CR31","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1083\/jcb.200302138","volume":"162","author":"O Pornillos","year":"2003","unstructured":"Pornillos, O. et al. HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein. J. Cell Biol. 162, 425\u2013434 (2003).","journal-title":"J. Cell Biol."},{"key":"BFncb1106_CR32","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1091\/mbc.11.1.227","volume":"11","author":"N Bishop","year":"2000","unstructured":"Bishop, N. & Woodman, P. ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking. Mol. Biol. Cell. 11, 227\u2013239 (2000).","journal-title":"Mol. Biol. Cell."},{"key":"BFncb1106_CR33","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/S0006-291X(03)01032-5","volume":"306","author":"M Wakasugi","year":"2003","unstructured":"Wakasugi, M. et al. Predominant expression of the short form of GGA3 in human cell lines and tissues. Biochem. Biophys. Res. Commun. 306, 687\u2013692 (2003).","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"BFncb1106_CR34","doi-asserted-by":"publisher","first-page":"28541","DOI":"10.1074\/jbc.C100218200","volume":"276","author":"H Takatsu","year":"2001","unstructured":"Takatsu, H., Katoh, Y., Shiba, Y. & Nakayama, K. Golgi-localizing, \u03b3-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their vps27p\/hrs\/stam (VHS) domains. J. Biol. Chem. 276, 28541\u201328545 (2001).","journal-title":"J. Biol. Chem."}],"container-title":["Nature Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/ncb1106.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ncb1106","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ncb1106.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T15:23:27Z","timestamp":1684423407000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ncb1106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,2,22]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["BFncb1106"],"URL":"https:\/\/doi.org\/10.1038\/ncb1106","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1018156.223477","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.1018156.206503","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.1018156.206655","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.1018156.207531","asserted-by":"object"}]},"ISSN":["1465-7392","1476-4679"],"issn-type":[{"value":"1465-7392","type":"print"},{"value":"1476-4679","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,2,22]]}}}