{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T04:23:55Z","timestamp":1780547035236,"version":"3.54.1"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"65","license":[{"start":{"date-parts":[[1972,3,1]],"date-time":"1972-03-01T00:00:00Z","timestamp":68256000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature New Biology"],"published-print":{"date-parts":[[1972,3]]},"DOI":"10.1038\/newbio236107a0","type":"journal-article","created":{"date-parts":[[2013,7,24]],"date-time":"2013-07-24T10:52:29Z","timestamp":1374663149000},"page":"107-110","source":"Crossref","is-referenced-by-count":148,"title":["Aryl Hydrocarbon Hydroxylase Induction by Polycyclic Hydrocarbons: Simple Autosomal Dominant Trait in the Mouse"],"prefix":"10.1038","volume":"236","author":[{"given":"D. W.","family":"NEBERT","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. M.","family":"GOUJON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. E.","family":"GIELEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BFnewbio236107a0_CR1","first-page":"79","volume":"19","author":"HS Mason","year":"1957","unstructured":"Mason, H. S., Adv. Enzymol., 19, 79 (1957).","journal-title":"Adv. Enzymol."},{"key":"BFnewbio236107a0_CR2","first-page":"317","volume":"19","author":"AH Conney","year":"1967","unstructured":"Conney, A. H., Pharmacol. Rev., 19, 317 (1967).","journal-title":"Pharmacol. Rev."},{"key":"BFnewbio236107a0_CR3","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1073\/pnas.61.2.748","volume":"61","author":"R Tenhunen","year":"1968","unstructured":"Tenhunen, R., Marver, H. S., and Schmid, R., Proc. US Nat. Acad. Sci., 61, 748 (1968).","journal-title":"Proc. US Nat. Acad. Sci."},{"key":"BFnewbio236107a0_CR4","doi-asserted-by":"crossref","first-page":"3714","DOI":"10.1016\/S0021-9258(18)83427-5","volume":"244","author":"AYH Lu","year":"1969","unstructured":"Lu, A. Y. H., Junk, K. W., and Coon, M. J., J. Biol. Chem., 244, 3714 (1969).","journal-title":"J. Biol. Chem."},{"key":"BFnewbio236107a0_CR5","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/0003-9861(69)90253-7","volume":"134","author":"DW Nebert","year":"1969","unstructured":"Nebert, D. W., and Gelboin, H. V., Arch. Biochem. Biophys., 134, 76 (1969).","journal-title":"Arch. Biochem. Biophys."},{"key":"BFnewbio236107a0_CR6","doi-asserted-by":"crossref","first-page":"6242","DOI":"10.1016\/S0021-9258(18)94484-4","volume":"243","author":"DW Nebert","year":"1968","unstructured":"Nebert, D. W., and Gelboin, H. V., J. Biol. Chem., 243, 6242 (1968).","journal-title":"J. Biol. Chem."},{"key":"BFnewbio236107a0_CR7","doi-asserted-by":"crossref","first-page":"6250","DOI":"10.1016\/S0021-9258(18)94485-6","volume":"243","author":"DW Nebert","year":"1968","unstructured":"Nebert, D. W., and Gelboin, H. V., J. Biol. Chem., 243, 6250 (1968).","journal-title":"J. Biol. Chem."},{"key":"BFnewbio236107a0_CR8","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/S0021-9258(18)63434-9","volume":"245","author":"DW Nebert","year":"1970","unstructured":"Nebert, D. W., and Gelboin, H. V., J. Biol. Chem., 245, 160 (1970).","journal-title":"J. Biol. Chem."},{"key":"BFnewbio236107a0_CR9","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0021-9258(18)63363-0","volume":"245","author":"DW Nebert","year":"1970","unstructured":"Nebert, D. W., J. Biol. Chem., 245, 519 (1970).","journal-title":"J. Biol. Chem."},{"key":"BFnewbio236107a0_CR10","first-page":"293","volume":"6","author":"DW Nebert","year":"1970","unstructured":"Nebert, D. W., and Bausserman, L. L., Mol. Pharmacol., 6, 293 (1970).","journal-title":"Mol. Pharmacol."},{"key":"BFnewbio236107a0_CR11","first-page":"304","volume":"6","author":"DW Nebert","year":"1970","unstructured":"Nebert, D. W., and Bausserman, L. L., Mol. Pharmacol., 6, 304 (1970).","journal-title":"Mol. Pharmacol."},{"key":"BFnewbio236107a0_CR12","first-page":"6393","volume":"245","author":"DW Nebert","year":"1970","unstructured":"Nebert, D. W., and Bausserman, L. L., J. Biol. Chem., 245, 6393 (1970).","journal-title":"J. Biol. Chem."},{"key":"BFnewbio236107a0_CR13","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1111\/j.1749-6632.1971.tb46933.x","volume":"179","author":"DW Nebert","year":"1971","unstructured":"Nebert, D. W., and Bausserman, L. L., Proc. NY Acad. Sci., 179, 561 (1971).","journal-title":"Proc. NY Acad. Sci."},{"key":"BFnewbio236107a0_CR14","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1126\/science.172.3979.167","volume":"172","author":"JE Gielen","year":"1971","unstructured":"Gielen, J. E., and Nebert, D. W., Science, 172, 167 (1971).","journal-title":"Science"},{"key":"BFnewbio236107a0_CR15","doi-asserted-by":"crossref","first-page":"5189","DOI":"10.1016\/S0021-9258(18)61893-9","volume":"246","author":"JE Gielen","year":"1971","unstructured":"Gielen, J. E., and Nebert, D. W., J. Biol. Chem., 246, 5189 (1971).","journal-title":"J. Biol. Chem."},{"key":"BFnewbio236107a0_CR16","doi-asserted-by":"crossref","first-page":"5199","DOI":"10.1016\/S0021-9258(18)61894-0","volume":"246","author":"DW Nebert","year":"1971","unstructured":"Nebert, D. W., and Gielen, J. E., J. Biol. Chem., 246, 5199 (1971).","journal-title":"J. Biol. Chem."},{"key":"BFnewbio236107a0_CR17","unstructured":"Nebert, D. W., and Gielen, J. E., Fed. Proc. (in the press)."},{"key":"BFnewbio236107a0_CR18","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1056\/NEJM196004212621601","volume":"262","author":"CF Weiss","year":"1960","unstructured":"Weiss, C. F., Glazko, A. J., and Weston, J. K., New Engl. J. Med., 262, 787 (1960).","journal-title":"New Engl. J. Med."},{"key":"BFnewbio236107a0_CR19","first-page":"263","volume":"30","author":"M Watanabe","year":"1970","unstructured":"Watanabe, M., Potter, V. R., and Morris, H. P., Cancer Res., 30, 263 (1970).","journal-title":"Cancer Res."},{"key":"BFnewbio236107a0_CR20","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1016\/S0021-9258(19)45624-X","volume":"247","author":"JE Gielen","year":"1972","unstructured":"Gielen, J. E., Goujon, F. M., and Nebert, D. W., J. Biol. Chem., 247, 1125 (1972).","journal-title":"J. Biol. Chem."},{"key":"BFnewbio236107a0_CR21","first-page":"45","volume-title":"Biology of the Laboratory Mouse","author":"J Staats","year":"1966","unstructured":"Staats, J., in Biology of the Laboratory Mouse, second ed. (edit. by Green, E.), 45 (McGraw-Hill, New York, 1966)."},{"key":"BFnewbio236107a0_CR22","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/0065-2571(63)90019-0","volume":"1","author":"JR Gillette","year":"1963","unstructured":"Gillette, J. R., Adv. Enzyme Regul., 1, 215 (1963).","journal-title":"Adv. Enzyme Regul."},{"key":"BFnewbio236107a0_CR23","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S0026-895X(25)14658-0","volume":"5","author":"NE Sladek","year":"1969","unstructured":"Sladek, N. E., and Mannering, G. J., Mol. Pharmacol., 5, 174 (1969).","journal-title":"Mol. Pharmacol."},{"key":"BFnewbio236107a0_CR24","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/S0026-895X(25)14658-0","volume":"5","author":"NE Sladek","year":"1969","unstructured":"Sladek, N. E., and Mannering, G. J., Mol. Pharmacol., 5, 186 (1969).","journal-title":"Mol. Pharmacol."},{"key":"BFnewbio236107a0_CR25","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1016\/0003-9861(70)90494-7","volume":"139","author":"J Baron","year":"1970","unstructured":"Baron, J., and Tephly, T. R., Arch. Biochem. Biophys., 139, 410 (1970).","journal-title":"Arch. Biochem. Biophys."},{"key":"BFnewbio236107a0_CR26","volume-title":"Enzyme Synthesis and Degradation in Mammalian Systems","author":"K Paigen","year":"1971","unstructured":"Paigen, K., in Enzyme Synthesis and Degradation in Mammalian Systems (edit. by Rechcigl, jun., M.), ch. 9 (University Press, Baltimore, 1971)."},{"key":"BFnewbio236107a0_CR27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1146\/annurev.mi.16.100162.000245","volume":"16","author":"M Riley","year":"1962","unstructured":"Riley, M., and Pardee, A. B., Ann. Rev. Microbiol., 16, 1 (1962).","journal-title":"Ann. Rev. Microbiol."},{"key":"BFnewbio236107a0_CR28","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1126\/science.171.3971.581","volume":"171","author":"LC Terriere","year":"1971","unstructured":"Terriere, L. C., Yu, S. J., and Hoyer, R. F., Science, 171, 581 (1971).","journal-title":"Science"},{"key":"BFnewbio236107a0_CR29","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/S0021-9258(18)62457-3","volume":"246","author":"SR Gross","year":"1971","unstructured":"Gross, S. R., and Hutton, J. J., J. Biol. Chem., 246, 606 (1971).","journal-title":"J. Biol. Chem."},{"key":"BFnewbio236107a0_CR30","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1126\/science.173.3994.334","volume":"173","author":"RA Deitrich","year":"1971","unstructured":"Deitrich, R. A., Science, 173, 334 (1971).","journal-title":"Science"},{"key":"BFnewbio236107a0_CR31","first-page":"909","volume":"12","author":"LW Law","year":"1952","unstructured":"Law, L. W., Morrow, A. G., and Greenspan, E. M., J. Nat. Cancer Inst., 12, 909 (1952).","journal-title":"J. Nat. Cancer Inst."},{"key":"BFnewbio236107a0_CR32","doi-asserted-by":"crossref","first-page":"5511","DOI":"10.1016\/S0021-9258(18)96372-6","volume":"241","author":"DL Coleman","year":"1966","unstructured":"Coleman, D. L., J. Biol. Chem., 241, 5511 (1966).","journal-title":"J. Biol. Chem."},{"key":"BFnewbio236107a0_CR33","doi-asserted-by":"crossref","first-page":"5668","DOI":"10.1016\/S0021-9258(18)62706-1","volume":"245","author":"Y Sanno","year":"1970","unstructured":"Sanno, Y., Kolzer, M., and Schimke, R. T., J. Biol. Chem., 245, 5668 (1970).","journal-title":"J. Biol. Chem."},{"key":"BFnewbio236107a0_CR34","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1093\/genetics\/51.3.445","volume":"51","author":"FH Ruddle","year":"1965","unstructured":"Ruddle, F. H., and Roderick, T. H., Genetics, 51, 445 (1965).","journal-title":"Genetics"},{"key":"BFnewbio236107a0_CR35","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/S0006-291X(67)80049-4","volume":"27","author":"M Rechcigl jun.","year":"1967","unstructured":"Rechcigl, M., jun., and Heston, W. E., Biochem. Biophys. Res. Commun., 27, 119 (1967).","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"BFnewbio236107a0_CR36","unstructured":"Gelboin, H. V., Kinoshita, N., and Wiebel, F., Fed. Proc. (in the press)."},{"key":"BFnewbio236107a0_CR37","doi-asserted-by":"publisher","first-page":"2251","DOI":"10.1016\/0006-2952(70)90124-3","volume":"19","author":"PL Grover","year":"1970","unstructured":"Grover, P. L., and Sims, P., Biochem. Pharmacol., 19, 2251 (1970).","journal-title":"Biochem. Pharmacol."},{"key":"BFnewbio236107a0_CR38","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1073\/pnas.68.6.1098","volume":"68","author":"PL Grover","year":"1971","unstructured":"Grover, P. L., Sims, P., Huberman, E., Marquardt, H., Kuroki, T., and Heidelberger, C., Proc. US Nat. Acad. Sci., 68, 1098 (1971).","journal-title":"Proc. US Nat. Acad. Sci."},{"key":"BFnewbio236107a0_CR39","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.1016\/0006-291X(71)90562-6","volume":"43","author":"JK Selkirk","year":"1971","unstructured":"Selkirk, J. K., Huberman, E., and Heidelberger, C., Biochem. Biophys. Res. Commun., 43, 1010 (1971).","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"BFnewbio236107a0_CR40","unstructured":"Benedict, W. F., Gielen, J. E., and Nebert, D. W., Intern. J. Cancer (in the press)."}],"container-title":["Nature New Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/newbio236107a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/newbio236107a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/newbio236107a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T13:23:10Z","timestamp":1746019390000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/newbio236107a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1972,3]]},"references-count":40,"journal-issue":{"issue":"65","published-print":{"date-parts":[[1972,3]]}},"alternative-id":["BFnewbio236107a0"],"URL":"https:\/\/doi.org\/10.1038\/newbio236107a0","relation":{},"ISSN":["0090-0028","2058-1092"],"issn-type":[{"value":"0090-0028","type":"print"},{"value":"2058-1092","type":"electronic"}],"subject":[],"published":{"date-parts":[[1972,3]]}}}