{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T20:37:30Z","timestamp":1776371850648,"version":"3.51.2"},"reference-count":65,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1995,9,1]],"date-time":"1995-09-01T00:00:00Z","timestamp":809913600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Genet"],"published-print":{"date-parts":[[1995,9]]},"DOI":"10.1038\/ng0995-64","type":"journal-article","created":{"date-parts":[[2004,8,18]],"date-time":"2004-08-18T19:59:32Z","timestamp":1092859172000},"page":"64-70","source":"Crossref","is-referenced-by-count":305,"title":["MSH2 deficient mice are viable and susceptible to lymphoid tumours"],"prefix":"10.1038","volume":"11","author":[{"given":"A.H.","family":"Reitmair","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Schmits","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ewel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Bapat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Redston","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mitri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Waterhouse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.-W","family":"Mittr\u00fccker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Wakeham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Thomason","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Griesser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Gallinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.G.","family":"Ballhausen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Fishel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. W.","family":"Mak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BFng099564_CR1","doi-asserted-by":"publisher","first-page":"1535","DOI":"10.1016\/0016-5085(93)90368-M","volume":"104","author":"HT Lynch","year":"1993","unstructured":"Lynch, H.T. et al. Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review. Gastroenterology 104, 1535\u20131549 (1993).","journal-title":"Gastroenterology"},{"key":"BFng099564_CR2","doi-asserted-by":"publisher","first-page":"3493","DOI":"10.1002\/1097-0142(19930601)71:11<3493::AID-CNCR2820711106>3.0.CO;2-H","volume":"71","author":"M Ponz de Leon","year":"1993","unstructured":"Ponz de Leon, M., Sassatelli, R., Benatti, P. & Roncucci, L. Identification of hereditary nonpolyposis colorectal cancer in the general population. The 6-year experience of a population-based registry. Cancer 71, 3493\u20133501 (1993).","journal-title":"Cancer"},{"key":"BFng099564_CR3","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1136\/gut.32.5.509","volume":"32","author":"F Kee","year":"1991","unstructured":"Kee, F. & Collins, B.J. How prevalent is cancer family syndrome? Gut 32, 509\u2013512 (1991).","journal-title":"Gut"},{"key":"BFng099564_CR4","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1056\/NEJM198809013190902","volume":"319","author":"LA Cannon Albright","year":"1988","unstructured":"Cannon Albright, L.A., Skolnick, M.H., Bishop, D.T., Lee, R.G. & Burt, R.W. Common inheritance of susceptibility to colonic adenomatous polyps and associated colorectal cancers. New Engl. J. Med. 319, 533\u2013537 (1988).","journal-title":"New Engl. J. Med."},{"key":"BFng099564_CR5","first-page":"585","volume":"9","author":"DT Bishop","year":"1990","unstructured":"Bishop, D.T. & Thomas, H.J. The genetics of colorectal cancer. Cancer Surv. 9, 585\u2013604 (1990).","journal-title":"Cancer Surv."},{"key":"BFng099564_CR6","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1126\/science.8484120","volume":"260","author":"P Peltomaki","year":"1993","unstructured":"Peltomaki, P. et al. Genetic mapping of a locus predisposing to human colorectal cancer. Science 260, 810\u2013812 (1993).","journal-title":"Science"},{"key":"BFng099564_CR7","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1038\/ng1193-279","volume":"5","author":"A Lindblom","year":"1993","unstructured":"Lindblom, A., Tannergard, P., Werelius, B. & Nordenskjold, M. Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer. Nature Genet. 5, 279\u2013282 (1993).","journal-title":"Nature Genet."},{"key":"BFng099564_CR8","first-page":"659","volume":"55","author":"M Nystrom-Lahti","year":"1994","unstructured":"Nystrom-Lahti, M. et al. Mismatch repair genes on chromosomes 2p and 3p account for a major share of hereditary nonpolyposis colorectal cancer families evaluable by linkage. Am. J. hum. Genet. 55, 659\u2013665 (1994).","journal-title":"Am. J. hum. Genet."},{"key":"BFng099564_CR9","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1016\/0092-8674(93)90546-3","volume":"75","author":"R Fishel","year":"1993","unstructured":"Fishel, R. et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 75, 1027\u20131038 (1993).","journal-title":"Cell"},{"key":"BFng099564_CR10","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1016\/0092-8674(93)90330-S","volume":"75","author":"FS Leach","year":"1993","unstructured":"Leach, F.S. et al. Mutations of a MutS homolog in hereditary nonpolyposis colorectal cancer. Cell 75, 1215\u20131225 (1993).","journal-title":"Cell"},{"key":"BFng099564_CR11","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1038\/368258a0","volume":"368","author":"CE Bronner","year":"1994","unstructured":"Bronner, C.E. et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 368, 258\u2013261 (1994).","journal-title":"Nature"},{"key":"BFng099564_CR12","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.1126\/science.8128251","volume":"263","author":"N Papadopoulos","year":"1994","unstructured":"Papadopoulos, N. et al. Mutation of a MutL homolog in hereditary colon cancer. Science 263, 1625\u20131629 (1994).","journal-title":"Science"},{"key":"BFng099564_CR13","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1146\/annurev.ge.25.120191.001305","volume":"25","author":"P Modrich","year":"1991","unstructured":"Modrich, P. Mechanisms and biological effects of mismatch repair. Annu. Rev. Genet. 25, 229\u2013253 (1991).","journal-title":"Annu. Rev. Genet."},{"key":"BFng099564_CR14","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1016\/0959-437X(95)80055-7","volume":"5","author":"R Fishel","year":"1995","unstructured":"Fishel, R. & Kolodner, R.D. Identification of mismatch repair genes and their role in development of cancer. Curr. Opin. Genet. Dev. 5, 382\u2013395 (1995).","journal-title":"Curr. Opin. Genet. Dev."},{"key":"BFng099564_CR15","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1038\/371075a0","volume":"371","author":"NC Nicolaides","year":"1994","unstructured":"Nicolaides, N.C. et al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 371, 75\u201380 (1994).","journal-title":"Nature"},{"key":"BFng099564_CR16","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1126\/science.7632227","volume":"268","author":"R Parsons","year":"1995","unstructured":"Parsons, R., Longley, M., Kinzler, K.W. & Vogelstein, B. Mismatch repair deficiency in phenotypically normal human-cells. Science 268, 738\u2013740 (1995).","journal-title":"Science"},{"key":"BFng099564_CR17","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1126\/science.8484121","volume":"260","author":"LA Aaltonen","year":"1993","unstructured":"Aaltonen, L.A. et al. Clues to the pathogenesis of familial colorectal cancer. Science 260, 812\u2013816 (1993).","journal-title":"Science"},{"key":"BFng099564_CR18","doi-asserted-by":"publisher","first-page":"5323","DOI":"10.1093\/nar\/15.13.5323","volume":"15","author":"G Levinson","year":"1987","unstructured":"Levinson, G. & Gutman, G.A. High frequencies of short frameshifts in poly-CA\/TG tandem repeats borne by bacteriophage M13 in Escherichia coli K-12. Nucl. Acids Res. 15, 5323\u20135338 (1987).","journal-title":"Nucl. Acids Res."},{"key":"BFng099564_CR19","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1038\/365274a0","volume":"365","author":"M Strand","year":"1993","unstructured":"Strand, M., Prolla, T.A., Liskay, R.M. & Petes, T.D. Destabilization of tracts of simple repetitive DMA in yeast by mutations affecting DNA mismatch repair. Nature 365, 274\u2013276 (1993).","journal-title":"Nature"},{"key":"BFng099564_CR20","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1038\/363558a0","volume":"363","author":"Y Ionov","year":"1993","unstructured":"Ionov, Y., Peinado, M.A., Malkhosyan, S., Shibata, D. & Perucho, M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 363, 558\u2013561 (1993).","journal-title":"Nature"},{"key":"BFng099564_CR21","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1126\/science.8484122","volume":"260","author":"SN Thibodeau","year":"1993","unstructured":"Thibodeau, S.N., Bren, G. & Schaid, D. Microsatellite instability in cancer of the proximal colon. Science 260, 816\u2013819 (1993).","journal-title":"Science"},{"key":"BFng099564_CR22","first-page":"5100","volume":"53","author":"JI Risinger","year":"1993","unstructured":"Risinger, J.I. et al. Genetic instability of microsatellites in endometrial carcinoma. Cancer Res. 53, 5100\u20135103 (1993).","journal-title":"Cancer Res."},{"key":"BFng099564_CR23","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1002\/humu.1380020505","volume":"2","author":"J Young","year":"1993","unstructured":"Young, J. et al. Genomic instability occurs in colorectal carcinomas but not in adenomas. Hum. Mut. 2, 351\u2013354 (1993).","journal-title":"Hum. Mut."},{"key":"BFng099564_CR24","first-page":"5087","volume":"53","author":"HJ Han","year":"1993","unstructured":"Han, H.J., Yanagisawa, A., Kato, Y., Park, J.G. & Nakamura, Y. Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer. Cancer Res. 53, 5087\u20135089 (1993).","journal-title":"Cancer Res."},{"key":"BFng099564_CR25","first-page":"5853","volume":"53","author":"P Peltomaki","year":"1993","unstructured":"Peltomaki, P. et al. Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome. Cancer Res. 53, 5853\u20135855 (1993).","journal-title":"Cancer Res."},{"key":"BFng099564_CR26","first-page":"5620","volume":"53","author":"M Gonzalez-Zulueta","year":"1993","unstructured":"Gonzalez-Zulueta, M. et al. Microsatellite instability in bladder cancer. Cancer Res. 53, 5620\u20135623 (1993).","journal-title":"Cancer Res."},{"key":"BFng099564_CR27","first-page":"29","volume":"9","author":"MG Rhyu","year":"1994","unstructured":"Rhyu, M.G., Park, W.S. & Meltzer, S.J. Microsatellite instability occurs frequently in human gastric carcinoma. Oncogene 9, 29\u201332 (1994).","journal-title":"Oncogene"},{"key":"BFng099564_CR28","doi-asserted-by":"crossref","first-page":"3449","DOI":"10.1182\/blood.V83.12.3449.3449","volume":"83","author":"C Wada","year":"1994","unstructured":"Wada, C. et al. Genomic instability of microsatellite repeats and its association with the evolution of chronic myelogenous leukemia. Blood 83, 3449\u20133456 (1994).","journal-title":"Blood"},{"key":"BFng099564_CR29","first-page":"2084","volume":"54","author":"V Shridhar","year":"1994","unstructured":"Shridhar, V., Siegfried, J., Hunt, J., del Mar Alonso, M. & Smith, D.I. Genetic instability of microsatellite sequences in many non-small cell lung carcinomas. Cancer Res. 54, 2084\u20132087 (1994).","journal-title":"Cancer Res."},{"key":"BFng099564_CR30","first-page":"2098","volume":"54","author":"A Merlo","year":"1994","unstructured":"Merlo, A. et al. Frequent microsatellite instability in primary small cell lung cancer. Cancer Res. 54, 2098\u20132101 (1994).","journal-title":"Cancer Res."},{"key":"BFng099564_CR31","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1038\/ng0294-152","volume":"6","author":"R Wooster","year":"1994","unstructured":"Wooster, R. et al. Instability of shorttandem repeats (microsatellites) in human cancers. Nature Genet. 6, 152\u2013156 (1994).","journal-title":"Nature Genet."},{"key":"BFng099564_CR32","first-page":"1641","volume":"54","author":"CJ Yee","year":"1994","unstructured":"Yee, C.J., Roodi, N., Verrier, C.S. & Parl, F.F. Microsatellite instability and loss of heterozygosity in breast cancer. Cancer Res. 54, 1641\u20131644 (1994).","journal-title":"Cancer Res."},{"key":"BFng099564_CR33","first-page":"1163","volume":"9","author":"RT Burks","year":"1994","unstructured":"Burks, R.T., Kessis, T.D., Cho, K.R. & Hedrick, L. Microsatellite instability in endometrial carcinoma. Oncogene 9, 1163\u20131166 (1994).","journal-title":"Oncogene"},{"key":"BFng099564_CR34","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1006\/bbrc.1994.1011","volume":"198","author":"MP Schoenberg","year":"1994","unstructured":"Schoenberg, M.P. et al. Microsatellite mutation (CAG24\u219218) in the androgen receptor gene in human prostate cancer. Biochem. Biophys. Res. Commun. 198, 74\u201380 (1994).","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"BFng099564_CR35","first-page":"1159","volume":"54","author":"R Honchel","year":"1994","unstructured":"Honchel, R., Halling, K.C., Schaid, D.J., Pittelkow, M. & Thibodeau, S.N. Microsatellite instability in Muir-Torre syndrome. Cancer Res. 54, 1159\u20131163 (1994).","journal-title":"Cancer Res."},{"key":"BFng099564_CR36","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1038\/ng0394-273","volume":"6","author":"D Shibata","year":"1994","unstructured":"Shibata, D., Peinado, M.A., Ionov, Y., Malkhosyan, S. & Perucho, M. Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation. Nature Genet. 6, 273\u2013281 (1994).","journal-title":"Nature Genet."},{"key":"BFng099564_CR37","first-page":"1645","volume":"54","author":"LA Aaltonen","year":"1994","unstructured":"Aaltonen, L.A. et al. Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients. Cancer Res. 54, 1645\u20131648 (1994).","journal-title":"Cancer Res."},{"key":"BFng099564_CR38","doi-asserted-by":"publisher","first-page":"1403","DOI":"10.1126\/science.7973733","volume":"266","author":"R Fishel","year":"1994","unstructured":"Fishel, R., Ewel, A., Lee, S., Lescoe, M.K. & Griffith, J. Binding of mismatched microsatellite DNA sequences by the human MSH2 protein. Science 266, 1403\u20131405 (1994).","journal-title":"Science"},{"key":"BFng099564_CR39","first-page":"5539","volume":"54","author":"R Fishel","year":"1994","unstructured":"Fishel, R., Ewel, A. & Lescoe, M.K. Purified human MSH2 protein binds to DNA containing mismatched nucleotides. Cancer Res. 54, 5539\u20135542 (1994).","journal-title":"Cancer Res."},{"key":"BFng099564_CR40","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1038\/365207a0","volume":"365","author":"TA Kunkel","year":"1993","unstructured":"Kunkel, T.A. Nucleotide repeats. Slippery DNA and diseases. Nature 365, 207\u2013208 (1993).","journal-title":"Nature"},{"key":"BFng099564_CR41","doi-asserted-by":"publisher","first-page":"1909","DOI":"10.1126\/science.7604264","volume":"268","author":"JT Drummond","year":"1995","unstructured":"Drummond, J.T., Guo-Min, I., Longley, M.J. & Modrich, P. Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells. Science 268, 1909\u20131912 (1995).","journal-title":"Science"},{"key":"BFng099564_CR42","doi-asserted-by":"publisher","first-page":"1912","DOI":"10.1126\/science.7604265","volume":"268","author":"F Palombo","year":"1995","unstructured":"Palombo, F. et al. GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells. Science 268, 1912\u20131914 (1995).","journal-title":"Science"},{"key":"BFng099564_CR43","doi-asserted-by":"publisher","first-page":"1915","DOI":"10.1126\/science.7604266","volume":"268","author":"N Papadopoulos","year":"1995","unstructured":"Papadopoulos, N. et al. Mutations of GTBP in genetically unstable cells. Science 268, 1915\u20131917 (1995).","journal-title":"Science"},{"key":"BFng099564_CR44","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/0022-2836(86)90300-1","volume":"188","author":"RA Fishel","year":"1986","unstructured":"Fishel, R.A., Siegel, E.C. & Kolodner, R. Gene conversion in Escherichia coli. Resolution of heteroallelic mismatched nucleotides by co-repair. J. molec. Biol. 188, 147\u2013157 (1986).","journal-title":"J. molec. Biol."},{"key":"BFng099564_CR45","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1093\/genetics\/113.1.13","volume":"113","author":"SI Feinstein","year":"1986","unstructured":"Feinstein, S.I. & Low, K.B. Hyper-recombining recipient strains in bacterial conjugation. Genetics 113, 13\u201333 (1986).","journal-title":"Genetics"},{"key":"BFng099564_CR46","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1016\/0092-8674(87)90035-3","volume":"50","author":"M Jones","year":"1987","unstructured":"Jones, M., Wagner, R. & Radman, M. Mismatch repair and recombination in E. coli. Cell 50, 621\u2013626 (1987).","journal-title":"Cell"},{"key":"BFng099564_CR47","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1093\/genetics\/137.1.19","volume":"137","author":"E Alani","year":"1994","unstructured":"Alani, E., Reenan, R.A. & Kolodner, R.D. Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae. Genetics 137, 19\u201339 (1994).","journal-title":"Genetics"},{"key":"BFng099564_CR48","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1038\/342396a0","volume":"342","author":"C Rayssiguier","year":"1989","unstructured":"Rayssiguier, C., Thaler, D.S. & Radman, M. The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants. Nature 342, 396\u2013401 (1989).","journal-title":"Nature"},{"key":"BFng099564_CR49","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1093\/genetics\/139.3.1175","volume":"139","author":"EM Selva","year":"1995","unstructured":"Selva, E.M., New, L. & Lahue, R.S. Mismatch correction acts as a barrier to homeologous recombination in saccharomyces-cerevisiae. Genetics 139, 1175\u20131188H1 Amge (1995).","journal-title":"Genetics"},{"key":"BFng099564_CR50","first-page":"3075","volume":"51","author":"LA Loeb","year":"1991","unstructured":"Loeb, L.A. Mutator phenotype may be required for multistage carcinogenesis. Cancer Res. 51, 3075\u20133079 (1991).","journal-title":"Cancer Res."},{"key":"BFng099564_CR51","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/0092-8674(95)90318-6","volume":"82","author":"SM Baker","year":"1995","unstructured":"Baker, S.M. et al. Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis. Cell 82, 302\u2013319 (1995).","journal-title":"Cell"},{"key":"BFng099564_CR52","first-page":"337","volume":"18","author":"HT Lynch","year":"1991","unstructured":"Lynch, H.T. et al. Hereditary colorectal cancer. Semin. Oncol. 18, 337\u2013366 (1991).","journal-title":"Semin. Oncol."},{"key":"BFng099564_CR53","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1002\/ajh.2830400114","volume":"40","author":"PR Cohen","year":"1992","unstructured":"Cohen, P.R. Muir-Torre syndrome in patients with hematologic malignancies. Am. J. Hemat. 40, 64\u201365 (1992).","journal-title":"Am. J. Hemat."},{"key":"BFng099564_CR54","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1056\/NEJM199503303321302","volume":"332","author":"SR Hamilton","year":"1995","unstructured":"Hamilton, S.R. et al. The molecular-basis of Turcots-syndrome. New Engl. J. Med. 332, 839\u2013847 (1995).","journal-title":"New Engl. J. Med."},{"key":"BFng099564_CR55","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.1016\/0092-8674(93)90331-J","volume":"75","author":"R Parsons","year":"1993","unstructured":"Parsons, R. et al. Hypermutability and mismatch repair deficiency in RER+ tumor cells. Cell 75, 1227\u20131236 (1993).","journal-title":"Cell"},{"key":"BFng099564_CR56","doi-asserted-by":"publisher","first-page":"6319","DOI":"10.1073\/pnas.91.14.6319","volume":"91","author":"NP Bhattacharyya","year":"1994","unstructured":"Bhattacharyya, N.P., Skandalis, A., Ganesh, A., Groden, J. & Meuth, M. Mutator phenotypes in human colorectal carcinoma cell lines. Proc. natn. Acad. Sci. U.S.A. 91, 6319\u20136323 (1994).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BFng099564_CR57","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/0092-8674(87)90552-6","volume":"49","author":"CM Croce","year":"1987","unstructured":"Croce, C.M. Role of chromosome translocations in human neoplasia. Cell 49, 155\u2013156 (1987).","journal-title":"Cell"},{"key":"BFng099564_CR58","first-page":"785","volume-title":"Pathogenesis of Retrovirous Induced Disease in RNA tumor viruses","author":"N Teich","year":"1984","unstructured":"Teich, N., Wyke, J., Mak, T., Bernstein, A. & Hardy, W. Pathogenesis of Retrovirous Induced Disease in RNA tumor viruses. (eds Weiss, R., Teich, N., Varmus, H. & Coffin, J.) 785\u2013998 (Cold Spring Harbor Laboratory, Cold Spring Harbor, 1984)."},{"key":"BFng099564_CR59","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1016\/0092-8674(91)90011-M","volume":"65","author":"VL Tybulewicz","year":"1991","unstructured":"Tybulewicz, V.L., Crawford, C.E., Jackson, P.K., Bronson, R.T., Mulligan, R.C. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell 65, 1153\u20131163 (1991).","journal-title":"Cell"},{"key":"BFng099564_CR60","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1016\/0092-8674(91)90462-8","volume":"65","author":"WP Fung Leung","year":"1991","unstructured":"Fung Leung, W.P. et al. CD8 is needed for development of cytotoxic T cells but not helper T cells. Cell 65, 443\u2013449 (1991).","journal-title":"Cell"},{"key":"BFng099564_CR61","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1038\/309255a0","volume":"309","author":"A Bradley","year":"1984","unstructured":"Bradley, A., Evans, M., Kaufman, M.H., Robertson, E. Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature 309, 255\u2013256 (1984).","journal-title":"Nature"},{"key":"BFng099564_CR62","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1016\/S0070-2153(08)60675-4","volume":"20","author":"A Bradley","year":"1986","unstructured":"Bradley, A. & Robertson, E. Embryo-derived stem cells: atool for elucidating the developmental genetics of the mouse. Curr. Top. Dev. Biol. 20, 357\u2013371 (1986).","journal-title":"Curr. Top. Dev. Biol."},{"key":"BFng099564_CR63","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1016\/0092-8674(87)90646-5","volume":"51","author":"KR Thomas","year":"1987","unstructured":"Thomas, K.R. & Capecchi, M.R. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51, 503\u2013512 (1987).","journal-title":"Cell"},{"key":"BFng099564_CR64","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/0092-8674(89)90905-7","volume":"56","author":"S Thompson","year":"1989","unstructured":"Thompson, S., Clarke, A.R., Pow, A.M., Hooper, M.L., Melton, D.W. Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells. Cell 56, 313\u2013321 (1989).","journal-title":"Cell"},{"key":"BFng099564_CR65","volume-title":"Molecular Cloning","author":"T Maniatis","year":"1982","unstructured":"Maniatis, T., Fritsch, E.F. & Sambrook, J. Molecular Cloning. (Cold Spring Harbor Laboratory, Cold Spring Harbor, 1982)."}],"container-title":["Nature Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/ng0995-64","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ng0995-64.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ng0995-64.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T20:58:31Z","timestamp":1684443511000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ng0995-64"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,9]]},"references-count":65,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1995,9]]}},"alternative-id":["BFng099564"],"URL":"https:\/\/doi.org\/10.1038\/ng0995-64","relation":{},"ISSN":["1061-4036","1546-1718"],"issn-type":[{"value":"1061-4036","type":"print"},{"value":"1546-1718","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,9]]}}}