{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T16:59:20Z","timestamp":1785603560619,"version":"3.56.0"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"7756","license":[{"start":{"date-parts":[[2019,5,8]],"date-time":"2019-05-08T00:00:00Z","timestamp":1557273600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2019,5,8]],"date-time":"2019-05-08T00:00:00Z","timestamp":1557273600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[2019,5,16]]},"DOI":"10.1038\/s41586-019-1185-4","type":"journal-article","created":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T01:05:27Z","timestamp":1557363927000},"page":"438-442","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":173,"title":["An ultra-stable gold-coordinated protein cage displaying reversible assembly"],"prefix":"10.1038","volume":"569","author":[{"given":"Ali D.","family":"Malay","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoyuki","family":"Miyazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Artur","family":"Biela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soumyananda","family":"Chakraborti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina","family":"Majsterkiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izabela","family":"Stupka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig S.","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Kowalczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard M. A. G.","family":"Piette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg K. A.","family":"Hochberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz P.","family":"Wrobel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Fineberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manish S.","family":"Kushwah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitja","family":"Kelemen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Primo\u017e","family":"Vavpeti\u010d","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Primo\u017e","family":"Pelicon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Kukura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin L. P.","family":"Benesch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Iwasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan G.","family":"Heddle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,5,8]]},"reference":[{"key":"1185_CR1","doi-asserted-by":"publisher","first-page":"3433","DOI":"10.1039\/C7CS00818J","volume":"47","author":"WM Aumiller","year":"2018","unstructured":"Aumiller, W. M., Uchida, M. & Douglas, T. Protein cage assembly across multiple length scales. Chem. Soc. Rev. 47, 3433\u20133469 (2018).","journal-title":"Chem. Soc. Rev."},{"key":"1185_CR2","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1126\/science.aaf8818","volume":"353","author":"JB Bale","year":"2016","unstructured":"Bale, J. B. et al. Accurate design of megadalton-scale two-component icosahedral protein complexes. Science 353, 389\u2013394 (2016).","journal-title":"Science"},{"key":"1185_CR3","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1146\/annurev-biophys-070816-033928","volume":"46","author":"TO Yeates","year":"2017","unstructured":"Yeates, T. O. Geometric principles for designing highly symmetric self-assembling protein nanomaterials. Annu. Rev. Biophys. 46, 23\u201342 (2017).","journal-title":"Annu. Rev. Biophys."},{"key":"1185_CR4","doi-asserted-by":"publisher","first-page":"2217","DOI":"10.1073\/pnas.041614998","volume":"98","author":"JE Padilla","year":"2001","unstructured":"Padilla, J. E., Colovos, C. & Yeates, T. O. Nanohedra: using symmetry to design self assembling protein cages, layers, crystals, and filaments. Proc. Natl Acad. Sci. USA 98, 2217\u20132221 (2001).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"1185_CR5","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1126\/science.1219364","volume":"336","author":"NP King","year":"2012","unstructured":"King, N. P. et al. Computational design of self-assembling protein nanomaterials with atomic level accuracy. Science 336, 1171\u20131174 (2012).","journal-title":"Science"},{"key":"1185_CR6","doi-asserted-by":"publisher","first-page":"2022","DOI":"10.1002\/1521-3773(20010601)40:11<2022::AID-ANIE2022>3.0.CO;2-D","volume":"40","author":"BJ Holliday","year":"2001","unstructured":"Holliday, B. J. & Mirkin, C. A. Strategies for the construction of supramolecular compounds through coordination chemistry. Angew. Chem. Int. Ed. 40, 2022\u20132043 (2001).","journal-title":"Angew. Chem. Int. Ed."},{"key":"1185_CR7","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1021\/ar900273t","volume":"43","author":"EN Salgado","year":"2010","unstructured":"Salgado, E. N., Radford, R. J. & Tezcan, F. A. Metal-directed protein self-assembly. Acc. Chem. Res. 43, 661\u2013672 (2010).","journal-title":"Acc. Chem. Res."},{"key":"1185_CR8","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1038\/nchem.1290","volume":"4","author":"JD Brodin","year":"2012","unstructured":"Brodin, J. D. et al. Metal-directed, chemically tunable assembly of one-, two- and three-dimensional crystalline protein arrays. Nat. Chem. 4, 375\u2013382 (2012).","journal-title":"Nat. Chem."},{"key":"1185_CR9","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1021\/ja208015j","volume":"134","author":"BS Der","year":"2012","unstructured":"Der, B. S. et al. Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer. J. Am. Chem. Soc. 134, 375\u2013385 (2012).","journal-title":"J. Am. Chem. Soc."},{"key":"1185_CR10","doi-asserted-by":"publisher","first-page":"5847","DOI":"10.1039\/c2nr31244a","volume":"4","author":"W Zhang","year":"2012","unstructured":"Zhang, W. et al. Self-assembly of glutathione S-transferase into nanowires. Nanoscale 4, 5847\u20135851 (2012).","journal-title":"Nanoscale"},{"key":"1185_CR11","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1038\/nchembio.1163","volume":"9","author":"DJE Huard","year":"2013","unstructured":"Huard, D. J. E., Kane, K. M. & Tezcan, F. A. Re-engineering protein interfaces yields copper-inducible ferritin cage assembly. Nat. Chem. Biol. 9, 169\u2013176 (2013).","journal-title":"Nat. Chem. Biol."},{"key":"1185_CR12","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1038\/374693a0","volume":"374","author":"AA Antson","year":"1995","unstructured":"Antson, A. A. et al. The structure of trp RNA-binding attenuation protein. Nature 374, 693\u2013700 (1995).","journal-title":"Nature"},{"key":"1185_CR13","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1016\/j.str.2006.03.013","volume":"14","author":"JG Heddle","year":"2006","unstructured":"Heddle, J. G., Yokoyama, T., Yamashita, I., Park, S.-Y. & Tame, J. R. H. Rounding up: engineering 12-membered rings from the cyclic 11-mer TRAP. Structure 14, 925\u2013933 (2006).","journal-title":"Structure"},{"key":"1185_CR14","doi-asserted-by":"publisher","first-page":"1950","DOI":"10.1002\/smll.200700400","volume":"3","author":"JG Heddle","year":"2007","unstructured":"Heddle, J. G. et al. Using the ring-shaped protein TRAP to capture and confine gold nanodots on a surface. Small 3, 1950\u20131956 (2007).","journal-title":"Small"},{"key":"1185_CR15","doi-asserted-by":"publisher","first-page":"2077","DOI":"10.1002\/smll.200900667","volume":"5","author":"FF Miranda","year":"2009","unstructured":"Miranda, F. F. et al. A self-assembled protein nanotube with high aspect ratio. Small 5, 2077\u20132084 (2009).","journal-title":"Small"},{"key":"1185_CR16","doi-asserted-by":"publisher","first-page":"2056","DOI":"10.1021\/nl3002155","volume":"12","author":"AD Malay","year":"2012","unstructured":"Malay, A. D. et al. Gold nanoparticle-induced formation of artificial protein capsids. Nano Lett. 12, 2056\u20132059 (2012).","journal-title":"Nano Lett."},{"key":"1185_CR17","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1021\/nl5045617","volume":"15","author":"M Imamura","year":"2015","unstructured":"Imamura, M. et al. Probing structural dynamics of an artificial protein cage using high-speed atomic force microscopy. Nano Lett. 15, 1331\u20131335 (2015).","journal-title":"Nano Lett."},{"key":"1185_CR18","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1126\/science.aar5839","volume":"360","author":"G Young","year":"2018","unstructured":"Young, G. et al. Quantitative mass imaging of single biological macromolecules. Science 360, 423\u2013427 (2018).","journal-title":"Science"},{"key":"1185_CR19","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1038\/nchem.1352","volume":"4","author":"H H\u00e4kkinen","year":"2012","unstructured":"H\u00e4kkinen, H. The gold\u2013sulfur interface at the nanoscale. Nat. Chem. 4, 443\u2013455 (2012).","journal-title":"Nat. Chem."},{"key":"1185_CR20","doi-asserted-by":"publisher","first-page":"2099","DOI":"10.1039\/c0dt01057j","volume":"40","author":"KP Bhabak","year":"2011","unstructured":"Bhabak, K. P., Bhuyan, B. J. & Mugesh, G. Bioinorganic and medicinal chemistry: aspects of gold(i)-protein complexes. Dalton Trans. 40, 2099\u20132111 (2011).","journal-title":"Dalton Trans."},{"key":"1185_CR21","doi-asserted-by":"publisher","first-page":"1881","DOI":"10.1002\/anie.200502756","volume":"45","author":"S Urig","year":"2006","unstructured":"Urig, S. et al. Undressing of phosphine gold(i) complexes as irreversible inhibitors of human disulfide reductases. Angew. Chem. Int. Ed. 45, 1881\u20131886 (2006).","journal-title":"Angew. Chem. Int. Ed."},{"key":"1185_CR22","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/S0162-0134(98)10042-9","volume":"71","author":"L Rul\u00ed\u0161ek","year":"1998","unstructured":"Rul\u00ed\u0161ek, L. & Vondr\u00e1sek, J. Coordination geometries of selected transition metal ions (Co2+, Ni2+, Cu2+, Zn2+, Cd2+, and Hg2+) in metalloproteins. J. Inorg. Biochem. 71, 115\u2013127 (1998).","journal-title":"J. Inorg. Biochem."},{"key":"1185_CR23","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/0167-7799(94)90081-7","volume":"12","author":"FH Arnold","year":"1994","unstructured":"Arnold, F. H. & Zhang, J. H. Metal-mediated protein stabilization. Trends Biotechnol. 12, 189\u2013192 (1994).","journal-title":"Trends Biotechnol."},{"key":"1185_CR24","doi-asserted-by":"publisher","first-page":"2897","DOI":"10.1073\/pnas.1319866111","volume":"111","author":"JD Brodin","year":"2014","unstructured":"Brodin, J. D., Carr, J. R., Sontz, P. A. & Tezcan, F. A. Exceptionally stable, redox-active supramolecular protein assemblies with emergent properties. Proc. Natl Acad. Sci. USA 111, 2897\u20132902 (2014).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"1185_CR25","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1112\/jlms\/s1-40.1.577","volume":"s1-40","author":"B Gr\u00fcnbaum","year":"1965","unstructured":"Gr\u00fcnbaum, B. & Johnson, N. W. The faces of a regular-faced polyhedron. J. Lond. Math. Soc. s1-40, 577\u2013586 (1965).","journal-title":"J. Lond. Math. Soc."},{"key":"1185_CR26","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1038\/nature23320","volume":"548","author":"H Garcia-Seisdedos","year":"2017","unstructured":"Garcia-Seisdedos, H., Empereur-Mot, C., Elad, N. & Levy, E. D. Proteins evolve on the edge of supramolecular self-assembly. Nature 548, 244\u2013247 (2017).","journal-title":"Nature"},{"key":"1185_CR27","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14663","volume":"8","author":"E Sasaki","year":"2017","unstructured":"Sasaki, E. et al. Structure and assembly of scalable porous protein cages. Nat. Commun. 8, 14663 (2017).","journal-title":"Nat. Commun."},{"key":"1185_CR28","unstructured":"Huylebrouck, D. & Redondo, A. The Hendecagonal Stars in the Alhambra. In Proc. Bridges Finland 2016 (eds Torrence, E. et al.) 497\u2013500 (Tessellations, Phoenix, 2016)."},{"key":"1185_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1101\/SQB.1962.027.001.005","volume":"27","author":"DLD Caspar","year":"1962","unstructured":"Caspar, D. L. D. & Klug, A. Physical principles in the construction of regular viruses. Cold Spring Harb. Symp. Quant. Biol. 27, 1\u201324 (1962).","journal-title":"Cold Spring Harb. Symp. Quant. Biol."},{"key":"1185_CR30","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/978-1-4614-0980-9_3","volume":"726","author":"BV Prasad","year":"2012","unstructured":"Prasad, B. V. & Schmid, M. F. Principles of virus structural organization. Adv. Exp. Med. Biol. 726, 17\u201347 (2012).","journal-title":"Adv. Exp. Med. Biol."},{"key":"1185_CR31","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1021\/acsphotonics.6b00912","volume":"4","author":"D Cole","year":"2017","unstructured":"Cole, D., Young, G., Weigel, A., Sebesta, A. & Kukura, P. Label-free single-molecule imaging with numerical-aperture-shaped interferometric scattering microscopy. ACS Photonics 4, 211\u2013216 (2017).","journal-title":"ACS Photonics"},{"key":"1185_CR32","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1038\/nmeth.2472","volume":"10","author":"X Li","year":"2013","unstructured":"Li, X. et al. Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM. Nat. Methods 10, 584\u2013590 (2013).","journal-title":"Nat. Methods"},{"key":"1185_CR33","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1006\/jsbi.1996.0025","volume":"116","author":"T Yasunaga","year":"1996","unstructured":"Yasunaga, T. & Wakabayashi, T. Extensible and object-oriented system Eos supplies a new environment for image analysis of electron micrographs of macromolecules. J. Struct. Biol. 116, 155\u2013160 (1996).","journal-title":"J. Struct. Biol."},{"key":"1185_CR34","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.jsb.2006.05.009","volume":"157","author":"G Tang","year":"2007","unstructured":"Tang, G. et al. EMAN2: an extensible image processing suite for electron microscopy. J. Struct. Biol. 157, 38\u201346 (2007).","journal-title":"J. Struct. Biol."},{"key":"1185_CR35","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1006\/jsbi.1999.4174","volume":"128","author":"SJ Ludtke","year":"1999","unstructured":"Ludtke, S. J., Baldwin, P. R. & Chiu, W. EMAN: semiautomated software for high-resolution single-particle reconstructions. J. Struct. Biol. 128, 82\u201397 (1999).","journal-title":"J. Struct. Biol."},{"key":"1185_CR36","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1016\/j.jsb.2012.09.006","volume":"180","author":"SH Scheres","year":"2012","unstructured":"Scheres, S. H. RELION: implementation of a Bayesian approach to cryo-EM structure determination. J. Struct. Biol. 180, 519\u2013530 (2012).","journal-title":"J. Struct. Biol."},{"key":"1185_CR37","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1038\/nmeth.4193","volume":"14","author":"SQ Zheng","year":"2017","unstructured":"Zheng, S. Q. et al. MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy. Nat. Methods 14, 331\u2013332 (2017).","journal-title":"Nat. Methods"},{"key":"1185_CR38","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1006\/jsbi.2001.4339","volume":"133","author":"JB Heymann","year":"2001","unstructured":"Heymann, J. B. Bsoft: image and molecular processing in electron microscopy. J. Struct. Biol. 133, 156\u2013169 (2001).","journal-title":"J. Struct. Biol."},{"key":"1185_CR39","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.jsb.2015.08.008","volume":"192","author":"A Rohou","year":"2015","unstructured":"Rohou, A. & Grigorieff, N. CTFFIND4: Fast and accurate defocus estimation from electron micrographs. J. Struct. Biol. 192, 216\u2013221 (2015).","journal-title":"J. Struct. Biol."},{"key":"1185_CR40","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.jmb.2004.02.038","volume":"338","author":"NH Hopcroft","year":"2004","unstructured":"Hopcroft, N. H. et al. The interaction of RNA with TRAP: the role of triplet repeats and separating spacer nucleotides. J. Mol. Biol. 338, 43\u201353 (2004).","journal-title":"J. Mol. Biol."},{"key":"1185_CR41","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1038\/nmeth.2727","volume":"11","author":"A Kucukelbir","year":"2014","unstructured":"Kucukelbir, A., Sigworth, F. J. & Tagare, H. D. Quantifying the local resolution of cryo-EM density maps. Nat. Methods 11, 63\u201365 (2014).","journal-title":"Nat. Methods"},{"key":"1185_CR42","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.1002\/jcc.20084","volume":"25","author":"EF Pettersen","year":"2004","unstructured":"Pettersen, E. F. et al. UCSF Chimera\u2014a visualization system for exploratory research and analysis. J. Comput. Chem. 25, 1605\u20131612 (2004).","journal-title":"J. Comput. Chem."},{"key":"1185_CR43","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1107\/S0907444910007493","volume":"66","author":"P Emsley","year":"2010","unstructured":"Emsley, P., Lohkamp, B., Scott, W. G. & Cowtan, K. Features and development of Coot. Acta Crystallogr. D 66, 486\u2013501 (2010).","journal-title":"Acta Crystallogr. D"},{"key":"1185_CR44","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1042\/BJ20101813","volume":"434","author":"AD Malay","year":"2011","unstructured":"Malay, A. D., Watanabe, M., Heddle, J. G. & Tame, J. R. H. Crystal structure of unliganded TRAP: implications for dynamic allostery. Biochem. J. 434, 427\u2013434 (2011).","journal-title":"Biochem. J."},{"key":"1185_CR45","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1107\/S0907444909052925","volume":"66","author":"PD Adams","year":"2010","unstructured":"Adams, P. D. et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr. D 66, 213\u2013221 (2010).","journal-title":"Acta Crystallogr. D"},{"key":"1185_CR46","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms5808","volume":"5","author":"Z Wang","year":"2014","unstructured":"Wang, Z. et al. An atomic model of brome mosaic virus using direct electron detection and real-space optimization. Nat. Commun. 5, 4808 (2014).","journal-title":"Nat. Commun."},{"key":"1185_CR47","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1038\/nature24482","volume":"551","author":"SK Natchiar","year":"2017","unstructured":"Natchiar, S. K., Myasnikov, A. G., Kratzat, H., Hazemann, I. & Klaholz, B. P. Visualization of chemical modifications in the human 80S ribosome structure. Nature 551, 472\u2013477 (2017).","journal-title":"Nature"},{"key":"1185_CR48","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1107\/S0907444909042073","volume":"66","author":"VB Chen","year":"2010","unstructured":"Chen, V. B. et al. MolProbity: all-atom structure validation for macromolecular crystallography. Acta Crystallogr. D 66, 12\u201321 (2010).","journal-title":"Acta Crystallogr. D"},{"key":"1185_CR49","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1016\/j.jmb.2007.05.022","volume":"372","author":"E Krissinel","year":"2007","unstructured":"Krissinel, E. & Henrick, K. Inference of macromolecular assemblies from crystalline state. J. Mol. Biol. 372, 774\u2013797 (2007).","journal-title":"J. Mol. Biol."},{"key":"1185_CR50","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/j.nimb.2014.02.067","volume":"332","author":"P Pelicon","year":"2014","unstructured":"Pelicon, P. et al. A high brightness proton injector for the Tandetron accelerator at Jo\u017eef Stefan Institute. Nucl. Instrum. Methods Phys. Res. B 332, 229\u2013233 (2014).","journal-title":"Nucl. Instrum. Methods Phys. Res. B"},{"key":"1185_CR51","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.nimb.2017.01.023","volume":"404","author":"P Vavpeti\u010d","year":"2017","unstructured":"Vavpeti\u010d, P., Kelemen, M., Jen\u010di\u010d, B. & Pelicon, P. Nuclear microprobe performance in high-current proton beam mode for micro-PIXE. Nucl. Instrum. Methods Phys. Res. B 404, 69\u201373 (2017).","journal-title":"Nucl. Instrum. Methods Phys. Res. B"},{"key":"1185_CR52","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1016\/j.nimb.2004.01.201","volume":"219\u2013220","author":"J Pallon","year":"2004","unstructured":"Pallon, J. et al. An off-axis STIM procedure for precise mass determination and imaging. Nucl. Instrum. Methods Phys. Res. B 219\u2013220, 988\u2013993 (2004).","journal-title":"Nucl. Instrum. Methods Phys. Res. B"},{"key":"1185_CR53","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.pbiomolbio.2004.09.005","volume":"89","author":"EF Garman","year":"2005","unstructured":"Garman, E. F. & Grime, G. W. Elemental analysis of proteins by microPIXE. Prog. Biophys. Mol. Biol. 89, 173\u2013205 (2005).","journal-title":"Prog. Biophys. Mol. Biol."},{"key":"1185_CR54","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/S0168-583X(00)00156-7","volume":"170","author":"JL Campbell","year":"2000","unstructured":"Campbell, J. L., Hopman, T. L., Maxwell, J. A. & Nejedly, Z. The Guelph PIXE software package III: alternative proton database. Nucl. Instrum. Methods Phys. Res. B 170, 193\u2013204 (2000).","journal-title":"Nucl. Instrum. Methods Phys. Res. B"},{"key":"1185_CR55","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1007\/978-1-4939-2230-7_18","volume":"1261","author":"FD Kondrat","year":"2015","unstructured":"Kondrat, F. D., Struwe, W. B. & Benesch, J. L. Native mass spectrometry: towards high-throughput structural proteomics. Methods Mol. Biol. 1261, 349\u2013371 (2015).","journal-title":"Methods Mol. Biol."},{"key":"1185_CR56","doi-asserted-by":"publisher","first-page":"1402","DOI":"10.1021\/ac0110552","volume":"74","author":"F Sobott","year":"2002","unstructured":"Sobott, F., Hern\u00e1ndez, H., McCammon, M. G., Tito, M. A. & Robinson, C. V. A tandem mass spectrometer for improved transmission and analysis of large macromolecular assemblies. Anal. Chem. 74, 1402\u20131407 (2002).","journal-title":"Anal. Chem."},{"key":"1185_CR57","unstructured":"Press, W. H., Teukolsky, S. A., Vetterling, W. T. & Flannery, B. P. Numerical recipes in C: the art of scientific computing\u00a02nd edn (Cambridge Univ. Press, Cambridge, 1992)."},{"key":"1185_CR58","doi-asserted-by":"publisher","first-page":"214703","DOI":"10.1063\/1.3268782","volume":"131","author":"GA Simms","year":"2009","unstructured":"Simms, G. A., Padmos, J. D. & Zhang, P. Structural and electronic properties of protein\/thiolate-protected gold nanocluster with \u201cstaple\u201d motif: A XAS, L-DOS, and XPS study. J. Chem. Phys. 131, 214703 (2009).","journal-title":"J. Chem. Phys."},{"key":"1185_CR59","doi-asserted-by":"publisher","first-page":"245502","DOI":"10.1103\/PhysRevLett.90.245502","volume":"90","author":"P Zhang","year":"2003","unstructured":"Zhang, P. & Sham, T. K. X-ray studies of the structure and electronic behavior of alkanethiolate-capped gold nanoparticles: the interplay of size and surface effects. Phys. Rev. Lett. 90, 245502 (2003).","journal-title":"Phys. Rev. Lett."},{"key":"1185_CR60","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1080\/05704920701551530","volume":"42","author":"Z Movasaghi","year":"2007","unstructured":"Movasaghi, Z., Rehman, S. & Rehman, I. U. Raman spectroscopy of biological tissues. Appl. Spectrosc. Rev. 42, 493\u2013541 (2007).","journal-title":"Appl. Spectrosc. Rev."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41586-019-1185-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41586-019-1185-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41586-019-1185-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T03:15:21Z","timestamp":1732763721000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41586-019-1185-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,8]]},"references-count":60,"journal-issue":{"issue":"7756","published-print":{"date-parts":[[2019,5,16]]}},"alternative-id":["1185"],"URL":"https:\/\/doi.org\/10.1038\/s41586-019-1185-4","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,8]]},"assertion":[{"value":"4 June 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 May 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A.D.M. and J.G.H. are named as inventors on a patent application related to the use of gold to cross-link cysteine residues aimed at protein assembly construction.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}