{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T19:55:03Z","timestamp":1773086103815,"version":"3.50.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T00:00:00Z","timestamp":1590019200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T00:00:00Z","timestamp":1590019200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100005713","name":"United States Department of Defense | Office of the Secretary of Defense","doi-asserted-by":"publisher","award":["W81XWH-14-1-0042"],"award-info":[{"award-number":["W81XWH-14-1-0042"]}],"id":[{"id":"10.13039\/100005713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005713","name":"United States Department of Defense | Office of the Secretary of Defense","doi-asserted-by":"publisher","award":["W81XWH-14-1-0042"],"award-info":[{"award-number":["W81XWH-14-1-0042"]}],"id":[{"id":"10.13039\/100005713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005713","name":"United States Department of Defense | Office of the Secretary of Defense","doi-asserted-by":"publisher","award":["W81XWH-14-1-0042"],"award-info":[{"award-number":["W81XWH-14-1-0042"]}],"id":[{"id":"10.13039\/100005713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005713","name":"United States Department of Defense | Office of the Secretary of Defense","doi-asserted-by":"publisher","award":["W81XWH-14-1-0042"],"award-info":[{"award-number":["W81XWH-14-1-0042"]}],"id":[{"id":"10.13039\/100005713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005713","name":"United States Department of Defense | Office of the Secretary of Defense","doi-asserted-by":"publisher","award":["W81XWH-14-1-0042"],"award-info":[{"award-number":["W81XWH-14-1-0042"]}],"id":[{"id":"10.13039\/100005713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005713","name":"United States Department of Defense | Office of the Secretary of Defense","doi-asserted-by":"publisher","award":["W81XWH-14-1-0042"],"award-info":[{"award-number":["W81XWH-14-1-0042"]}],"id":[{"id":"10.13039\/100005713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005713","name":"United States Department of Defense | Office of the Secretary of Defense","doi-asserted-by":"publisher","award":["W81XWH-14-1-0042"],"award-info":[{"award-number":["W81XWH-14-1-0042"]}],"id":[{"id":"10.13039\/100005713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005713","name":"United States Department of Defense | Office of the Secretary of Defense","doi-asserted-by":"publisher","award":["W81XWH-14-1-0042"],"award-info":[{"award-number":["W81XWH-14-1-0042"]}],"id":[{"id":"10.13039\/100005713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005713","name":"United States Department of Defense | Office of the Secretary of Defense","doi-asserted-by":"publisher","award":["W81XWH-14-1-0042"],"award-info":[{"award-number":["W81XWH-14-1-0042"]}],"id":[{"id":"10.13039\/100005713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005713","name":"United States Department of Defense | Office of the Secretary of Defense","doi-asserted-by":"publisher","award":["W81XWH-14-1-0042"],"award-info":[{"award-number":["W81XWH-14-1-0042"]}],"id":[{"id":"10.13039\/100005713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005713","name":"United States Department of Defense | Office of the Secretary of Defense","doi-asserted-by":"publisher","award":["W81XWH-14-1-0042"],"award-info":[{"award-number":["W81XWH-14-1-0042"]}],"id":[{"id":"10.13039\/100005713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["DGE-1333468"],"award-info":[{"award-number":["DGE-1333468"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["npj Digit. Med."],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Telementoring platforms can help transfer surgical expertise remotely. However, most telementoring platforms are not designed to assist in austere, pre-hospital settings. This paper evaluates the system for telementoring with augmented reality (STAR), a portable and self-contained telementoring platform based on an augmented reality head-mounted display (ARHMD). The system is designed to assist in austere scenarios: a stabilized first-person view of the operating field is sent to a remote expert, who creates surgical instructions that a local first responder wearing the ARHMD can visualize as three-dimensional models projected onto the patient\u2019s body. Our hypothesis evaluated whether remote guidance with STAR could lead to performing a surgical procedure better, as opposed to remote audio-only guidance. Remote expert surgeons guided first responders through training cricothyroidotomies in a simulated austere scenario, and on-site surgeons evaluated the participants using standardized evaluation tools. The evaluation comprehended completion time and technique performance of specific cricothyroidotomy steps. The analyses were also performed considering the participants\u2019 years of experience as first responders, and their experience performing cricothyroidotomies. A linear mixed model analysis showed that using STAR was associated with higher procedural and non-procedural scores, and overall better performance. Additionally, a binary logistic regression analysis showed that using STAR was associated to safer and more successful executions of cricothyroidotomies. This work demonstrates that remote mentors can use STAR to provide first responders with guidance and surgical knowledge, and represents a first step towards the adoption of ARHMDs to convey clinical expertise remotely in austere scenarios.<\/jats:p>","DOI":"10.1038\/s41746-020-0284-9","type":"journal-article","created":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T10:02:26Z","timestamp":1590055346000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Evaluation of an augmented reality platform for austere surgical telementoring: a randomized controlled crossover study in cricothyroidotomies"],"prefix":"10.1038","volume":"3","author":[{"given":"Edgar","family":"Rojas-Mu\u00f1oz","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5768-9000","authenticated-orcid":false,"given":"Chengyuan","family":"Lin","sequence":"additional","affiliation":[]},{"given":"Natalia","family":"Sanchez-Tamayo","sequence":"additional","affiliation":[]},{"given":"Maria Eugenia","family":"Cabrera","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5640-1845","authenticated-orcid":false,"given":"Daniel","family":"Andersen","sequence":"additional","affiliation":[]},{"given":"Voicu","family":"Popescu","sequence":"additional","affiliation":[]},{"given":"Juan Antonio","family":"Barragan","sequence":"additional","affiliation":[]},{"given":"Ben","family":"Zarzaur","sequence":"additional","affiliation":[]},{"given":"Patrick","family":"Murphy","sequence":"additional","affiliation":[]},{"given":"Kathryn","family":"Anderson","sequence":"additional","affiliation":[]},{"given":"Thomas","family":"Douglas","sequence":"additional","affiliation":[]},{"given":"Clare","family":"Griffis","sequence":"additional","affiliation":[]},{"given":"Jessica","family":"McKee","sequence":"additional","affiliation":[]},{"given":"Andrew W.","family":"Kirkpatrick","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6425-5745","authenticated-orcid":false,"given":"Juan P.","family":"Wachs","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2020,5,21]]},"reference":[{"key":"284_CR1","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1001\/jamasurg.2015.3104","volume":"151","author":"RS Kotwal","year":"2016","unstructured":"Kotwal, R. S. et al. The effect of a golden hour policy on the morbidity and mortality of combat casualties. JAMA Surg. 151, 15\u201324 (2016).","journal-title":"JAMA Surg."},{"key":"284_CR2","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1097\/SLA.0b013e31827eefcf","volume":"257","author":"JJ Morrison","year":"2013","unstructured":"Morrison, J. J. et al. En-route care capability from point of injury impacts mortality after severe wartime injury. Ann. Surg. 257, 330\u2013334 (2013).","journal-title":"Ann. Surg."},{"key":"284_CR3","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1097\/01.sla.0000220038.66466.b5","volume":"243","author":"BA Pruitt Jr.","year":"2006","unstructured":"Pruitt, B. A. Jr. Combat casualty care and surgical progress. Ann. Surg. 243, 715\u2013729 (2006).","journal-title":"Ann. Surg."},{"key":"284_CR4","unstructured":"Office of the Press Secretary. HSPD-8, Homeland Security Presidential Directive. https:\/\/fas.org\/irp\/offdocs\/nspd\/hspd-8.html (2003)."},{"key":"284_CR5","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1111\/j.1553-2712.2001.tb00201.x","volume":"8","author":"EB Lerner","year":"2001","unstructured":"Lerner, E. B. & Moscati, R. M. The golden hour: scientific fact or medical \u2018urban legend\u2019? Acad. Emerg. Med. 8, 758\u2013760 (2001).","journal-title":"Acad. Emerg. Med."},{"key":"284_CR6","first-page":"80","volume":"2015","author":"T Rasmussen","year":"2015","unstructured":"Rasmussen, T., Baer, D., Doll, B. & Caravalho, J. In the golden hour. Army ALT Mag. 2015, 80\u201385 (2015).","journal-title":"Army ALT Mag."},{"key":"284_CR7","doi-asserted-by":"publisher","first-page":"2754","DOI":"10.1245\/s10434-013-2894-9","volume":"20","author":"S Treter","year":"2013","unstructured":"Treter, S., Perrier, N., Sosa, J. A. & Roman, S. Telementoring: a multi-institutional experience with the introduction of a novel surgical approach for adrenalectomy. Ann. Surg. Oncol. 20, 2754\u20132758 (2013).","journal-title":"Ann. Surg. Oncol."},{"key":"284_CR8","doi-asserted-by":"publisher","first-page":"1334","DOI":"10.1002\/lary.25753","volume":"126","author":"CH Snyderman","year":"2016","unstructured":"Snyderman, C. H., Gardner, P. A., Lanisnik, B. & Ravnik, J. Surgical telementoring: s new model for surgical training. Laryngoscope 126, 1334\u20131338 (2016).","journal-title":"Laryngoscope"},{"key":"284_CR9","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1007\/s003450050082","volume":"16","author":"BR Lee","year":"1998","unstructured":"Lee, B. R. et al. A novel method of surgical instruction: international telementoring. World J. Urol. 16, 367\u2013370 (1998).","journal-title":"World J. Urol."},{"key":"284_CR10","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1097\/TA.0000000000000829","volume":"79","author":"AW Kirkpatrick","year":"2015","unstructured":"Kirkpatrick, A. W. et al. The marriage of surgical simulation and telementoring for damage-control surgical training of operational first responders: a pilot study. J. Trauma Acute Care Surg. 79, 741\u2013747 (2015).","journal-title":"J. Trauma Acute Care Surg."},{"key":"284_CR11","doi-asserted-by":"publisher","first-page":"S85","DOI":"10.1503\/cjs.013914","volume":"58","author":"MAW Kirkpatrick","year":"2015","unstructured":"Kirkpatrick, M. A. W. et al. The need for a robust 24\/7 subspecialty \u2018clearing house\u2019 response for telementored trauma care. Can. J. Surg. 58, S85\u2013S87 (2015).","journal-title":"Can. J. Surg."},{"key":"284_CR12","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1097\/TA.0b013e3181878052","volume":"65","author":"D Dyer","year":"2008","unstructured":"Dyer, D. et al. The clinical and technical evaluation of a remote telementored telesonography system during the acute resuscitation and transfer of the injured patient. J. Trauma Acute Care Surg. 65, 1209\u20131216 (2008).","journal-title":"J. Trauma Acute Care Surg."},{"key":"284_CR13","doi-asserted-by":"publisher","first-page":"S156","DOI":"10.1097\/TA.0000000000001483","volume":"83","author":"AW Kirkpatrick","year":"2017","unstructured":"Kirkpatrick, A. W. et al. The Damage Control Surgery in Austere Environments Research Group (DCSAERG): a dynamic program to facilitate real-time telementoring\/telediagnosis to address exsanguination in extreme and austere environments. J. Trauma Acute Care Surg. 83, S156\u2013S163 (2017).","journal-title":"J. Trauma Acute Care Surg."},{"key":"284_CR14","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1016\/j.amjsurg.2018.01.016","volume":"215","author":"P Dawe","year":"2018","unstructured":"Dawe, P. et al. Tele-mentored damage-control and emergency trauma surgery: a feasibility study using live-tissue models. Am. J. Surg. 215, 927\u2013929 (2018).","journal-title":"Am. J. Surg."},{"key":"284_CR15","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1089\/tmj.2018.0173","volume":"25","author":"I Netzer","year":"2019","unstructured":"Netzer, I. et al. Rubrum Coelis: the contribution of real-time telementoring in acute trauma scenarios: a randomized controlled trial. Telemed. E-Health 25, 1108\u20131114 (2019).","journal-title":"Telemed. E-Health"},{"key":"284_CR16","doi-asserted-by":"publisher","first-page":"e14","DOI":"10.2196\/ijmr.2611","volume":"2","author":"A Budrionis","year":"2013","unstructured":"Budrionis, A., Augestad, K. M., Patel, H. R. & Bellika, J. G. An evaluation framework for defining the contributions of telestration in surgical telementoring. Interact. J. Med. Res. 2, e14 (2013).","journal-title":"Interact. J. Med. Res."},{"key":"284_CR17","doi-asserted-by":"crossref","unstructured":"Patrick, E. et al. Using a large projection screen as an alternative to head-mounted displays for virtual environments. In Proceedings of the SIGCHI conference on Human Factors in Computing Systems 478\u2013485 (ACM, The Hague, The Netherlands, 2000).","DOI":"10.1145\/332040.332479"},{"key":"284_CR18","unstructured":"Downs, R. M. & Stea, D. Image and Environment: Cognitive Mapping and Spatial Behavior (Transaction Publishers, 1974)."},{"key":"284_CR19","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1136\/jramc-2017-000817","volume":"164","author":"M Talbot","year":"2018","unstructured":"Talbot, M. et al. A pilot study of surgical telementoring for leg fasciotomy. J. R. Army Med. Corps 164, 83\u201386 (2018).","journal-title":"J. R. Army Med. Corps"},{"key":"284_CR20","doi-asserted-by":"publisher","first-page":"1646","DOI":"10.1016\/j.surg.2015.12.016","volume":"159","author":"D Andersen","year":"2016","unstructured":"Andersen, D. et al. Medical telementoring using an augmented reality transparent display. Surgery 159, 1646\u20131653 (2016).","journal-title":"Surgery"},{"key":"284_CR21","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1001\/archsurg.139.2.170","volume":"139","author":"JH Shuhaiber","year":"2004","unstructured":"Shuhaiber, J. H. Augmented reality in surgery. Arch. Surg. 139, 170\u2013174 (2004).","journal-title":"Arch. Surg."},{"key":"284_CR22","doi-asserted-by":"crossref","unstructured":"Bossi, L. L., Jones, M. L., Kelly, A. & Tack, D. W. A Preliminary investigation of the effect of protective clothing weight, bulk and stiffness on combat mobility course performance. In Proceedings of the Human Factors and Ergonomics Society Annual Meeting Vol. 60, 702\u2013706 (SAGE Publications, Washington, DC, USA, 2016).","DOI":"10.1177\/1541931213601161"},{"key":"284_CR23","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1097\/SLA.0000000000002764","volume":"270","author":"E Rojas-Mu\u00f1oz","year":"2018","unstructured":"Rojas-Mu\u00f1oz, E. et al. Surgical telementoring without encumbrance: a comparative study of see-through augmented reality-based approaches. Ann. Surg. 270, 384\u2013389 (2018).","journal-title":"Ann. Surg."},{"key":"284_CR24","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1016\/j.intcom.2008.04.003","volume":"20","author":"J-M Luursema","year":"2008","unstructured":"Luursema, J.-M., Verwey, W. B., Kommers, P. A. & Annema, J. H. The role of stereopsis in virtual anatomical learning. Interact. Comput. 20, 455\u2013460 (2008).","journal-title":"Interact. Comput."},{"key":"284_CR25","unstructured":"Johnson, D. M. Introduction to and Review of Simulator Sickness Research. Army Research Institute Field Unit Fort Rucker Al (Army Research Institute Field Unit, Fort Rucker Al, 2005)."},{"key":"284_CR26","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1177\/1553350618813250","volume":"26","author":"S Erridge","year":"2019","unstructured":"Erridge, S., Yeung, D. K., Patel, H. R. & Purkayastha, S. Telementoring of surgeons: a systematic review. Surg. Innov. 26, 95\u2013111 (2019).","journal-title":"Surg. Innov."},{"key":"284_CR27","doi-asserted-by":"crossref","unstructured":"Butler, F. Tactical Combat Casualty Care: Combining Good Medicine with Good Tactics. 54, S2\u2013S3 (LWW, 2003).","DOI":"10.1097\/01.TA.0000064504.55800.73"},{"key":"284_CR28","doi-asserted-by":"crossref","unstructured":"Bertasius, G., Soo Park, H., Yu, S. X. & Shi, J. Am I a baller? Basketball performance assessment from first-person videos. In Proceedings of the IEEE International Conference on Computer Vision 2177\u20132185 (Venice, Italy, 2017).","DOI":"10.1109\/ICCV.2017.239"},{"key":"284_CR29","doi-asserted-by":"crossref","first-page":"11","DOI":"10.55460\/KYGI-F0VF","volume":"15","author":"R Mabry","year":"2015","unstructured":"Mabry, R., Frankfurt, A., Kharod, C. & Butler, F. Emergency cricothyroidotomy in tactical combat casualty care. J. Spec. Oper. Med 15, 11\u201319 (2015).","journal-title":"J. Spec. Oper. Med"},{"key":"284_CR30","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.jss.2018.09.015","volume":"235","author":"JL Green","year":"2019","unstructured":"Green, J. L. et al. The utilization of video technology in surgical education: a systematic review. J. Surg. Res. 235, 171\u2013180 (2019).","journal-title":"J. Surg. Res."},{"key":"284_CR31","unstructured":"Ryan, K. L. et al. Advanced technology development for remote triage applications in bleeding combat casualties. US Army Med. Dep. J. 61\u201371 (2011)."},{"key":"284_CR32","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1109\/TBME.2019.2914517","volume":"67","author":"S Condino","year":"2019","unstructured":"Condino, S., Carbone, M., Piazza, R., Ferrari, M. & Ferrari, V. Perceptual limits of optical see-through visors for augmented reality guidance of manual tasks. IEEE Trans. Biomed. Eng. 67, 411\u2013419 (2019).","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"284_CR33","doi-asserted-by":"crossref","unstructured":"Pan, S., Atalla, M. A. & Kavoussi, L. R. Telementoring. New Technologies in Urology 251\u2013257 (Springer, 2010).","DOI":"10.1007\/978-1-84882-178-1_28"},{"key":"284_CR34","doi-asserted-by":"crossref","unstructured":"Lin, C. et al. How about the mentor? Effective Workspace Visualization in AR Telementoring. In Virtual Reality and 3D User Interfaces 2020 IEEE Conference (IEEE, USA, 2020).","DOI":"10.1109\/VR46266.2020.00040"},{"key":"284_CR35","doi-asserted-by":"crossref","unstructured":"Lin, C. et al. A first-person mentee second-person mentor AR interface for surgical telementoring. In Mixed and Augmented Reality, 2018 IEEE International Symposium, 3\u20138 (IEEE, Munich, Germany, 2018).","DOI":"10.1109\/ISMAR-Adjunct.2018.00021"},{"key":"284_CR36","unstructured":"United States Army Training and Doctrine Command DA FORM 7595-2-10. Perform a Surgical Cricothyroidotomy. In TC 8-800 MEdical Education and Demonstration of Individual Competence (Army Publishing Directorate, 2014)."},{"key":"284_CR37","unstructured":"Center for Army Lessons Learned. Tactical Combat Casualty Care Handbook. Vol. 5 (United States Army, 2017)."},{"key":"284_CR38","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1177\/0194599814556722","volume":"152","author":"J Melchiors","year":"2015","unstructured":"Melchiors, J. et al. Preparing for emergency: a valid, reliable assessment tool for emergency cricothyroidotomy skills. Otolaryngol. Neck Surg. 152, 260\u2013265 (2015).","journal-title":"Otolaryngol. Neck Surg."},{"key":"284_CR39","doi-asserted-by":"publisher","first-page":"1663","DOI":"10.1213\/ane.0b013e3181841efe","volume":"107","author":"Z Friedman","year":"2008","unstructured":"Friedman, Z., You-Ten, K. E., Bould, M. D. & Naik, V. Teaching lifesaving procedures: the impact of model fidelity on acquisition and transfer of cricothyrotomy skills to performance on cadavers. Anesth. Analg. 107, 1663\u20131669 (2008).","journal-title":"Anesth. Analg."},{"key":"284_CR40","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1093\/biomet\/52.3-4.591","volume":"52","author":"SS Shapiro","year":"1965","unstructured":"Shapiro, S. S. & Wilk, M. B. An analysis of variance test for normality (complete samples). Biometrika 52, 591\u2013611 (1965).","journal-title":"Biometrika"},{"key":"284_CR41","unstructured":"Levene, H. Robust tests for equality of variances. In Contributions to probability and statistics: essays in honor of Harold Hotelling. 279\u2013292 (Stanford University Press, 1960)."},{"key":"284_CR42","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1214\/ss\/1177011926","volume":"6","author":"GK Robinson","year":"1991","unstructured":"Robinson, G. K. et al. That BLUP is a good thing: the estimation of random effects. Stat. Sci. 6, 15\u201332 (1991).","journal-title":"Stat. Sci."},{"key":"284_CR43","unstructured":"Cramer, J. S. The Origins of Logistic Regression. Tinbergen Institute Working Paper No. 2002-119\/4 (2002)."},{"key":"284_CR44","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1093\/biomet\/54.1-2.167","volume":"54","author":"SH Walker","year":"1967","unstructured":"Walker, S. H. & Duncan, D. B. Estimation of the probability of an event as a function of several independent variables. Biometrika 54, 167\u2013179 (1967).","journal-title":"Biometrika"}],"container-title":["npj Digital Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41746-020-0284-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41746-020-0284-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41746-020-0284-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T02:16:22Z","timestamp":1670379382000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41746-020-0284-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,21]]},"references-count":44,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,12]]}},"alternative-id":["284"],"URL":"https:\/\/doi.org\/10.1038\/s41746-020-0284-9","relation":{},"ISSN":["2398-6352"],"issn-type":[{"value":"2398-6352","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,21]]},"assertion":[{"value":"9 July 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 May 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"V.P. and J.P.W. are inventors on a US issued patent, submitted by Purdue Research Foundation, which is relevant to this work. E.R.-M., C.L., N.S.-T., M.E.C., D.A., V.P., B.Z., P.M., K.A., C.D.R.T.D., and J.P.W. received funding from the grant reported in the Acknowledgements section.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"75"}}