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Med."],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Wrist-worn devices with heart rate monitoring have become increasingly popular. Although current guidelines advise to consider clinical symptoms and exercise tolerance during decision-making in heart disease, it remains unknown to which extent wearables can help to determine such functional capacity measures. In clinical settings, the 6-minute walk test has become a standardized diagnostic and prognostic marker. We aimed to explore, whether 6-minute walk distances can be predicted by wrist-worn devices in patients with different stages of mitral and aortic valve disease. A total of <jats:italic>n<\/jats:italic>\u2009=\u2009107 sensor datasets with 1,019,748\u2009min of recordings were analysed. Based on heart rate recordings and literature information, activity levels were determined and compared to results from a 6-minute walk test. The percentage of time spent in moderate activity was a predictor for the achievement of gender, age and body mass index-specific 6-minute walk distances (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001; <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.48). The uncertainty of these predictions is demonstrated.<\/jats:p>","DOI":"10.1038\/s41746-020-0299-2","type":"journal-article","created":{"date-parts":[[2020,7,9]],"date-time":"2020-07-09T10:06:38Z","timestamp":1594289198000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Wearable devices can predict the outcome of standardized 6-minute walk tests in heart disease"],"prefix":"10.1038","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2885-8055","authenticated-orcid":false,"given":"Charlotte","family":"Schubert","sequence":"first","affiliation":[]},{"given":"Gareth","family":"Archer","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2110-4901","authenticated-orcid":false,"given":"Jo M.","family":"Zelis","sequence":"additional","affiliation":[]},{"given":"Sarah","family":"Nordmeyer","sequence":"additional","affiliation":[]},{"given":"Kilian","family":"Runte","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0737-7375","authenticated-orcid":false,"given":"Anja","family":"Hennemuth","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7881-1557","authenticated-orcid":false,"given":"Felix","family":"Berger","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7911-8620","authenticated-orcid":false,"given":"Volkmar","family":"Falk","sequence":"additional","affiliation":[]},{"given":"Pim A. 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