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Med."],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>My Kidneys &amp; Me (MK&amp;M), a digital health intervention delivering specialist health and lifestyle education for people with CKD, was developed and its effects tested (SMILE-K trial, ISRCTN18314195, 18\/12\/2020). 420 adult patients with CKD stages 3\u20134 were recruited and randomised 2:1 to intervention (MK&amp;M) (<jats:italic>n<\/jats:italic>\u2009=\u2009280) or control (<jats:italic>n<\/jats:italic>\u2009=\u2009140) groups. Outcomes, including Patient Activation Measure (PAM-13), were collected at baseline and 20 weeks. Complete case (CC) and per-protocol (PP) analyses were conducted. 210 (75%) participants used MK&amp;M more than once. PAM-13 increased at 20 weeks compared to control (CC: +3.1 (95%CI: \u22120.2 to 6.4), <jats:italic>P<\/jats:italic>\u2009=\u20090.065; PP: +3.6 (95%CI: 0.2 to 7.0), <jats:italic>P<\/jats:italic>\u2009=\u20090.041). In those with low activation at baseline, significant between-group differences were observed (CC: +6.6 (95%CI: 1.3 to 11.9), <jats:italic>P<\/jats:italic>\u2009=\u20090.016; PP: +9.2 (95%CI: 4.0 to 14.6), <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) favouring MK&amp;M group. MK&amp;M improved patient activation in those who used the resource compared to standard care, although the overall effect was non-significant. The greatest benefits were seen in those with low activation.<\/jats:p>","DOI":"10.1038\/s41746-024-01296-1","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T07:54:42Z","timestamp":1731398082000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["The effects of a digital health intervention on patient activation in chronic kidney disease"],"prefix":"10.1038","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5855-4159","authenticated-orcid":false,"given":"Courtney J.","family":"Lightfoot","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas J.","family":"Wilkinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gurneet K.","family":"Sohansoha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clare L.","family":"Gillies","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noemi","family":"Vadaszy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ella C.","family":"Ford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9987-9371","authenticated-orcid":false,"given":"Melanie J.","family":"Davies","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Yates","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice C.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew P. 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