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Interventions facilitated early intervention to prevent condition worsening (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20094); self-management (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20092); and patient-initiated care (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20091). Intervention costs were estimated by top-down costing (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20092); bottom-up micro-costing (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20093) and assumptions (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20092). Mobile device-based active remote monitoring was cost-effective in six of the seven studies with a high degree of decision uncertainty. The results will help decision-makers, intervention developers and analysts to guide resource allocation, product development and study designs for future mobile device-based monitoring interventions, respectively.\n                  <\/jats:p>","DOI":"10.1038\/s41746-025-01898-3","type":"journal-article","created":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T15:28:34Z","timestamp":1761319714000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Active remote monitoring of long-term conditions with mobile devices: a systematic review of cost-effectiveness analyses"],"prefix":"10.1038","volume":"8","author":[{"given":"Sean P.","family":"Gavan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Payne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William G.","family":"Dixon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine N.","family":"van der Veer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander C. 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