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Alfredo Cesario serves as Chief Executive Officer of Gemelli Digital Medicine & Health and Digital Health Manager at Fondazione Policlinico Gemelli IRCCS. Federico Chinni is General Manager of UCB Italy and co-coordinator of the Digital & Connected HealthCare Group at Farmindustria. These affiliations are reported for transparency only and had no influence on the content of this work.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"226"}}