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R.A.d.B.: has had speaker engagements with and\/or received fees from and\/or served on an advisory board for Abbott, AstraZeneca, Bristol Myers Squibb, NovoNordisk, Roche, and Zoll and received travel support from Abbott and NovoNordisk. R.M.A.v.d.B.: reports an independent research grant paid to the Institute from Abbott for IIS and has had speaker engagement in the past 5 years with Abbott, AstraZeneca, and Novartis. J.J.B:. reports an independent research grant paid to the Institute from Abbott for IIS and has had speaker engagement or advisory boards in the past 5 years with: AstraZeneca, Abbott, Boehringer-Ingelheim, Bayer, Daiichi Sankyo, Novartis and Vifor. All other authors declared to have no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"234"}}