{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T12:20:49Z","timestamp":1777983649675,"version":"3.51.4"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:00:00Z","timestamp":1777939200000},"content-version":"vor","delay-in-days":49,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/100008710","name":"Dementia Australia Research Foundation","doi-asserted-by":"publisher","award":["Henry Brodaty Mid-Career Fellowship"],"award-info":[{"award-number":["Henry Brodaty Mid-Career Fellowship"]}],"id":[{"id":"10.13039\/100008710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009727","name":"Hospital Research Foundation","doi-asserted-by":"publisher","award":["C-PJ-008-Transl-2020"],"award-info":[{"award-number":["C-PJ-008-Transl-2020"]}],"id":[{"id":"10.13039\/100009727","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009727","name":"Hospital Research Foundation","doi-asserted-by":"publisher","award":["C-PJ-008-Transl-2020"],"award-info":[{"award-number":["C-PJ-008-Transl-2020"]}],"id":[{"id":"10.13039\/100009727","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","award":["Discovery Early Career Award (DECRA; DE230101174)"],"award-info":[{"award-number":["Discovery Early Career Award (DECRA; DE230101174)"]}],"id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["npj Digit. Med."],"DOI":"10.1038\/s41746-026-02542-4","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T09:31:31Z","timestamp":1773739891000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["An interactive tool to personalise 24-hour activity, sitting and sleep prescription for optimal health outcomes"],"prefix":"10.1038","volume":"9","author":[{"given":"Maddison L.","family":"Mellow","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tyman E.","family":"Stanford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy","family":"Olds","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron","family":"Miatke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashleigh E.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorothea","family":"Dumuid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,17]]},"reference":[{"key":"2542_CR1","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1016\/j.nbt.2012.03.009","volume":"29","author":"A Harvey","year":"2012","unstructured":"Harvey, A. et al. The future of technologies for personalised medicine. N. Biotechnol. 29, 625\u2013633 (2012).","journal-title":"N. Biotechnol."},{"key":"2542_CR2","doi-asserted-by":"publisher","DOI":"10.1186\/s40798-021-00394-8","volume":"7","author":"A Holtermann","year":"2021","unstructured":"Holtermann, A. et al. 24-Hour physical behavior balance for better health for all: \u201cthe sweet-spot hypothesis\u201d. Sports Med. - Open 7, 98 (2021).","journal-title":"Sports Med. - Open"},{"key":"2542_CR3","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1136\/jech-2021-216686","volume":"76","author":"D Dumuid","year":"2022","unstructured":"Dumuid, D. et al. Goldilocks Days: optimising children\u2019s time use for health and well-being. J. Epidemiol. Community Health 76, 301 (2022).","journal-title":"J. Epidemiol. Community Health"},{"key":"2542_CR4","doi-asserted-by":"publisher","first-page":"e0272343","DOI":"10.1371\/journal.pone.0272343","volume":"17","author":"D Dumuid","year":"2022","unstructured":"Dumuid, D. et al. Your best day: An interactive app to translate how time reallocations within a 24-hour day are associated with health measures. PLoS ONE 17, e0272343 (2022).","journal-title":"PLoS ONE"},{"key":"2542_CR5","doi-asserted-by":"publisher","first-page":"4034","DOI":"10.1093\/eurheartj\/ehaa691","volume":"41","author":"A Sommerlad","year":"2020","unstructured":"Sommerlad, A. & Mukadam, N. Evaluating risk of dementia in older people: a pathway to personalized prevention? Eur. Heart J. 41, 4034\u20134036 (2020).","journal-title":"Eur. Heart J."},{"key":"2542_CR6","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/S0140-6736(24)01296-0","volume":"404","author":"G Livingston","year":"2024","unstructured":"Livingston, G. et al. Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission. Lancet 404, 572\u2013628 (2024).","journal-title":"Lancet"},{"key":"2542_CR7","doi-asserted-by":"publisher","first-page":"2393","DOI":"10.1002\/jbmr.4143","volume":"35","author":"D Dumuid","year":"2020","unstructured":"Dumuid, D. et al. The \u201cGoldilocks day\u201d for children\u2019s skeletal health: compositional data analysis of 24-hour activity behaviors. J. Bone Miner. Res. 35, 2393\u20132403 (2020).","journal-title":"J. Bone Miner. Res."},{"key":"2542_CR8","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjpad.2025.100333","volume":"12","author":"MH Huque","year":"2025","unstructured":"Huque, M. H. et al. A critical review and classification of dementia risk assessment tools to inform dementia risk reduction. J. Prev. Alzheimer\u2019s. Dis. 12, 100333 (2025).","journal-title":"J. Prev. Alzheimer\u2019s. Dis."},{"key":"2542_CR9","doi-asserted-by":"crossref","unstructured":"Mellow, M. L. et al. \u2018Small Steps\u2019 towards improving 24-hour time-use behaviours to decrease the risk of dementia: protocol for a personalised, web-based randomised controlled trial in community-dwelling older adults. BMJ Open. 15, e105643 (2025).","DOI":"10.1136\/bmjopen-2025-105643"},{"key":"2542_CR10","doi-asserted-by":"publisher","first-page":"e1001779","DOI":"10.1371\/journal.pmed.1001779","volume":"12","author":"C Sudlow","year":"2015","unstructured":"Sudlow, C. et al. UK Biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age. PLOS Med. 12, e1001779 (2015).","journal-title":"PLOS Med."},{"key":"2542_CR11","unstructured":"Chang, W. et al. shiny: Web Application Framework for R. R package version 1.13.0.9000, https:\/\/shiny.posit.co\/."},{"key":"2542_CR12","doi-asserted-by":"publisher","unstructured":"Blake, H. T. et al. Co-design of a digital 24-hour time-use intervention with older adults and allied health professionals. Front. Digit. Health. https:\/\/doi.org\/10.3389\/fdgth.2025.1544489 (2025).","DOI":"10.3389\/fdgth.2025.1544489"},{"key":"2542_CR13","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-024-05186-z","volume":"24","author":"S Zahran","year":"2024","unstructured":"Zahran, S. et al. Optimal levels of sleep, sedentary behaviour, and physical activity needed to support cognitive function in children of the early years. BMC Pediatr. 24, 735 (2024).","journal-title":"BMC Pediatr."},{"key":"2542_CR14","unstructured":"Tolosana-Delgado, R., Arya, E., Khodadadzadeh, M. & Boogaart, K. On Machine Learning Algorithms and Compositional Data (2019)."},{"key":"2542_CR15","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afaf072","volume":"54","author":"AM Collins","year":"2025","unstructured":"Collins, A. M. et al. 24-Hour time use and cognitive performance in late adulthood: results from the Investigating Gains in Neurocognition in an Intervention Trial of Exercise (IGNITE) study. Age Ageing 54, afaf072 (2025).","journal-title":"Age Ageing"},{"key":"2542_CR16","volume":"79","author":"ML Mellow","year":"2024","unstructured":"Mellow, M. L. et al. Should we work smarter or harder for our health? A comparison of intensity and domain-based time-use compositions and their associations with cognitive and cardiometabolic health. J. Gerontology: Ser. A 79, glae233 (2024).","journal-title":"J. Gerontology: Ser. A"},{"key":"2542_CR17","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.3233\/JAD-220181","volume":"88","author":"D Dumuid","year":"2022","unstructured":"Dumuid, D. et al. Does APOE \u025b4 status change how 24-hour time-use composition is associated with cognitive function? An exploratory analysis among middle-to-older adults. J. Alzheimer\u2019s. Dis. 88, 1157\u20131165 (2022).","journal-title":"J. Alzheimer\u2019s. Dis."},{"key":"2542_CR18","doi-asserted-by":"publisher","DOI":"10.1186\/s12966-023-01557-4","volume":"21","author":"ML Mellow","year":"2024","unstructured":"Mellow, M. L. et al. Cross-sectional associations between 24-hour time-use composition, grey matter volume and cognitive function in healthy older adults. Int. J. Behav. Nutr. Phys. Act. 21, 11 (2024).","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"2542_CR19","doi-asserted-by":"publisher","unstructured":"Mellow, M. L. et al. Twenty-four-hour time-use composition and cognitive function in older adults: cross-sectional findings of the ACTIVate study. Front. Hum. Neurosci. https:\/\/doi.org\/10.3389\/fnhum.2022.1051793 (2022).","DOI":"10.3389\/fnhum.2022.1051793"},{"key":"2542_CR20","doi-asserted-by":"publisher","unstructured":"Wu, Y. et al. Analysis of the 24-h activity cycle: an illustration examining the association with cognitive function in the Adult Changes in Thought study. Front. Psychol. https:\/\/doi.org\/10.3389\/fpsyg.2023.1083344 (2023).","DOI":"10.3389\/fpsyg.2023.1083344"},{"key":"2542_CR21","volume":"79","author":"GM Balbim","year":"2024","unstructured":"Balbim, G. M. et al. The association of the 24-hour activity cycle profiles with cognition in older adults with mild cognitive impairment: a cross-sectional study. J. Gerontology: Ser. A 79, glae099 (2024).","journal-title":"J. Gerontology: Ser. A"},{"key":"2542_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2022.111698","volume":"159","author":"ML Mellow","year":"2022","unstructured":"Mellow, M. L. et al. How are combinations of physical activity, sedentary behaviour and sleep related to cognitive function in older adults? A systematic review. Exp. Gerontol. 159, 111698 (2022).","journal-title":"Exp. Gerontol."},{"key":"2542_CR23","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1146\/annurev-clinpsy-072720-014213","volume":"18","author":"KI Erickson","year":"2022","unstructured":"Erickson, K. I., Donofry, S. D., Sewell, K. R., Brown, B. M. & Stillman, C. M. Cognitive Aging and the Promise of Physical Activity. Annu. Rev. Clin. Psychol. 18, 417\u2013442 (2022).","journal-title":"Annu. Rev. Clin. Psychol."},{"key":"2542_CR24","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1136\/bjsports-2024-108589","volume":"59","author":"B Singh","year":"2025","unstructured":"Singh, B. et al. Effectiveness of exercise for improving cognition, memory and executive function: a systematic umbrella review and meta-meta-analysis. Brit. J. Sports Med 59, 866\u2013876 (2025).","journal-title":"Brit. J. Sports Med"},{"key":"2542_CR25","doi-asserted-by":"publisher","first-page":"2339","DOI":"10.1007\/s40520-019-01460-8","volume":"32","author":"L Coelho","year":"2020","unstructured":"Coelho, L. et al. The association between sedentary behavior and cognitive ability in older adults. Aging Clin. Exp. Res. 32, 2339\u20132347 (2020).","journal-title":"Aging Clin. Exp. Res."},{"key":"2542_CR26","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1007\/s40279-019-01186-7","volume":"50","author":"CM Maasakkers","year":"2020","unstructured":"Maasakkers, C. M. et al. The association of sedentary behaviour and cognitive function in people without dementia: a coordinated analysis across five cohort studies from COSMIC. Sports Med. 50, 403\u2013413 (2020).","journal-title":"Sports Med."},{"key":"2542_CR27","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1007\/s40520-019-01457-3","volume":"32","author":"O Olanrewaju","year":"2020","unstructured":"Olanrewaju, O., Stockwell, S., Stubbs, B. & Smith, L. Sedentary behaviours, cognitive function, and possible mechanisms in older adults: a systematic review. Aging Clin. Exp. Res. 32, 969\u2013984 (2020).","journal-title":"Aging Clin. Exp. Res."},{"key":"2542_CR28","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.sleep.2015.08.021","volume":"17","author":"JC Lo","year":"2016","unstructured":"Lo, J. C., Groeger, J. A., Cheng, G. H., Dijk, D.-J. & Chee, M. W. L. Self-reported sleep duration and cognitive performance in older adults: a systematic review and meta-analysis. Sleep. Med. 17, 87\u201398 (2016).","journal-title":"Sleep. Med."},{"key":"2542_CR29","doi-asserted-by":"publisher","first-page":"613","DOI":"10.5664\/jcsm.3782","volume":"10","author":"TE Gildner","year":"2014","unstructured":"Gildner, T. E., Liebert, M. A., Kowal, P., Chatterji, S. & Snodgrass, J. J. Associations between sleep duration, sleep quality, and cognitive test performance among older adults from six middle income countries: results from the Study on Global Ageing and Adult Health (SAGE). J. Clin. sleep. Med. 10, 613\u2013621 (2014).","journal-title":"J. Clin. sleep. Med."},{"key":"2542_CR30","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1159\/000442418","volume":"46","author":"EE Devore","year":"2016","unstructured":"Devore, E. E., Grodstein, F. & Schernhammer, E. S. Sleep duration in relation to cognitive function among older adults: a systematic review of observational studies. Neuroepidemiology 46, 57\u201378 (2016).","journal-title":"Neuroepidemiology"},{"key":"2542_CR31","doi-asserted-by":"publisher","first-page":"S57","DOI":"10.1139\/apnm-2020-0467","volume":"45","author":"R Ross","year":"2020","unstructured":"Ross, R. et al. Canadian 24-hour movement guidelines for adults aged 18\u201364 years and adults aged 65 years or older: an integration of physical activity, sedentary behaviour, and sleep. Appl. Physiol. Nutr. Metab. 45, S57\u2013S102 (2020).","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"2542_CR32","doi-asserted-by":"publisher","DOI":"10.1186\/s12966-023-01526-x","volume":"20","author":"A Miatke","year":"2023","unstructured":"Miatke, A. et al. The association between reallocations of time and health using compositional data analysis: a systematic scoping review with an interactive data exploration interface. Int. J. Behav. Nutr. Phys. Act. 20, 127 (2023).","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"2542_CR33","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1007\/s12603-023-2046-2","volume":"27","author":"CB Castro","year":"2023","unstructured":"Castro, C. B. et al. Multi-domain interventions for dementia prevention\u2014a systematic review. J. Nutr. Health Aging 27, 1271\u20131280 (2023).","journal-title":"J. Nutr. Health Aging"},{"key":"2542_CR34","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1016\/S0140-6736(20)30367-6","volume":"396","author":"G Livingston","year":"2020","unstructured":"Livingston, G. et al. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet 396, 413\u2013446 (2020).","journal-title":"Lancet"},{"key":"2542_CR35","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1136\/bjsports-2021-104050","volume":"56","author":"R Walmsley","year":"2022","unstructured":"Walmsley, R. et al. Reallocation of time between device-measured movement behaviours and risk of incident cardiovascular disease. Br. J. Sports Med. 56, 1008 (2022).","journal-title":"Br. J. Sports Med."},{"key":"2542_CR36","doi-asserted-by":"publisher","first-page":"3726","DOI":"10.1177\/0962280217710835","volume":"27","author":"D Dumuid","year":"2017","unstructured":"Dumuid, D. et al. Compositional data analysis for physical activity, sedentary time and sleep research. Stat. Methods Med. Res. 27, 3726\u20133738 (2017).","journal-title":"Stat. Methods Med. Res."},{"key":"2542_CR37","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.chemolab.2015.02.019","volume":"143","author":"J Palarea-Albaladejo","year":"2015","unstructured":"Palarea-Albaladejo, J. & Mart\u00edn-Fern\u00e1ndez, J. A. zCompositions \u2014 R package for multivariate imputation of left-censored data under a compositional approach. Chemometr. Intell. Lab. Syst. 143, 85\u201396 (2015).","journal-title":"Chemometr. Intell. Lab. Syst."},{"key":"2542_CR38","doi-asserted-by":"publisher","first-page":"2688","DOI":"10.1016\/j.csda.2012.02.012","volume":"56","author":"JA Mart\u00edn-Fern\u00e1ndez","year":"2012","unstructured":"Mart\u00edn-Fern\u00e1ndez, J. A., Hron, K., Templ, M., Filzmoser, P. & Palarea-Albaladejo, J. Model-based replacement of rounded zeros in compositional data: Classical and robust approaches. Comput. Stat. Data Anal. 56, 2688\u20132704 (2012).","journal-title":"Comput. Stat. Data Anal."},{"key":"2542_CR39","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1146\/annurev.psych.59.103006.093656","volume":"60","author":"DC Park","year":"2009","unstructured":"Park, D. C. & Reuter-Lorenz, P. The adaptive brain: aging and neurocognitive scaffolding. Annu. Rev. Psychol. 60, 173\u2013196 (2009).","journal-title":"Annu. Rev. Psychol."},{"key":"2542_CR40","doi-asserted-by":"publisher","first-page":"227","DOI":"10.31887\/DCNS.2019.21.3\/pharvey","volume":"21","author":"PD Harvey","year":"2019","unstructured":"Harvey, P. D. Domains of cognition and their assessment. Dialogues Clin. Neurosci. 21, 227\u2013237 (2019).","journal-title":"Dialogues Clin. Neurosci."},{"key":"2542_CR41","doi-asserted-by":"publisher","first-page":"1592","DOI":"10.1093\/ije\/dyad009","volume":"52","author":"T Campbell","year":"2023","unstructured":"Campbell, T. & Cullen, B. Estimating the effect of physical activity on cognitive function within the UK Biobank cohort. Int. J. Epidemiol. 52, 1592\u20131611 (2023).","journal-title":"Int. J. Epidemiol."},{"key":"2542_CR42","unstructured":"R: A language and environment for statistical computing (R Foundation for Statistical Computing, 2023)."},{"key":"2542_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.18637\/jss.v033.i01","volume":"33","author":"JH Friedman","year":"2010","unstructured":"Friedman, J. H., Hastie, T. & Tibshirani, R. Regularization paths for generalized linear models via coordinate descent. J. Stat. Softw. 33, 1\u201322 (2010).","journal-title":"J. Stat. Softw."},{"key":"2542_CR44","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1111\/j.1467-9868.2005.00532.x","volume":"68","author":"M Yuan","year":"2006","unstructured":"Yuan, M. & Lin, Y. Model selection and estimation in regression with grouped variables. J. R. Stat. Soc. Ser. B: Stat. Methodol. 68, 49\u201367 (2006).","journal-title":"J. R. Stat. Soc. Ser. B: Stat. Methodol."},{"key":"2542_CR45","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/s11222-013-9424-2","volume":"25","author":"P Breheny","year":"2015","unstructured":"Breheny, P. & Huang, J. Group descent algorithms for nonconvex penalized linear and logistic regression models with grouped predictors. Stat. Comput. 25, 173\u2013187 (2015).","journal-title":"Stat. Comput."},{"key":"2542_CR46","doi-asserted-by":"crossref","unstructured":"Hastie, T., Tibshirani, R. & Friedman, J. H. The Elements of Statistical Learning: Data Mining, Inference, and Prediction 2nd edn (Springer, 2009).","DOI":"10.1007\/978-0-387-84858-7"},{"key":"2542_CR47","first-page":"231","volume":"39","author":"J-A Mart\u00edn-Fern\u00e1ndez","year":"2015","unstructured":"Mart\u00edn-Fern\u00e1ndez, J.-A., Daunis i Estadella, J. & Mateu-Figueras, G. On the interpretation of differences between groups for compositional data. SORT: Stat. Oper. Res. Trans. 39, 231\u2013252 (2015).","journal-title":"SORT: Stat. Oper. Res. Trans."}],"container-title":["npj Digital Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41746-026-02542-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41746-026-02542-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41746-026-02542-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:16:44Z","timestamp":1777936604000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41746-026-02542-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,17]]},"references-count":47,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["2542"],"URL":"https:\/\/doi.org\/10.1038\/s41746-026-02542-4","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-6897341\/v1","asserted-by":"object"}]},"ISSN":["2398-6352"],"issn-type":[{"value":"2398-6352","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,17]]},"assertion":[{"value":"15 June 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"354"}}