{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T09:52:17Z","timestamp":1770976337410,"version":"3.50.1"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2002,9,27]],"date-time":"2002-09-27T00:00:00Z","timestamp":1033084800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Obes"],"published-print":{"date-parts":[[2002,10]]},"DOI":"10.1038\/sj.ijo.0802137","type":"journal-article","created":{"date-parts":[[2002,10,15]],"date-time":"2002-10-15T10:59:52Z","timestamp":1034679592000},"page":"1310-1316","source":"Crossref","is-referenced-by-count":136,"title":["Association of physical activity with insulin sensitivity in children"],"prefix":"10.1038","volume":"26","author":[{"given":"KH","family":"Schmitz","sequence":"first","affiliation":[]},{"suffix":"Jr","given":"DR","family":"Jacobs","sequence":"additional","affiliation":[]},{"given":"C-P","family":"Hong","sequence":"additional","affiliation":[]},{"given":"J","family":"Steinberger","sequence":"additional","affiliation":[]},{"given":"A","family":"Moran","sequence":"additional","affiliation":[]},{"given":"AR","family":"Sinaiko","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2002,9,27]]},"reference":[{"key":"BF0802137_CR1","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/S0002-9343(97)00027-2","volume":"103","author":"SM Haffner","year":"1997","unstructured":"Haffner SM, Miettinen H . Insulin resistance implications for type II diabetes mellitus and coronary heart disease Am J Med 1997 103: 152\u2013162.","journal-title":"Am J Med"},{"key":"BF0802137_CR2","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1056\/NEJM199107183250302","volume":"325","author":"SP Helmrich","year":"1991","unstructured":"Helmrich SP, Ragland DR, Leung RW, Paffenbarger RS Jr . Physical activity and reduced occurrence of non-insulin-dependent diabetes mellitus New Engl J Med 1991 325: 147\u2013152.","journal-title":"New Engl J Med"},{"key":"BF0802137_CR3","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1016\/0140-6736(91)90664-B","volume":"338","author":"JE Manson","year":"1991","unstructured":"Manson JE, Rimm EB, Stampfer MJ, Colditz GA, Willett WC, Krolewski AS, Rosner B, Hennekens CH, Speizer FE . Physical activity and incidence of non-insulin-dependent diabetes mellitus in women Lancet 1991 338: 774\u2013778.","journal-title":"Lancet"},{"key":"BF0802137_CR4","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1007\/BF00400196","volume":"34","author":"K-F Eriksson","year":"1991","unstructured":"Eriksson K-F, Lindgarde F . Prevention of type 2 (non-insulin-dependent) diabetes mellitus by diet and physical exercise Diabetologica 1991 34: 891\u2013898.","journal-title":"Diabetologica"},{"key":"BF0802137_CR5","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.0954-6820.1986.tb08932.x","volume":"711","author":"JO Holloszy","year":"1986","unstructured":"Holloszy JO, Schultz J, Kusnierkiewicz J, Hagberg JM, Ehsani AA . Effects of exercise on glucose tolerance and insulin resistance: brief review and some preliminary results Acta Med Scand Suppl 1986 711: 55\u201365.","journal-title":"Acta Med Scand Suppl"},{"key":"BF0802137_CR6","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1001\/jama.279.9.669","volume":"279","author":"EJ Mayer-Davis","year":"1998","unstructured":"Mayer-Davis EJ, D'Agostino R Jr, Karter AJ, Haffner SM, Rewers MJ, Saad M, Bergman RN . Intensity and amount of physical activity in relation to insulin sensitivity: The insulin resistance atherosclerosis study JAMA 1998 279: 669\u2013674.","journal-title":"JAMA"},{"key":"BF0802137_CR7","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1123\/pes.6.4.361","volume":"6","author":"BS Alpert","year":"1994","unstructured":"Alpert BS, Wilmore JH . Physical activity and blood pressure in adolescents Pediat Exerc Sci 1994 6: 361\u2013380.","journal-title":"Pediat Exerc Sci"},{"key":"BF0802137_CR8","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1123\/pes.6.4.381","volume":"6","author":"N Armstrong","year":"1994","unstructured":"Armstrong N, Simons-Morton B . Physical activity and blood lipids in adolescents Pediat Exerc Sci 1994 6: 381\u2013405.","journal-title":"Pediat Exerc Sci"},{"key":"BF0802137_CR9","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1038\/sj.ijo.0800968","volume":"22","author":"MA Ferguson","year":"1999","unstructured":"Ferguson MA, Gutin B, Le N, Karp W, Litaker M, Humphries M, Okuyama T, Riggs S, Owens S . Effects of exercise training and its cessation on components of the insulin resistance syndrome in obese children Int J Obes Relat Metab Disord 1999 22: 889\u2013895.","journal-title":"Int J Obes Relat Metab Disord"},{"issue":"6 Suppl","key":"BF0802137_CR10","doi-asserted-by":"publisher","first-page":"S484","DOI":"10.1097\/00005768-200106001-00018","volume":"33","author":"R Fagard","year":"2001","unstructured":"Fagard R . Exercise characteristics and the blood pressure response to dynamic physical training Med Sci Sports Exerc 2001 33 (6 Suppl): S484\u2013S492.","journal-title":"Med Sci Sports Exerc"},{"issue":"6 Suppl","key":"BF0802137_CR11","doi-asserted-by":"publisher","first-page":"S495","DOI":"10.1097\/00005768-200106001-00020","volume":"33","author":"DE Kelley","year":"2001","unstructured":"Kelley DE, Goodpaster BH . Effects of exercise on glucose homeostasis in Type 2 diabetes mellitus Med Sci Sports Exerc 2001 33 (6 Suppl): S495\u2013S501.","journal-title":"Med Sci Sports Exerc"},{"issue":"6 Suppl","key":"BF0802137_CR12","doi-asserted-by":"publisher","first-page":"S502","DOI":"10.1097\/00005768-200106001-00021","volume":"33","author":"AS Leon","year":"2001","unstructured":"Leon AS, Sanchez OA . Response of blood lipids to exercise training alone or combined with dietary intervention Med Sci Sports Exerc 2001 33 (6 Suppl): S502\u2013S515.","journal-title":"Med Sci Sports Exerc"},{"key":"BF0802137_CR13","doi-asserted-by":"publisher","first-page":"819","DOI":"10.3177\/jnsv.44.819","volume":"44","author":"I Matsui","year":"1998","unstructured":"Matsui I, Nambu S, Baba S . Evaluation of fasting serum insulin levels among Japanese school-age children J Nutr Sci Vitaminol 1998 44: 819\u2013828.","journal-title":"J Nutr Sci Vitaminol"},{"key":"BF0802137_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1055\/s-2007-972799","volume":"17","author":"EB Kahle","year":"1996","unstructured":"Kahle EB, Zipf WB, Lamb DR, Horswill CA, Ward KM . Association between mild, routine exercise and improved insulin dynamics and glucose control in obese adolescents Int J Sports Med 1996 17: 1\u20136.","journal-title":"Int J Sports Med"},{"key":"BF0802137_CR15","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1291\/hypres.23.227","volume":"23","author":"H Kawabe","year":"2000","unstructured":"Kawabe H, Murata K, Shibata H, Hirose H, Tsujioka M, Saito I, Saruta T . Participation in school sports clubs and related effects on cardiovascular risk factors in young males Hypertens Res 2000 23: 227\u2013232.","journal-title":"Hypertens Res"},{"key":"BF0802137_CR16","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1093\/oxfordjournals.aje.a117239","volume":"140","author":"OT Raitakari","year":"1994","unstructured":"Raitakari OT, Porkka KVK, Taimela S, Telama R, Rasanen L, Viikari JSA . Effects of persistent physical activity and inactivity on coronary risk factors in children and young adults Am J Epidemiol 1994 140: 195\u2013205.","journal-title":"Am J Epidemiol"},{"key":"BF0802137_CR17","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1161\/01.HYP.10.3.267","volume":"10","author":"AP Rocchini","year":"1987","unstructured":"Rocchini AP, Katch V, Schork A, Kelch RP . Insulin and blood pressure during weight loss in obese adolescents Hypertension 1987 10: 267\u2013273.","journal-title":"Hypertension"},{"key":"BF0802137_CR18","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1016\/S0022-3476(96)80124-7","volume":"128","author":"OL Pinhas-Hamiel","year":"1996","unstructured":"Pinhas-Hamiel OL, Dolan M, Daniels SR, Standiford D, Khoury PR, Zeitler P . Increased incidence of non-insulin dependent mellitus among adolescents J Pediatr 1996 128: 608\u2013615.","journal-title":"J Pediatr"},{"key":"BF0802137_CR19","first-page":"32","volume-title":"Growth at Adolescence","author":"JM Tanner","year":"1962","unstructured":"Tanner JM . Growth at Adolescence 2nd edn Blackwell: Oxford 1962 32\u201333."},{"key":"BF0802137_CR20","first-page":"681","volume":"56","author":"MH Slaughter","year":"1984","unstructured":"Slaughter MH, Lohman TG, Boileau RA, Stillman RJ, Van Loan M, Horswill CA, Wilmore JH . Influence of maturation on relationship of skinfolds to body density: a cross-sectional study Hum Biol 1984 56: 681\u2013689.","journal-title":"Hum Biol"},{"key":"BF0802137_CR21","first-page":"709","volume":"60","author":"MH Slaughter","year":"1988","unstructured":"Slaughter MH, Lohman TG, Boileau RA, Horswill CA, Stillman RJ, Van Loan MD, Bemben DA . Skinfold equations for estimation of body fatness in children and youth Hum Biol 1988 60: 709\u2013723.","journal-title":"Hum Biol"},{"key":"BF0802137_CR22","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1093\/oxfordjournals.aje.a112608","volume":"108","author":"RS Paffenbarger","year":"1978","unstructured":"Paffenbarger RS, Wing AL, Hyde RT . Physical activity as an index of heart attack risk in college alumni Am J Epidemiol 1978 108: 161\u2013175.","journal-title":"Am J Epidemiol"},{"key":"BF0802137_CR23","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1097\/00005768-199705001-01074","volume":"29","author":"MA Pereira","year":"1997","unstructured":"Pereira MA, FitzGerald SJ, Gregg EW, Joswiak ML, Ryan WJ, Suminski RR, Utter AC, Zmuda JM . A collection of physical activity questionnaires for health-related research Med Sci Sports Exerc 1997 29: S1\u2013S201.","journal-title":"Med Sci Sports Exerc"},{"key":"BF0802137_CR24","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1249\/00005768-199301000-00014","volume":"25","author":"JF Sallis","year":"1993","unstructured":"Sallis JF, Buono MJ, Roby JJ, Micale FG, Nelson JA . Seven-day recall and other physical activity self-reports in children and adolescents Med Sci Sports Exerc 1993 25: 99\u2013108.","journal-title":"Med Sci Sports Exerc"},{"key":"BF0802137_CR25","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","volume":"18","author":"WT Friedewald","year":"1972","unstructured":"Friedewald WT, Levy RI, Fredrickson DS . Estimation of the concentration of low-density lipoprotein cholesterol in plasma without the use of the preparative ultracentrifuge Clin Chem 1972 18: 499\u2013502.","journal-title":"Clin Chem"},{"key":"BF0802137_CR26","first-page":"633","volume-title":"Physical activity, fitness, and health","author":"RH Fagard","year":"1994","unstructured":"Fagard RH, Tipton CM . Physical activity, fitness, and hypertension. In: Bouchard C, Shephard RJ, Stephens T (eds) Physical activity, fitness, and health Human Kinetics: Champaign, IL 1994 pp 633\u2013655."},{"key":"BF0802137_CR27","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1146\/annurev.med.49.1.235","volume":"49","author":"LJ Goodyear","year":"1998","unstructured":"Goodyear LJ, Kahn BB . Exercise, glucose transport, and insulin sensitivity A Rev Med 1998 49: 235\u2013261.","journal-title":"A Rev Med"},{"key":"BF0802137_CR28","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1056\/NEJM199610313351804","volume":"335","author":"G Perseghin","year":"1996","unstructured":"Perseghin G, Price TB, Petersen KF, Roden M, Cline GW, Gerow K, Rothman DL, Shulman GL . Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects New Engl J Med 1996 335: 1357\u20131362.","journal-title":"New Engl J Med"},{"key":"BF0802137_CR29","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1056\/NEJM199001253220403","volume":"322","author":"GI Shulman","year":"1990","unstructured":"Shulman GI, Landenson PW, Wolfe MH, Ridgway EC, Wolfe RR . Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy New Engl J Med 1990 322: 223\u2013228.","journal-title":"New Engl J Med"},{"key":"BF0802137_CR30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/00004872-200203000-00027","volume":"20","author":"AR Sinaiko","year":"2002","unstructured":"Sinaiko AR, Steinberger J, Moran A, Prineas RJ, Jacobs DR Jr . Relation of insulin resistance to blood pressure in childhood J Hypertension 2002 20: 1\u20139.","journal-title":"J Hypertension"},{"key":"BF0802137_CR31","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1001\/jama.279.12.938","volume":"279","author":"RE Andersen","year":"1998","unstructured":"Andersen RE, Crespo CJ, Bartlett SJ, Cheskin LJ, Pratt M . Relationship of physical activity and television watching with body weight and level of fatness among children: results from the Third National Health and Nutrition Examination Survey JAMA 1998 279: 938\u2013942.","journal-title":"JAMA"},{"issue":"4, part 1 of 2","key":"BF0802137_CR32","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1542\/peds.105.4.e56","volume":"105","author":"CS Berkey","year":"2000","unstructured":"Berkey CS, Rockett HR, Field EA, Gillman MW, Frazier AL, Camargo CA Jr, Colditz GA . Activity, dietary intake, and weight changes in a longitudinal study of preadolescent and adolescent boys and girls Pediatrics 2000 105 (4, part 1 of 2): 854.","journal-title":"Pediatrics"},{"key":"BF0802137_CR33","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1038\/sj.ijo.0800605","volume":"22","author":"MS Treuth","year":"1998","unstructured":"Treuth MS, Figueroa-Colon R, Hunter GR, Weinsier RL, Butte NF, Goran MI . Energy expenditure and physical fitness in overweight vs non-overweight prepubertal girls Int J Obes Relat Metab Disord 1998 22: 440\u2013447.","journal-title":"Int J Obes Relat Metab Disord"},{"key":"BF0802137_CR34","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1002\/j.1550-8528.1997.tb00578.x","volume":"5","author":"DS Ward","year":"1997","unstructured":"Ward DS, Trost SG, Felton G, Saunders R, Parsons MA, Dowda M, Pate RR . Physical activity and physical fitness in African-American girls with and without obesity Obes Res 1997 5: 572\u2013577.","journal-title":"Obes Res"},{"key":"BF0802137_CR35","doi-asserted-by":"publisher","first-page":"99","DOI":"10.2165\/00007256-200029020-00003","volume":"29","author":"K Tolfrey","year":"2000","unstructured":"Tolfrey K, Jones AM, Campbell IG . The effect of aerobic exercise training on the lipid-lipoprotein profile of children and adolescents Sports Med 2000 29: 99\u2013112.","journal-title":"Sports Med"},{"key":"BF0802137_CR36","unstructured":"Centers for Disease Control and Prevention (CDC). Youth risk behavior surveillance\u2014United States, 1999 CDC Surveillance Summaries MMWR 2000 p 49 (no. SS-5)"},{"key":"BF0802137_CR37","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/S0749-3797(18)30182-X","volume":"13","author":"R Telama","year":"1997","unstructured":"Telama R, Yang X, Laakso L, Viikari J . Physical activity in childhood and adolescence as predictor of physical activity in young adulthood Am J Prev Med 1997 13: 317\u2013323.","journal-title":"Am J Prev Med"}],"container-title":["International Journal of Obesity"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/0802137.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/0802137","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/0802137.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,7]],"date-time":"2024-01-07T07:27:22Z","timestamp":1704612442000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/0802137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,9,27]]},"references-count":37,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2002,10]]}},"alternative-id":["BF0802137"],"URL":"https:\/\/doi.org\/10.1038\/sj.ijo.0802137","relation":{},"ISSN":["0307-0565","1476-5497"],"issn-type":[{"value":"0307-0565","type":"print"},{"value":"1476-5497","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,9,27]]}}}